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SHC2 Antibody

Images

 
Western Blot: SHC2 Antibody [NBP1-87076] - Lane 1: Marker [kDa] 229, 112, 84, 48, 32, 27, 17. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp. Lane 4: Human plasma (IgG/HSA depleted). Lane 5: Human ...read more
Immunohistochemistry-Paraffin: SHC2 Antibody [NBP1-87076] - Staining of human prostate shows moderate cytoplasmic positivity in glandular cells.
Immunohistochemistry-Paraffin: SHC2 Antibody [NBP1-87076] - Staining of human cerebral cortex shows moderate cytoplasmic positivity in neurons.
Immunohistochemistry-Paraffin: SHC2 Antibody [NBP1-87076] - Staining of human lymph node shows very weak cytoplasmic positivity in germinal center cells as expected.
Immunohistochemistry-Paraffin: SHC2 Antibody [NBP1-87076] - Staining of human pancreas shows moderate cytoplasmic positivity in exocrine glandular cells.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

SHC2 Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: EHLYVNTQGLDAPEPEDSPKKDLFDMRPFEDALKLHECSVAAGVTAAPLPLEDQWPSPPTRRAPVAPTEEQLRQEPWYHGRMSRRAAERMLRADGD
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SHC2
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50 - 1:200
  • Western Blot 0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
SHC2 Protein (NBP1-87076PEP)

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (82%), Rat (85%)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for SHC2 Antibody

  • neuronal Shc adaptor homolog
  • Protein Sck
  • SCKSH2 domain protein C2
  • SHC (Src homology 2 domain containing) transforming protein 2
  • SHCBSHC-transforming protein B
  • SHC-transforming protein 2
  • SLI
  • Src homology 2 domain-containing-transforming protein C2

Background

Signaling adapter that couples activated growth factor receptors to signaling pathway in neurons. Involved in the signal transduction pathways of neurotrophin-activated Trk receptors in cortical neurons

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

Additional SHC2 Products

Array NBP1-87076

Research Areas for SHC2 Antibody (NBP1-87076)

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Blogs on SHC2

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Bioinformatics

Gene Symbol SHC2