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UBR2 Antibody (PCRP-UBR2-1D12) [Janelia Fluor® 646]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, Flow, ICC/IF, IHC, IP, MA
Clone
PCRP-UBR2-1D12
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 646

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP3-14287AF350
Alexa Fluor 405
NBP3-14287AF405
Alexa Fluor 488
NBP3-14287AF488
Alexa Fluor 532
NBP3-14287AF532
Alexa Fluor 594
NBP3-14287AF594
Alexa Fluor 647
NBP3-14287AF647
Alexa Fluor 700
NBP3-14287AF700
Alexa Fluor 750
NBP3-14287AF750
Allophycocyanin
NBP3-14287APC
Biotin
NBP3-14287B
DyLight 350
NBP3-14287UV
DyLight 405
NBP3-14287V
DyLight 488
NBP3-14287G
DyLight 550
NBP3-14287R
DyLight 594
NBP3-14287DL594
DyLight 650
NBP3-14287C
DyLight 680
NBP3-14287FR
DyLight 755
NBP3-14287IR
FITC
NBP3-14287F
HRP
NBP3-14287H
Janelia Fluor 549
NBP3-14287JF549
PE
NBP3-14287PE
PerCP
NBP3-14287PCP
Unconjugated
NBP3-13900-100ug
mFluor Violet 450 SE
NBP3-14287MFV450
mFluor Violet 500 SE
NBP3-14287MFV500
mFluor Violet 610 SE
NBP3-14287MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP3-13900-100ug
Azide and BSA Free
NBP3-14287
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UBR2 Antibody (PCRP-UBR2-1D12) [Janelia Fluor® 646] Summary

Immunogen
Recombinant full-length human UBR2 protein (Uniprot: Q8IWV8)
Localization
Nucleus
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
UBR2
Purity
Protein A or G purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry-Paraffin
  • Immunoprecipitation
  • Protein Array
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

0

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for UBR2 Antibody (PCRP-UBR2-1D12) [Janelia Fluor® 646]

  • bA49A4.1
  • C6orf133MGC71112
  • chromosome 6 open reading frame 133
  • dJ242G1.1
  • dJ392M17.3
  • DKFZp686C08114
  • E3 ubiquitin-protein ligase UBR2
  • EC 6.3.2.-
  • KIAA0349FLJ36357
  • N-recognin-2
  • RP3-392M17.3
  • ubiquitin protein ligase E3 component n-recognin 2
  • Ubiquitin-protein ligase E3-alpha-2
  • Ubiquitin-protein ligase E3-alpha-II

Background

Proteolysis by the ubiquitin-proteasome system controls the concentration of many regulatory proteins. The selectivity of ubiquitylation is determined by ubiquitin E3 ligases, which recognize the substrate's destabilization signal, or degron. The E3 ligase UBR2 participates in the N-end rule pathway, which targets proteins bearing an N-terminal degron, or N-degron (Kwon et al., 2003 [PubMed 14585983]).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol UBR2