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TR alpha/NR1A1/Thyroid Hormone Receptor alpha Antibody (1718)

Name: TR alpha/NR1A1/Thyroid Hormone Receptor alpha Antibody (1718)
Brand: Novus Biologicals
SKU: NB200-318
Price: 399 USD

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Western Blot: TR alpha/NR1A1/Thyroid Hormone Receptor alpha Antibody (1718) [NB200-318] - Western blot analysis of Thyroid Hormone Receptor alpha in brain lysate using NB200-318 at 1:1000.

Western Blot: TR alpha/NR1A1/Thyroid Hormone Receptor alpha Antibody (1718) [NB200-318] - Detection of human TH Receptor alpha 1 and alpha 2 using NB 200-318.

Western Blot: TR alpha/NR1A1/Thyroid Hormone Receptor alpha Antibody (1718) [NB200-318] - Western blot of rat hippocampal lysate showing specific immunolabeling of the ~50k TR-alpha-1 and the ~58k TR-alpha-2 protein.

Product Details

Summary

Reactivity	Hu, Rt, Mu, Ca, PmSpecies Glossary
Applications	WB
Clone	1718
Clonality	Monoclonal
Host	Mouse
Conjugate	Unconjugated

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TR alpha/NR1A1/Thyroid Hormone Receptor alpha Antibody (1718) Summary

Immunogen	Synthetic peptide corresponding to amino acid residues from the N-terminal region conjugated to KLH. Accession # P10827
Specificity	Specific for endogenous levels of the ~50 kDa TR-alpha1 and the ~58 kDa TR-alpha2 proteins.
Predicted Species	Mouse (100%), Canine (100%), Primate (100%). Backed by our 100% Guarantee.
Isotype	IgG2a
Clonality	Monoclonal
Host	Mouse
Gene	THRA
Purity	Protein G purified
Innovator's Reward	Test in a species/application not listed above to receive a full credit towards a future purchase. Learn about the Innovator's Reward

Applications/Dilutions

Dilutions	Western Blot 1:1000
Application Notes	The investigator should determine the optimal working dilution for a specific application.
Theoretical MW	50 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

It is anticipated that the antibody will react with canine, mouse and non-human primates based on the fact that these species have 100% homology with the amino acid sequence used as antigen.

Packaging, Storage & Formulations

Storage	Store at -20C. Avoid freeze-thaw cycles.
Buffer	10mM HEPES (pH 7.5), 0.15M NaCl, 0.1 mg/ml BSA and 50% Glycerol
Preservative	No Preservative
Purity	Protein G purified

Alternate Names for TR alpha/NR1A1/Thyroid Hormone Receptor alpha Antibody (1718)

AR7
c-ERBA-1
c-erbA-alpha
EAR7
EAR-7
EAR-7.1/EAR-7.2
ERBA
ERBA1thyroid hormone receptor, alpha (avian erythroblastic leukemia viral (v-erb-a)oncogene homolog)
ERBA-related 7
MGC000261
MGC43240
NR1A 1
NR1A1
NR1A1THRA3
Nuclear receptor subfamily 1 group A member 1
THRA
THRA1ERB-T-1
THRA2
thyroid hormone receptor alpha
thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a)oncogene homolog, avian)
TR alpha
triiodothyronine receptor
v-ErbA1
V-erbA-related protein 7

Background

Thyroid hormones regulate general metabolism and normal cellular growth and development. These actions are regulated by the thyroid hormone receptor (TR), a ligand-dependent transcriptional factor. At least two genes and several isoforms encode TR. Recent studies have implicated a role of TRs in thyroid hormone-induced apoptosis in larval tissues and proliferation of adult cell types (1-3).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol	THRA
Uniprot	P10827(Human)

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At	=	A. thaliana	SyHa	=	Golden Syrian Hamster
All	=	All Species	Ha	=	Hamster
An	=	Animal	Hu	=	Human
ArHa	=	Armenian Hamster	I	=	Insect
Av	=	Avian	Ll	=	Llama
Bb	=	Baboon	Ma	=	Mammal
Ba	=	Bacteria	Mk	=	Monkey
Bv	=	Bovine	Mu	=	Mouse
Ca	=	Canine	Multi	=	Multi-species
Ce	=	C. Elegans	NA	=	Non-species specific
Ch	=	Chicken	Or	=	Orangutan
ChHa	=	Chinese Hamster	Pl	=	Plant
Cm	=	Cynomolgus Monkey	Pm	=	Primate
Do	=	Donkey	Po	=	Porcine
Dr	=	Drosophilia	Rb	=	Rabbit
Ec	=	E. Coli	Rt	=	Rat
Eq	=	Equine	RM	=	Rhesus Macaque
Fe	=	Feline	Sh	=	Sheep
Ft	=	Ferret	Vb	=	Vertebrate
Fi	=	Fish	Vi	=	Virus
Fu	=	Fungi	Xp	=	Xenopus
Ge	=	Gerbil	Ye	=	Yeast
GP	=	Guinea Pig	Ze	=	Zebrafish
Gt	=	Goat

TR alpha/NR1A1/Thyroid Hormone Receptor alpha Antibody (1718)

Species Glossary

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Product Details

Order Details

TR alpha/NR1A1/Thyroid Hormone Receptor alpha Antibody (1718) Summary

Applications/Dilutions

Reactivity Notes

Packaging, Storage & Formulations

Alternate Names for TR alpha/NR1A1/Thyroid Hormone Receptor alpha Antibody (1718)

Background

Limitations

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Publications for TR alpha/NR1A1/Thyroid Hormone Receptor alpha Antibody (NB200-318) (0)

Reviews for TR alpha/NR1A1/Thyroid Hormone Receptor alpha Antibody (NB200-318) (0)

Product General Protocols

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FAQs for TR alpha/NR1A1/Thyroid Hormone Receptor alpha Antibody (NB200-318) (0)

Secondary Antibodies

Isotype Controls

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Research Areas for TR alpha/NR1A1/Thyroid Hormone Receptor alpha Antibody (NB200-318)

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