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TrkC Antibody (OTI2B8) - Azide and BSA Free

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Western Blot: TrkC Antibody (OTI2B8) - Azide and BSA Free [NBP2-74626] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TrkC (Right lane) cDNA for 48 hrs and lysed. Equivalent ...read more
Immunocytochemistry/ Immunofluorescence: TrkC Antibody (OTI2B8) - Azide and BSA Free [NBP2-74626] - Staining of COS7 cells transiently transfected by pCMV6-ENTRY TrkC.
Immunohistochemistry: TrkC Antibody (OTI2B8) - Azide and BSA Free [NBP2-74626] - Staining of paraffin-embedded Carcinoma of Human pancreas tissue using anti-TrkC mouse monoclonal antibody.
Western Blot: TrkC Antibody (OTI2B8) - Azide and BSA Free [NBP2-74626] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TrkC (Right lane) cDNA for 48 hrs and lysed. Equivalent ...read more
Immunohistochemistry: TrkC Antibody (OTI2B8) - Azide and BSA Free [NBP2-74626] - Staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-TrkC mouse monoclonal antibody.
Immunohistochemistry: TrkC Antibody (OTI2B8) - Azide and BSA Free [NBP2-74626] - Staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-TrkC mouse monoclonal antibody.
Immunohistochemistry: TrkC Antibody (OTI2B8) - Azide and BSA Free [NBP2-74626] - Staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-TrkC mouse monoclonal antibody.
Immunohistochemistry: TrkC Antibody (OTI2B8) - Azide and BSA Free [NBP2-74626] - Staining of paraffin-embedded Carcinoma of Human bladder tissue using anti-TrkC mouse monoclonal antibody.
Immunohistochemistry: TrkC Antibody (OTI2B8) - Azide and BSA Free [NBP2-74626] - Staining of paraffin-embedded Carcinoma of Human kidney tissue using anti-TrkC mouse monoclonal antibody.
Immunohistochemistry: TrkC Antibody (OTI2B8) - Azide and BSA Free [NBP2-74626] - Staining of paraffin-embedded Carcinoma of Human liver tissue using anti-TrkC mouse monoclonal antibody.
Immunohistochemistry: TrkC Antibody (OTI2B8) - Azide and BSA Free [NBP2-74626] - Staining of paraffin-embedded Carcinoma of Human lung tissue using anti-TrkC mouse monoclonal antibody.
Immunohistochemistry: TrkC Antibody (OTI2B8) - Azide and BSA Free [NBP2-74626] - Staining of paraffin-embedded Carcinoma of Human thyroid tissue using anti-TrkC mouse monoclonal antibody.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ICC/IF, IHC
Clone
OTI2B8
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Format
Azide and BSA Free
Concentration
LYOPH

Order Details

TrkC Antibody (OTI2B8) - Azide and BSA Free Summary

Immunogen
Full-length protein expressed in 293T cell transfected with human NTRK3 expression vector
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
NTRK3
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 1:100
  • Immunohistochemistry 1:50
  • Western Blot 1:2000
Theoretical MW
94.4 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
Lyophilized from PBS (pH 7.3) with 8% Trehalose
Preservative
No Preservative
Concentration
LYOPH
Purity
Immunogen affinity purified
Reconstitution Instructions
Reconstitute with PBS (pH 7.3). To use this carrier-free antibody for conjugation experiments, another round of desalting is highly recommended.

Alternate Names for TrkC Antibody (OTI2B8) - Azide and BSA Free

  • EC 2.7.10
  • EC 2.7.10.1
  • ETS related protein-neurotrophic receptor tyrosine kinase fusion protein
  • ETV6-NTRK3 fusion
  • gp145(trkC)
  • GP145-TrkC
  • Neurotrophic tyrosine kinase receptor type 3
  • neurotrophic tyrosine kinase, receptor, type 3
  • NT 3 receptor
  • NT-3 growth factor receptor
  • NTRK3
  • TrkC tyrosine kinase
  • TrkC
  • trk-C
  • TRKCneurotrophin 3 receptor
  • tyrosine kinase receptor C

Background

TrkC (tyrosine kinase receptor C) is a receptor for neurotrophin-3. TrkC is a member of receptor tyrosine kinases and may have a role in proprioceptive neuron development. TrkC has been studied in relation to various diseases and disorders including leukemia, breast cancer, fibrosarcoma, Alzheimer's disease, Parkinson's disease and several others.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for TrkC Antibody (NBP2-74626) (0)

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Secondary Antibodies

 

Isotype Controls

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Research Areas for TrkC Antibody (NBP2-74626)

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Blogs on TrkC.

Successful Transplantation of Friedreich Ataxia Induced Pluripotent Stem Cell (iPSC)-Derived Sensory Neurons in Dorsal Root Ganglia of Adult Rodents
Jamshed Arslan, Pharm D, PhD The dorsal root ganglia (DRG) are a collection of cell bodies of sensory nerves carrying sensory information – including nociception, mechanoreception and proprioception – from periphera...  Read full blog post.

TrkB: Bridging Ontogenesis and Oncogenesis
Tropomyosin receptor kinase B (TrkB) is a member of the Trk receptor tyrosine kinases family consisting of TrkA, TrkB and TrkC. The sequence of these family members is highly conserved. Interaction of brain-derived neurotrophic factor (BDNF) with its ...  Read full blog post.

TrkB: Docking for Neurotrophins and Beyond.
Tropomyosin receptor kinase B (TrkB) is a member of the Trk receptor tyrosine kinases family consisting of TrkA, TrkB and TrkC. The sequence of these family members is highly conserved. TrK's are activated by several neurotrophins, which are small pro...  Read full blog post.

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Bioinformatics

Gene Symbol NTRK3