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ROR gamma/RORC/NR1F3 Antibody (4G419) [PE]

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Flow Cytometry: ROR gamma/RORC/NR1F3 Antibody (4G419) [PE] [NBP2-24452] - Intracellular analysis of RORgamma in human lymphocytes using 10 ul (0.25 ug) of ROR gamma antibody. Shaded histogram represents cells without ...read more

Product Details

Summary
Reactivity Hu, Mu, Rt, PmSpecies Glossary
Applications Flow
Clone
4G419
Clonality
Monoclonal
Host
Mouse
Conjugate
PE

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ROR gamma/RORC/NR1F3 Antibody (4G419) [PE] Summary

Immunogen
A portion of amino acids 1-50 of human ROR gamma was used as the immunogen.
Predicted Species
Primate (96%). Backed by our 100% Guarantee.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
RORC
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 1ul/1 million cells
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Publications
Read Publication using NBP2-24452.

Reactivity Notes

Rat reactivity reported in scientific literature (PMID: 22110656).

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Alternate Names for ROR gamma/RORC/NR1F3 Antibody (4G419) [PE]

  • MGC129539
  • NR1F3
  • Nuclear receptor ROR gamma
  • Nuclear receptor ROR-gamma
  • Nuclear receptor RZR gamma
  • Nuclear receptor RZR-gamma
  • Nuclear receptor subfamily 1 group F member 3
  • RAR-Related Orphan Nuclear Receptor Variant 2
  • RAR-related orphan receptor C
  • RAR-related orphan receptor gamma
  • retinoic acid-binding receptor gamma
  • retinoid-related orphan receptor gamma
  • Retinoid-related orphan receptor-gamma
  • ROR gamma
  • RORC
  • RORG
  • RORGMGC129539
  • RZRG
  • RZRGRZR-GAMMA
  • TOR

Background

ROR gamma/RORC/NR1F3, aka RAR Orphan Receptor gamma, is a Nuclear Receptor 1 Thyroid Hormone-Like receptor containing a short A-T rich sequence follow by a single core motif half-site 5'-AGGTCA-3'. RORC is a key regulator of thymopoiesis, bone metabolism, T-cell apoptosis, and lymphoid organogenesis. NR1F3 regulates intrinsic transcriptional functions. Unlike other major nuclear receptors, RORC binds as a monomer to hormone response elements and is documented in mouse thymus, adipose, bone, skeletal muscle, liver, kidney, and human skeletal muscle. An N-terminal isoform of ROR gamma, ROR gamma T, inhibits Fas ligand expression and cytokine secretion in immature thymocytes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for ROR gamma/RORC/NR1F3 Antibody (NBP2-24452)(1)

We have publications tested in 1 confirmed species: Rat.


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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for ROR gamma/RORC/NR1F3 Antibody (NBP2-24452). (Showing 1 - 5 of 5 FAQ).

  1. Does ROR gamma/RORC/NR1F3 antibodies comes in lyophilized form?
    • Yes, we have 3 RORC antibodies delivere in lyophilized form: MAB61091, MAB61092, MAB6109.
  2. What the theoretical molecular weight for ROR gamma/RORC/NR1F3 antibodies?
    • The TMW of ROR gamma/RORC/NR1F3 antibodies is approximately 56 - 60.
  3. What is the immunogen sequence of this ROR gamma/RORC/NR1F3 antibody?
    • A sequence from amino acids 1 - 50 of Human ROR gamma.
  4. Please can you confirm the concentration and volume for a 100 test unit of NBP2-24452 lot number A-2-031516-F.
    • The concentration for our product NBP2-24452 Lot: A-2-031516-F is 1.0mg/ml.
  5. Please can you confirm the concentration and volume for a 100 test unit of NBP2-24452 lot number A-2-031516-F.
    • The concentration for our product NBP2-24452 Lot: A-2-031516-F is 1.0mg/ml.

Secondary Antibodies

 

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Bioinformatics

Gene Symbol RORC