I was wondering if you know of any blocking antibodies against IL-6 or VEGF-C that can be used in cell culture to quench these cytokines?

Name: Rat IL-6 DuoSet ELISA, 15 Plate
Brand: Novus Biologicals
SKU: DY506
Price: 435 USD

We have no antibodies that are currently known to show blocking antibodies to VEGF-C. Please see this link to our IL-6 antibodies with blocking/neutralizing activity can be found at this link.

Novus Biologicals products are now on bio-techne.com

Rat IL-6 DuoSet ELISA, 15 Plate

(95 Publications)

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Summary

Reactivity	RtSpecies Glossary
Applications	ELISA
Conjugate	Biotin

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Rat IL-6 DuoSet ELISA, 15 Plate Summary

Assay Type	Solid Phase Sandwich ELISA
Inter-Assay	See PDF Datasheet for details
Intra-Assay	See PDF Datasheet for details
Spike Recovery	See PDF Datasheet for details
Sample Volume	See PDF Datasheet for details
Gene	Il6

Applications/Dilutions

Dilutions

ELISA

Application Notes

No significant interference observed with available related molecules.

Publications

Read Publications using
DY506 in the following applications:

ELISA Capture
1 publication

Packaging, Storage & Formulations

Storage

Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Rat IL-6 DuoSet ELISA, 15 Plate

B-cell differentiation factor
B-cell stimulatory factor 2
BSF2
BSF-2
CDF
CTL differentiation factor
HSF
hybridoma growth factor
IFNB2
IFN-beta-2
IL6
IL-6
Interferon beta-2
interleukin 6 (interferon, beta 2)
interleukin BSF-2
interleukin-6
MGI-2A

Background

IL-6 (Interleukin-6) is a pleiotropic cytokine that acts in the acute phase reaction, inflammation, hematopoiesis, bone metabolism, and cancer progression. It contributes to chronic inflammation in obesity, insulin resistance, inflammatory bowel disease, arthritis, sepsis, and atherosclerosis. IL-6 signals through a receptor complex of IL-6 R alpha and gp130. gp130 is also a component of the receptors for CLC, CNTF, CT-1, IL-11, IL-27, LIF, and OSM. Soluble forms of IL-6 R alpha are generated by both alternative splicing and proteolytic cleavage. In a mechanism known as trans-signaling, complexes of soluble IL-6 and IL-6 R alpha elicit responses from gp130-expressing cells that lack cell surface IL-6 R alpha.

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Rat IL-6 DuoSet
ELISA, 15 Plate

DY506

Species: Rt

Applications: ELISA

Publications for IL-6 (DY506)(95)

We have publications tested in 2 confirmed species: Mouse, Rat.

We have publications tested in 1 application: ELISA Capture.

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ELISA Capture

(1)

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Mouse

(2)

Rat

(93)

All Species

Showing Publications 1 - 10 of 95. Show All 95 Publications.

Publications using DY506	Applications	Species
Anttila, JE;Mattila, OS;Liew, HK;Mätlik, K;Mervaala, E;Lindholm, P;Lindahl, M;Lindsberg, PJ;Tseng, KY;Airavaara, M; MANF protein expression is upregulated in immune cells in the ischemic human brain and systemic recombinant MANF delivery in rat ischemic stroke model demonstrates anti-inflammatory effects Acta neuropathologica communications 2024-01-16 [PMID: 38229173] (Rat)		Rat
Sangweni, NF;Gabuza, K;van Aarde, R;Mabasa, L;van Vuuren, D;Huisamen, B;Barry, R;Johnson, R; Doxorubicin-Induced Cardiomyopathy: A Preliminary Study on the Cardioprotective Benefits of 7-Hydroxyflavanone International journal of molecular sciences 2023-10-20 [PMID: 37895075] (Rat)		Rat
Xiao, Q;Chen, YH;Chen, YL;Chien, YS;Hsieh, LH;Shirakawa, H;Yang, SC; Potential Benefits of Epidermal Growth Factor for Inhibiting Muscle Degrative Markers in Rats with Alcoholic Liver Damage International journal of molecular sciences 2023-05-16 [PMID: 37240190] (Rat)		Rat
Farahzadi, R;Fathi, E;Mesbah-Namin, SA;Vietor, I; Granulocyte differentiation of rat bone marrow resident C-kit+ hematopoietic stem cells induced by mesenchymal stem cells could be considered as new option in cell-based therapy Regenerative therapy 2023-06-01 [PMID: 37206538] (Rat)		Rat
FL Haddad, C De Oliveir, S Schmid Investigating behavioral phenotypes related to autism spectrum disorder in a gene-environment interaction model of Cntnap2 deficiency and Poly I:C maternal immune activation Frontiers in Neuroscience, 2023-03-14;17(0):1160243. 2023-03-14 [PMID: 36998729] (Rat)		Rat
SK Tirunavall, M Kuncha, R Sistla, SB Andugulapa Targeting TGF-beta/periostin signaling by sesamol ameliorates pulmonary fibrosis and improves lung function and survival The Journal of nutritional biochemistry, 2023-03-21;0(0):109294. 2023-03-21 [PMID: 36948431] (Rat)		Rat
NA Lage, MRB de Paiva, DV Vasconcelo, RR Machado, SL Fialho, A Silva-Cunh Efficacy and Safety Evaluation of Mometasone Furoate in Treating Ocular Inflammation Pharmaceutics, 2023-01-05;15(1):. 2023-01-05 [PMID: 36678822] (Rat)		Rat
L Li, ZC Yao, A Parian, YH Yang, J Chao, J Yin, KJ Salimian, SK Reddy, A Zaheer, SL Gearhart, HQ Mao, FM Selaru A nanofiber-hydrogel composite improves tissue repair in a rat model of Crohn's disease perianal fistulas Science Advances, 2023-01-04;9(1):eade1067. 2023-01-04 [PMID: 36598982] (Rat)		Rat
DF Baggio, FMR da Luz, RV Lopes, LEN Ferreira, EI Araya, JG Chichorro Sex dimorphism in Resolvin D5-induced analgesia in rat models of trigeminal pain The journal of pain, 2022-12-28;0(0):. 2022-12-28 [PMID: 36584931] (Rat)		Rat
C Neu, Y Thiele, F Horr, C Beckers, N Frank, G Marx, L Martin, S Kraemer, E Zechendorf DAMPs Released from Proinflammatory Macrophages Induce Inflammation in Cardiomyocytes via Activation of TLR4 and TNFR International Journal of Molecular Sciences, 2022-12-08;23(24):. 2022-12-08 [PMID: 36555168] (Rat)		Rat
I Klein, J Boenert, F Lange, B Christense, MK Wassermann, MHJ Wiesen, DN Olschewski, M Rabenstein, C Müller, HC Lehmann, GR Fink, M Schroeter, MA Rueger, SU Vay Glia from the central and peripheral nervous system are differentially affected by paclitaxel chemotherapy via modulating their neuroinflammatory and neuroregenerative properties Frontiers in Pharmacology, 2022-11-02;13(0):1038285. 2022-11-02 [PMID: 36408236] (Rat)		Rat
RL Jayaraj, S Azimullah, KA Parekh, SK Ojha, R Beiram Effect of citronellol on oxidative stress, neuroinflammation and autophagy pathways in an in vivo model of Parkinson's disease Heliyon, 2022-11-03;8(11):e11434. 2022-11-03 [PMID: 36387498] (Rat)		Rat
D Dominguini, M Michels, LB Wessler, EL Streck, T Barichello, F Dal-Pizzol Mitochondrial protective effects caused by the administration of mefenamic acid in sepsis Journal of Neuroinflammation, 2022-11-04;19(1):268. 2022-11-04 [PMID: 36333747] (Rat)		Rat
R Li, S Bhandari, I Martinez-Z, JA Bruun, I Urbarova, B Smedsrød, J Simón-Sant, KK Sørensen Changes in the proteome and secretome of rat liver sinusoidal endothelial cells during early primary culture and effects of dexamethasone PLoS ONE, 2022-09-02;17(9):e0273843. 2022-09-02 [PMID: 36054185] (Rat)		Rat
M Adeel, CC Chen, BS Lin, HC Chen, JC Liou, YT Li, CW Peng Safety of Special Waveform of Transcranial Electrical Stimulation (TES): In Vivo Assessment International Journal of Molecular Sciences, 2022-06-20;23(12):. 2022-06-20 [PMID: 35743291] (Rat)		Rat
R Shvartsur, G Agam, S Uzzan, AN Azab Low-Dose Aspirin Augments the Anti-Inflammatory Effects of Low-Dose Lithium in Lipopolysaccharide-Treated Rats Pharmaceutics, 2022-04-20;14(5):. 2022-04-20 [PMID: 35631487] (Rat)		Rat
SB Silva, K Honorato-S, SP Costa, TE Domingues, TMM da Cruz, CM Rodrigues, KB Costa, JM Dos Santos, VK da Silva L, TP Gaiad, AP Santos, MF Dias-Peixo, CC Coimbra, AM Dos Reis, RE Szawka, PHS Figueiredo, HS Costa, MX Oliveira, VA Mendonça, ACR Lacerda The superior beneficial effects of exercise training versus hormone replacement therapy on skeletal muscle of ovariectomized rats Scientific Reports, 2022-05-24;12(1):8764. 2022-05-24 [PMID: 35610295] (Rat)		Rat
A Sharma, K Sanjeev, VMJ Selvanatha, M Sekar, N Harikrishn The evaluation of cytotoxicity and cytokine IL-6 production of root canal sealers with and without the incorporation of simvastatin: an invitro study BMC Oral Health, 2022-01-11;22(1):6. 2022-01-11 [PMID: 35012572] (Mouse)		Mouse
MJ Jeong, S Jeon, HS Yu, WS Cho, S Lee, D Kang, Y Kim, YJ Kim, SY Kim Exposure to Nickel Oxide Nanoparticles Induces Acute and Chronic Inflammatory Responses in Rat Lungs and Perturbs the Lung Microbiome International Journal of Environmental Research and Public Health, 2022-01-04;19(1):. 2022-01-04 [PMID: 35010784] (Rat)		Rat
D Galleguill, Q Wang, N Steinberg, A Zaidi, G Shrivastav, K Dhami, GC Daskhan, EN Schmidt, Z Dworsky-Fr, F Giuliani, M Churchward, C Power, K Todd, A Taylor, MS Macauley, S Sipione Anti-inflammatory role of GM1 and other gangliosides on microglia Journal of Neuroinflammation, 2022-01-06;19(1):9. 2022-01-06 [PMID: 34991625] (Rat)		Rat
A Jung, SH Kim, JY Yang, J Jeong, JK Lee, JH Oh, JH Lee Effect of Pulmonary Inflammation by Surface Functionalization of Zinc Oxide Nanoparticles Toxics, 2021-12-06;9(12):. 2021-12-06 [PMID: 34941770] (Rat)		Rat
ME Brien, K Hughes, S Girard Prenatal administration of IL-1Ra attenuate the neurodevelopmental impacts following non-pathogenic inflammation during pregnancy Scientific Reports, 2021-12-03;11(1):23404. 2021-12-03 [PMID: 34862457] (Rat)		Rat
ACA da Silva, JS Severo, BLB Dos Santos, PHM Mendes, LMS Nobre, AP de Oliveir, FCS Ferreira, JVR Medeiros, RC Lima-Junio, A Havt, RC Palheta-Ju, AA Dos Santos, M Tolentino Moderate Physical Exercise Activates ATR2 Receptors, Improving Inflammation and Oxidative Stress in the Duodenum of 2K1C Hypertensive Rats Frontiers in Physiology, 2021-10-14;12(0):734038. 2021-10-14 [PMID: 34777003] (Rat)		Rat
H Peng, BT Harvey, CI Richards, K Nixon Neuron-Derived Extracellular Vesicles Modulate Microglia Activation and Function Biology, 2021-09-22;10(10):. 2021-09-22 [PMID: 34681047] (Rat)		Rat
Q Xiao, YH Chen, SA Pratama, YL Chen, H Shirakawa, HC Peng, SC Yang The Prophylactic Effects of Glutamine on Muscle Protein Synthesis and Degradation in Rats with Ethanol-Induced Liver Damage Nutrients, 2021-08-14;13(8):. 2021-08-14 [PMID: 34444950] (Rat)		Rat
M Guibourden, H El Khayat, N Djekkoun, H Khorsi-Cau, V Bach, PM Anton, J Gay-Quéhei Programming of intestinal homeostasis in male rat offspring after maternal exposure to chlorpyrifos and/or to a high fat diet Scientific Reports, 2021-06-01;11(1):11420. 2021-06-01 [PMID: 34075131] (Rat)		Rat
SE Huang, E Sulistyowa, YY Chao, BN Wu, ZK Dai, JH Hsu, JL Yeh In Vitro Evaluation of the Anti-Inflammatory Effect of KMUP-1 and In Vivo Analysis of Its Therapeutic Potential in Osteoarthritis Biomedicines, 2021-05-28;9(6):. 2021-05-28 [PMID: 34071594] (Mouse)		Mouse
F ?aja, D Stakheev, O Chernyavsk, L Kubinová, J K?ížan, J Dvo?ák, P Rossmann, R Št?pánková, P Makovický, P Makovický, V Vymetalkov, P Sou?ek, P Vodi?ka, L Vodi?ková, M Levý, LE Vannucci Local Immune Changes in Early Stages of Inflammation and Carcinogenesis Correlate with the Collagen Scaffold Changes of the Colon Mucosa Cancers, 2021-05-18;13(10):. 2021-05-18 [PMID: 34070183] (Rat)		Rat
S Schilling, B Chausse, HO Dikmen, F Almouhanna, JO Hollnagel, A Lewen, O Kann TLR2- and TLR3-activated microglia induce different levels of neuronal network dysfunction in a context-dependent manner Brain, Behavior, and Immunity, 2021-05-17;0(0):. 2021-05-17 [PMID: 34015428] (Rat)		Rat
SJB Jesudasan, SJ Gupta, MA Churchward, KG Todd, IR Winship Inflammatory Cytokine Profile and Plasticity of Brain and Spinal Microglia in Response to ATP and Glutamate Frontiers in Cellular Neuroscience, 2021-04-06;15(0):634020. 2021-04-06 [PMID: 33889075] (Rat)		Rat
N Perez Diaz, LA Lione, V Hutter, LS Mackenzie Co-Incubation with PPAR&beta/&delta Agonists and Antagonists Modeled Using Computational Chemistry: Effect on LPS Induced Inflammatory Markers in Pulmonary Artery International Journal of Molecular Sciences, 2021-03-19;22(6):. 2021-03-19 [PMID: 33808880] (Rat)		Rat
VGB Brito, MS Patrocinio, MCL Sousa, AEA Barreto, SCT Frasnelli, VS Lara, CF Santos, SHP Oliveira Mast cells contribute to alveolar bone loss in Spontaneously Hypertensive Rats with periodontal disease regulating cytokines production PLoS ONE, 2021-03-04;16(3):e0247372. 2021-03-04 [PMID: 33661916] (Rat)		Rat
JH He, RP Liu, YM Peng, Q Guo, LB Zhu, YZ Lian, BL Hu, HH Fan, X Zhang, JH Zhu Differential and paradoxical roles of new-generation antidepressants in primary astrocytic inflammation Journal of Neuroinflammation, 2021-02-18;18(1):47. 2021-02-18 [PMID: 33602262] (Rat)		Rat
JNB Pereira, GM Murata, FT Sato, AR Marosti, CRO Carvalho, R Curi Small intestine remodeling in male Goto-Kakizaki rats Physiological Reports, 2021-02-01;9(3):e14755. 2021-02-01 [PMID: 33580916] (Rat)		Rat
SM Davis, LA Collier, SJ Messmer, KR Pennypacke The Poststroke Peripheral Immune Response Is Differentially Regulated by Leukemia Inhibitory Factor in Aged Male and Female Rodents Oxidative Medicine and Cellular Longevity, 2020-12-10;2020(0):8880244. 2020-12-10 [PMID: 33376583] (Rat)		Rat
H Javed, MFN Meeran, S Azimullah, L Bader Eddi, VD Dwivedi, NK Jha, S Ojha &alpha-Bisabolol, a Dietary Bioactive Phytochemical Attenuates Dopaminergic Neurodegeneration through Modulation of Oxidative Stress, Neuroinflammation and Apoptosis in Rotenone-Induced Rat Model of Parkinson's disease Biomolecules, 2020-10-08;10(10):. 2020-10-08 [PMID: 33049992] (Rat)		Rat
YL Chen, H Shirakawa, NS Lu, HC Peng, Q Xiao, SC Yang Impacts of fish oil on the gut microbiota of rats with alcoholic liver damage J. Nutr. Biochem., 2020-09-11;86(0):108491. 2020-09-11 [PMID: 32920090] (Rat)		Rat
M Defaye, C Nourrisson, E Baudu, A Lashermes, M Meynier, M Meleine, I Wawrzyniak, V Bonnin, J Barbier, B Chassaing, C Godfraind, A Gelot, N Barnich, D Ardid, M Bonnet, F Delbac, FA Carvalho, P Poirier Fecal dysbiosis associated with colonic hypersensitivity and behavioral alterations in chronically Blastocystis-infected rats Sci Rep, 2020-06-04;10(1):9146. 2020-06-04 [PMID: 32499543] (Rat)		Rat
AM Baratta, NR Kanyuch, CA Cole, H Valafar, J Deslaurier, A Pocivavsek Acute sleep deprivation during pregnancy in rats: Rapid elevation of placental and fetal inflammation and kynurenic acid Neurobiol Stress, 2019-12-14;12(0):100204. 2019-12-14 [PMID: 32258253] (Rat)		Rat
J Cui, X Guo, Q Li, N Song, J Xie Hepcidin-to-Ferritin Ratio Is Decreased in Astrocytes With Extracellular Alpha-Synuclein and Iron Exposure Front Cell Neurosci, 2020-03-10;14(0):47. 2020-03-10 [PMID: 32210768] (Rat)		Rat
P Siriarchav, MC Kruger, MR Miller, HS Tian, FM Wolber The Preventive Effects of Greenshell Mussel (Perna canaliculus) on Early-Stage Metabolic Osteoarthritis in Rats with Diet-Induced Obesity Nutrients, 2019-07-15;11(7):. 2019-07-15 [PMID: 31311115] (Rat)		Rat
AB Silva Risc, NIP Neto, K Gascho, M Carnier, DA de Miranda, FP Silva, VT Boldarine, M Seelaender, EB Ribeiro, LM Oyama, CM Oller do N A diet including xanthan gum triggers a pro-inflammatory response in Wistar rats inoculated with Walker 256 cells PLoS ONE, 2019-06-18;14(6):e0218567. 2019-06-18 [PMID: 31211796] (Rat)		Rat
S Chapman, E Grauer, R Gez, I Egoz, S Lazar Time dependent dual effect of anti-inflammatory treatments on sarin-induced brain inflammation: suggested role of prostaglandins Neurotoxicology, 2019-05-13;0(0):. 2019-05-13 [PMID: 31095963] (Rat)		Rat
P Valaskova, A Dvorak, M Lenicek, K Zizalova, N Kutinova-C, J Zelenka, M Cahova, L Vitek, L Muchova Hyperbilirubinemia in Gunn Rats is Associated with Decreased Inflammatory Response in LPS-Mediated Systemic Inflammation Int J Mol Sci, 2019-05-09;20(9):. 2019-05-09 [PMID: 31075981] (Rat)		Rat
AB Santamarin, G Jamar, LV Mennitti, DA Ribeiro, CM Cardoso, VV de Rosso, LM Oyama, LP Pisani Polyphenols-Rich Fruit (Euterpe edulis Mart.) Prevents Peripheral Inflammatory Pathway Activation by the Short-Term High-Fat Diet Molecules, 2019-04-27;24(9):. 2019-04-27 [PMID: 31035535] (Rat)		Rat
Y van der Me, AE Faust, ET Sakalli, CC Westrick, G Hussey, IP Conner, VLN Fu, SF Badylak, MB Steketee Matrix-bound nanovesicles prevent ischemia-induced retinal ganglion cell axon degeneration and death and preserve visual function Sci Rep, 2019-03-05;9(1):3482. 2019-03-05 [PMID: 30837658] (Rat)		Rat
J Wang, J Chen, H Jin, D Lin, Y Chen, X Chen, B Wang, S Hu, Y Wu, Y Wu, Y Zhou, N Tian, W Gao, X Wang, X Zhang BRD4 inhibition attenuates inflammatory response in microglia and facilitates recovery after spinal cord injury in rats J. Cell. Mol. Med., 2019-02-26;0(0):. 2019-02-26 [PMID: 30809946] (Rat)		Rat
CA Barboza, AR Fukushima, N Carrozzi, JF Machi, PMM Dourado, CT Mostarda, MC Irigoyen, L Nathanson, M Morris, EC Caperuto, B Rodrigues Cholinergic Stimulation by Pyridostigmine Bromide Before Myocardial Infarction Prevent Cardiac and Autonomic Dysfunction Sci Rep, 2019-02-21;9(1):2481. 2019-02-21 [PMID: 30792425] (Rat)		Rat
SJ Lee, H Wang, SH Ahn, MK Son, GH Hyun, SJ Yoon, J Lee, JH Park, J Lim, SS Hong, SW Kwon Metabolomics Approach Based on Multivariate Techniques for Blood Transfusion Reactions Sci Rep, 2019-02-11;9(1):1740. 2019-02-11 [PMID: 30741955] (Rat)		Rat
D Morales-Ca, M Callejo, B Barreira, G Mondejar-P, S Esquivel-R, S Ramos, MÁ Martín, A Cogolludo, L Moreno, F Perez-Vizc Elevated pulmonary arterial pressure in Zucker diabetic fatty rats PLoS ONE, 2019-01-28;14(1):e0211281. 2019-01-28 [PMID: 30689673] (Rat)		Rat
WS Tan, P Arulselvan, SF Ng, CN Mat Taib, MN Sarian, S Fakurazi Improvement of diabetic wound healing by topical application of Vicenin-2 hydrocolloid film on Sprague Dawley rats BMC Complement Altern Med, 2019-01-17;19(1):20. 2019-01-17 [PMID: 30654793] (Rat)		Rat
HM Wilson, L Cheyne, PAJ Brown, K Kerr, A Hannah, J Srinivasan, N Duniak, G Horgan, DK Dawson Characterization of the Myocardial Inflammatory Response in Acute Stress-Induced (Takotsubo) Cardiomyopathy JACC Basic Transl Sci, 2018-12-31;3(6):766-778. 2018-12-31 [PMID: 30623136] (Rat)		Rat
WMT Kuwabara, CNF Yokota, R Curi, TC Alba-Loure Obesity and Type 2 Diabetes mellitus induce lipopolysaccharide tolerance in rat neutrophils Sci Rep, 2018-12-03;8(1):17534. 2018-12-03 [PMID: 30510205] (Rat)		Rat
HF Filippini, PA Scalzilli, KM Costa, RDS Freitas, MM Campos Activation of trigeminal ganglion satellite glial cells in CFA-induced tooth pulp pain in rats PLoS ONE, 2018-11-12;13(11):e0207411. 2018-11-12 [PMID: 30419075] (Rat)		Rat
RB Batacan, MJ Duncan, VJ Dalbo, GL Buitrago, AS Fenning Effect of different intensities of physical activity on cardiometabolic markers and vascular and cardiac function in adult rats fed with a high-fat high-carbohydrate diet J Sport Health Sci, 2016-08-03;7(1):109-119. 2016-08-03 [PMID: 30356452] (Rat)		Rat
SM Davis, LA Collier, ED Winford, CC Leonardo, CT Ajmo, EA Foran, TJ Kopper, JC Gensel, KR Pennypacke Leukemia inhibitory factor modulates the peripheral immune response in a rat model of emergent large vessel occlusion J Neuroinflammation, 2018-10-15;15(1):288. 2018-10-15 [PMID: 30322390] (Rat)		Rat
N Shologu, M Scully, JG Laffey, D O'Toole Human Mesenchymal Stem Cell Secretome from Bone Marrow or Adipose-Derived Tissue Sources for Treatment of Hypoxia-Induced Pulmonary Epithelial Injury Int J Mol Sci, 2018-09-30;19(10):. 2018-09-30 [PMID: 30274394] (Rat)		Rat
SU Vay, LJ Flitsch, M Rabenstein, R Rogall, S Blaschke, J Kleinhaus, N Reinert, A Bach, GR Fink, M Schroeter, MA Rueger The plasticity of primary microglia and their multifaceted effects on endogenous neural stem cells in vitro and in vivo J Neuroinflammation, 2018-08-13;15(1):226. 2018-08-13 [PMID: 30103769] (Rat)		Rat
AB Santamarin, G Jamar, LV Mennitti, VV de Rosso, HC Cesar, LM Oyama, LP Pisani The Use of Juï¿½ara (Euterpe edulis Mart.) Supplementation for Suppression of NF-?B Pathway in the Hypothalamus after High-Fat Diet in Wistar Rats Molecules, 2018-07-21;23(7):. 2018-07-21 [PMID: 30037112] (Rat)		Rat
C Chaiyasut, S Woraharn, BS Sivamaruth, N Lailerd, P Kesika, S Peerajan Lactobacillus fermentum HP3-Mediated Fermented Hericium erinaceus Juice as a Health Promoting Food Supplement to Manage Diabetes Mellitus J Evid Based Integr Med, 2018-01-01;23(0):2515690X18765. 2018-01-01 [PMID: 29619846] (Rat)		Rat
GS Bassi, L Ulloa, VR Santos, F Del Vecchi, P Delfino-Pe, GJ Rodrigues, JA Castania, FQ Cunha, HC Salgado, TM Cunha, N Garcia-Cai, A Kanashiro Cortical stimulation in conscious rats controls joint inflammation Prog. Neuropsychopharmacol. Biol. Psychiatry, 2018-03-06;0(0):. 2018-03-06 [PMID: 29522782] (Rat)		Rat
LV Mennitti, LM Oyama, AB Santamarin, CMDPO do Nascime, LP Pisani Early exposure to distinct sources of lipids affects differently the development and hepatic inflammatory profiles of 21-day-old rat offspring J Inflamm Res, 2018-01-18;11(0):11-24. 2018-01-18 [PMID: 29403301] (Rat)		Rat
YW Chien, HC Peng, YL Chen, MH Pai, HY Wang, HL Chuang, SC Yang Different Dietary Proportions of Fish Oil Regulate Inflammatory Factors but Do Not Change Intestinal Tight Junction ZO-1 Expression in Ethanol-Fed Rats Mediators Inflamm., 2017-12-13;2017(0):5801768. 2017-12-13 [PMID: 29386752] (Rat)		Rat
RK Vella, DJ Jackson, AS Fenning ?9-Tetrahydrocannabinol Prevents Cardiovascular Dysfunction in STZ-Diabetic Wistar-Kyoto Rats Biomed Res Int, 2017-10-18;2017(0):7974149. 2017-10-18 [PMID: 29181404] (Rat)		Rat
OC Bezerra, CM França, JA Rocha, GA Neves, PRM Souza, M Teixeira G, C Malfitano, TCA Loleiro, PM Dourado, S Llesuy, K de Angelis, MCC Irigoyen, L Ulloa, FM Consolim-C Cholinergic Stimulation Improves Oxidative Stress and Inflammation in Experimental Myocardial Infarction Sci Rep, 2017-10-20;7(1):13687. 2017-10-20 [PMID: 29057895] (Rat)		Rat
FM Santos-Alm, G Domingos-S, CA Meschiari, LC Fávaro, C Becari, JA Castania, A Lopes, TM Cunha, DJA Moraes, FQ Cunha, L Ulloa, A Kanashiro, GCSV Tezini, HC Salgado Carotid sinus nerve electrical stimulation in conscious rats attenuates systemic inflammation via chemoreceptor activation Sci Rep, 2017-07-24;7(1):6265. 2017-07-24 [PMID: 28740186] (Rat)		Rat
LD Almeida Ju, AEV Quaglio, CAR de Almeida, LC Di Stasi Intestinal anti-inflammatory activity of Ground Cherry (Physalis angulata L.) standardized CO2 phytopharmaceutical preparation World J. Gastroenterol., 2017-06-28;23(24):4369-4380. 2017-06-28 [PMID: 28706419] (Rat)		Rat
CC Hsu, CL Lin, IM Jou, PH Wang, JS Lee The protective role of nitric oxide-dependent innate immunosuppression in the early stage of cartilage damage in rats: Role of nitric oxide in cartilage damage Bone Joint Res, 2017-04-01;6(4):253-258. 2017-04-01 [PMID: 28450318] (Rat)		Rat
M von Chamie, L Reyes, LF Hayward, MB Brown Impact of gestational nicotine exposure on intrauterine and fetal infection in a rodent model Biol. Reprod., 2017-05-01;96(5):1071-1084. 2017-05-01 [PMID: 28419180] (ELISA Capture, Rat)	ELISA Capture	Rat
C Francioli, X Wang, R Parapanov, E Abdelnour, J Lugrin, F Gronchi, J Perentes, P Eckert, HB Ris, L Piquilloud, T Krueger, L Liaudet Pyrrolidine dithiocarbamate administered during ex-vivo lung perfusion promotes rehabilitation of injured donor rat lungs obtained after prolonged warm ischemia PLoS ONE, 2017-03-21;12(3):e0173916. 2017-03-21 [PMID: 28323904] (Rat)		Rat
KL Tsai, PC Huang, LK Wang, CH Hung, YW Chen Incline treadmill exercise suppresses pain hypersensitivity associated with the modulation of pro-inflammatory cytokines and anti-inflammatory cytokine in rats with peripheral nerve injury Neurosci. Lett, 2017-02-12;643(0):27-31. 2017-02-12 [PMID: 28215879] (Rat)		Rat
S Bettini, E Boutet-Rob, C Cartier, C Com‚ra, E Gaultier, J Dupuy, N Naud, S Tach‚, P Grysan, S Reguer, N Thieriet, M R‚fr‚giers, D ThiaudiŠre, JP Cravedi, M CarriŠre, JN Audinot, FH Pierre, L Guzylack-P, E Houdeau Food-grade TiO2 impairs intestinal and systemic immune homeostasis, initiates preneoplastic lesions and promotes aberrant crypt development in the rat colon Sci Rep, 2017-01-20;7(0):40373. 2017-01-20 [PMID: 28106049] (Rat)		Rat
Bruno Rodrigues Impact of exercise training associated to pyridostigmine treatment on autonomic function and inflammatory profile after myocardial infarction in rats Int. J. Cardiol., 2016-10-26;0(0):. 2016-10-26 [PMID: 27823896] (Rat)		Rat
Cláudia Herrera Tambeli Intra-articular blockade of P2X7 receptor reduces the articular hyperalgesia and inflammation in the knee joint synovitis especially in female rats J Pain, 2016-11-04;0(0):. 2016-11-04 [PMID: 27818192] (Rat)		Rat
DZ Hsu, PY Chu, IM Jou Enteral sesame oil therapeutically relieves disease severity in rat experimental osteoarthritis Food Nutr Res, 2016-03-30;60(0):29807. 2016-03-30 [PMID: 27032670] (Rat)		Rat
Bhushan S, Tchatalbachev S, Lu Y, Frohlich S, Fijak M, Vijayan V, Chakraborty T, Meinhardt A Differential activation of inflammatory pathways in testicular macrophages provides a rationale for their subdued inflammatory capacity. J Immunol, 2015-04-27;194(11):5455-64. 2015-04-27 [PMID: 25917085] (Rat)		Rat
Elgrabli D, Beaudouin R, Jbilou N, Floriani M, Pery A, Rogerieux F, Lacroix G Biodistribution and Clearance of TiO2 Nanoparticles in Rats after Intravenous Injection. PLoS ONE, 2015-04-24;10(4):e0124490. 2015-04-24 [PMID: 25909957] (Rat)		Rat
Baskar Jesudasan , Sam Josh, Todd , Kathryn, Winship , Ian R Reduced inflammatory phenotype in microglia derived from neonatal rat spinal cord versus brain. PLoS ONE, 2014-06-10;9(6):e99443. 2014-06-10 [PMID: 24914808] (Rat)		Rat
Samarska I, Bouma H, Buikema H, Mungroop H, Houwertjes M, Absalom A, Epema A, Henning R S1P1 receptor modulation preserves vascular function in mesenteric and coronary arteries after CPB in the rat independent of depletion of lymphocytes. PLoS ONE, 2014-05-12;9(5):e97196. 2014-05-12 [PMID: 24819611] (Rat)		Rat
Hachul A, Mennitti L, de Oliveira J, Moreno M, Okuda M, Dos Santos B, Oyama L, Ribeiro E, do Nascimento C, Pisani L Oligofructose supplementation (10%) during pregnancy and lactation does not change the inflammatory effect of concurrent trans fatty acid ingestion on 21-day-old offspring. Lipids Health Dis, 2013-05-01;12(0):59. 2013-05-01 [PMID: 23634906] (Rat)		Rat
Roddy GW, Oh JY, Lee RH, Bartosh TJ, Ylostalo J, Coble K, Rosa RH, Prockop DJ Action at a distance: systemically administered adult stem/progenitor cells (MSCs) reduce inflammatory damage to the cornea without engraftment and primarily by secretion of TNF-alpha stimulated gene/protein 6. Stem Cells, 2011-10-01;29(10):1572-9. 2011-10-01 [PMID: 21837654] (Rat)		Rat
Yamashita AS, Lira FS, Rosa JC, Paulino EC, Brum PC, Negrao CE, dos Santos RV, Batista ML, do Nascimento CO, Oyama LM, Seelaender M Depot-specific modulation of adipokine levels in rat adipose tissue by diet-induced obesity: the effect of aerobic training and energy restriction. Cytokine, 2010-08-21;52(3):168-74. 2010-08-21 [PMID: 20728374] (Rat)		Rat
Vlaar AP, Hofstra JJ, Kulik W Supernatant of stored platelets causes lung inflammation and coagulopathy in a novel in vivo transfusion model. Blood, 2010-05-17;116(8):1360-8. 2010-05-17 [PMID: 20479286] (Rat)		Rat
Barichello T, dos Santos I, Savi GD, Simoes LR, Silvestre T, Comim CM, Sachs D, Teixeira MM, Teixeira AL, Quevedo J TNF-alpha, IL-1beta, IL-6, and cinc-1 levels in rat brain after meningitis induced by Streptococcus pneumoniae. J. Neuroimmunol., 2010-03-03;221(1):42-5. 2010-03-03 [PMID: 20202693] (Rat)		Rat
Man PS, Lawrence CB Interleukin-1 mediates the anorexic and febrile actions of galanin-like Peptide. Endocrinology, 2008-07-10;149(11):5791-802. 2008-07-10 [PMID: 18617619] (Rat)		Rat
Ganesan K, Balachandran C, Manohar BM, Puvanakrishnan R Comparative studies on the interplay of testosterone, estrogen and progesterone in collagen induced arthritis in rats. Bone, 2008-06-10;43(4):758-65. 2008-06-10 [PMID: 18599392] (Rat)		Rat
Roche M, Kelly JP, O'Driscoll M, O'Driscoll M, Finn DP Augmentation of endogenous cannabinoid tone modulates lipopolysaccharide-induced alterations in circulating cytokine levels in rats. Immunology, 2008-04-03;125(2):263-71. 2008-04-03 [PMID: 18393970] (Rat)		Rat
Cicala C, Morello S, Alfieri A, Vellecco V, Marzocco S, Autore G Haemostatic imbalance following carrageenan-induced rat paw oedema. Eur. J. Pharmacol., 2007-08-14;577(1):156-61. 2007-08-14 [PMID: 17850787] (Rat)		Rat
Fernandes A, Falcao AS, Silva RF, Brito MA, Brites D MAPKs are key players in mediating cytokine release and cell death induced by unconjugated bilirubin in cultured rat cortical astrocytes. Eur. J. Neurosci., 2007-02-01;25(4):1058-68. 2007-02-01 [PMID: 17331202] (Rat)		Rat
Yang SR, Wright J, Bauter M, Seweryniak K, Kode A, Rahman I Sirtuin regulates cigarette smoke-induced proinflammatory mediator release via RelA/p65 NF-kappaB in macrophages in vitro and in rat lungs in vivo: implications for chronic inflammation and aging. Am. J. Physiol. Lung Cell Mol. Physiol., 2006-10-13;292(2):L567-76. 2006-10-13 [PMID: 17041012] (Rat)		Rat
Oprica M, Spulber SD, Aronsson AF, Post C, Winblad B, Schultzberg M The influence of kainic acid on core temperature and cytokine levels in the brain. Cytokine, 2006-09-06;35(1):77-87. 2006-09-06 [PMID: 16950633] (Rat)		Rat
Haas CS, Amin MA, Allen BB, Ruth JH, Haines GK, Woods JM, Koch AE Inhibition of angiogenesis by interleukin-4 gene therapy in rat adjuvant-induced arthritis. Arthritis Rheum., 2006-08-01;54(8):2402-14. 2006-08-01 [PMID: 16869003] (Rat)		Rat
Birrell MA, Wong S, Dekkak A, De Alba J, Haj-Yahia S, Belvisi MG Role of matrix metalloproteinases in the inflammatory response in human airway cell-based assays and in rodent models of airway disease. J. Pharmacol. Exp. Ther., 2006-05-11;318(2):741-50. 2006-05-11 [PMID: 16690722] (Rat)		Rat
Niederbichler AD, Westfall MV, Su GL, Donnerberg J, Usman A, Vogt PM, Ipaktchi KR, Arbabi S, Wang SC, Hemmila MR Cardiomyocyte function after burn injury and lipopolysaccharide exposure: single-cell contraction analysis and cytokine secretion profile. Shock, 2006-02-01;25(2):176-83. 2006-02-01 [PMID: 16525357] (Rat)		Rat
Fernandes A, Falcao AS, Silva RF, Gordo AC, Gama MJ, Brito MA, Brites D Inflammatory signalling pathways involved in astroglial activation by unconjugated bilirubin. J. Neurochem., 2006-02-10;96(6):1667-79. 2006-02-10 [PMID: 16476078] (Rat)		Rat
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I was wondering if you know of any blocking antibodies against IL-6 or VEGF-C that can be used in cell culture to quench these cytokines?
- We have no antibodies that are currently known to show blocking antibodies to VEGF-C. Please see this link to our IL-6 antibodies with blocking/neutralizing activity can be found at this link.

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Rest in Peace: Is the Receptor Interacting Protein (RIP) Kinase-3 (RIPK3) a Protector or Offender?
By Jamshed Arslan, Pharm. D., PhD. Receptor interacting protein kinases (RIPKs) in necroptosisDeath is perhaps inevitable. Cell death can be programed and immunologically silent (apoptosis), unprogrammed and inflamm... Read full blog post.

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Metabolic Syndrome: Symptoms and associated disease states
By Jamshed Arslan, Pharm. D., PhD. What is metabolic syndrome?It was 1988 when, after decades of research, Dr. GM Reaven of the Stanford University, CA, explained the relationship between four diseases:... Read full blog post.

Increased wild type FUS levels in ALS patients lead to a toxic microenvironment and motor neuron neurodegeneration
By Michalina Hanzel, PhDFUS mutations in Amyotrophic Lateral SclerosisFused in sarcoma (FUS) is a ribonucleoprotein that continuously shuttles between the nucleus and the cytoplasm to regulate pre-mRNA splicing, mRN... Read full blog post.

The role of HIF-2 alpha in the progression and therapy of clear cell renal cell carcinoma
HIF-2 alpha, also known as hypoxia-inducible factor 2, endothelial PAS domain protein-1, and member of PAS superfamily 2 is part of the HIF family of proteins. The HIF family is composed of HIF-1, HIF-2 and HIF-3, where HIF-2 is a dimeric protein ... Read full blog post.

The use of a GFP antibody for research applications in transgenic C. elegans, GFP tagged yeast and porcine model
GFP, or green fluorescent protein, is a chemiluminescent protein derived from Aequorea jellyfish that was first discovered by Osamu Shimomura. It was soon after established that the emission spectra of GFP was right around 509nm, or the ultraviol... Read full blog post.

VEGF: Vascular endothelial growth factor
VEGF is homodimeric, disulfide-linked glycoprotein cytokine that serves as the ligand for FLT1 (VEGFR-1 receptor) and FLK1 (VEGFR-2 receptor) tyrosine kinases. It is a key modulator of physiological angiogenesis, vasculogenesis, and endothelial cell g... Read full blog post.

TLR2 - I can recognize many foreign pathogens!
TLR2 is a member of the broad family of Toll-like receptors (TLR) that play an important role in pathogen recognition and innate immunity. TLRs, like other pattern recognition receptors (PRRs), recognize endogenous ligands released during cell or tiss... Read full blog post.

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At	=	A. thaliana	SyHa	=	Golden Syrian Hamster
All	=	All Species	Ha	=	Hamster
An	=	Animal	Hu	=	Human
ArHa	=	Armenian Hamster	I	=	Insect
Av	=	Avian	Ll	=	Llama
Bb	=	Baboon	Ma	=	Mammal
Ba	=	Bacteria	Mk	=	Monkey
Bv	=	Bovine	Mu	=	Mouse
Ca	=	Canine	Multi	=	Multi-species
Ce	=	C. Elegans	NA	=	Non-species specific
Ch	=	Chicken	Or	=	Orangutan
ChHa	=	Chinese Hamster	Pl	=	Plant
Cm	=	Cynomolgus Monkey	Pm	=	Primate
Do	=	Donkey	Po	=	Porcine
Dr	=	Drosophilia	Rb	=	Rabbit
Ec	=	E. Coli	Rt	=	Rat
Eq	=	Equine	RM	=	Rhesus Macaque
Fe	=	Feline	Sh	=	Sheep
Ft	=	Ferret	Vb	=	Vertebrate
Fi	=	Fish	Vi	=	Virus
Fu	=	Fungi	Xp	=	Xenopus
Ge	=	Gerbil	Ye	=	Yeast
GP	=	Guinea Pig	Ze	=	Zebrafish
Gt	=	Goat

Rat IL-6 DuoSet ELISA, 15 Plate

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