Immunohistochemistry-Paraffin: Semaphorin 7A Antibody [NBP1-86555] - Staining of human placenta shows moderate to strong membranous positivity in trophoblastic cells.
Orthogonal Strategies: Immunohistochemistry-Paraffin: Semaphorin 7A Antibody [NBP1-86555] - Staining in human testis and skeletal muscle tissues.. Corresponding SEMA7A RNA-seq data are presented for the same ...read more
Immunohistochemistry-Paraffin: Semaphorin 7A Antibody [NBP1-86555] - Staining of human cerebral cortex shows moderate to strong membranous positivity in neurons.
Immunohistochemistry-Paraffin: Semaphorin 7A Antibody [NBP1-86555] - Staining of human testis shows moderate to strong membranous positivity in cells in seminiferous ducts.
Immunohistochemistry-Paraffin: Semaphorin 7A Antibody [NBP1-86555] - Staining of human skeletal muscle shows no positivity in myocytes as expected.
This antibody was developed against Recombinant Protein corresponding to amino acids: QDRVDFGQTEPHTVLFHEPGSSSVWVGGRGKVYLFDFPEGKNASVRTVNIGSTKGSCLDKRDCENYITLLERRSEGLLACGTNARHPSCWNLVNGTVVPLGEMRGYAPFSPDENSLVLFEGD
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SEMA7A
Purity
Immunogen affinity purified
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required for central and peripheral axon growth and is required for proper axon tract formation during embryonic development. Semaphorin 7a is also involved in modulating immune function. Semaphorin 7a expression is highest in the brain and increases in late embryonic and postnatal stages. The Semaphorins constitute a large family of secreted and membrane-tethered cell signaling molecules. They have functions in neural development, immunology, cardiac growth, vascular development, lung morphogenesis and axial bone patterning. Semaphorins are defined by the presence of a conserved Sema domain at the N-terminus. These proteins can be classified into eight classes depending on their structure and species origin. Classes 3 through 7 are found in vertebrates; class 3 are secreted, class 7 are GPI-anchored, and class 4 through 6 are transmembrane proteins.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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