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PIEZO1 Antibody [DyLight 755]

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Product Details

Summary
Reactivity Hu, Mu, GpSpecies Glossary
Applications WB, Flow, ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
DyLight 755

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP1-78446AF350
Alexa Fluor 405
NBP1-78446AF405
Alexa Fluor 488
NBP1-78446AF488
Alexa Fluor 532
NBP1-78446AF532
Alexa Fluor 594
NBP1-78446AF594
Alexa Fluor 647
NBP1-78446AF647
Alexa Fluor 700
NBP1-78446AF700
Alexa Fluor 750
NBP1-78446AF750
Allophycocyanin
NBP1-78446APC
Biotin
NBP1-78446B
CoraFluor 1
NBP1-78446CL1
DyLight 350
NBP1-78446UV
DyLight 405
NBP1-78446V
DyLight 488
NBP1-78446G
DyLight 550
NBP1-78446R
DyLight 594
NBP1-78446DL594
DyLight 650
NBP1-78446C
DyLight 680
NBP1-78446FR
FITC
NBP1-78446F
HRP
NBP1-78446H
Janelia Fluor 525
NBP1-78446JF525
Janelia Fluor 549
NBP1-78446JF549
Janelia Fluor 585
NBP1-78446JF585
Janelia Fluor 635
NBP1-78446JF635
Janelia Fluor 646
NBP1-78446JF646
Janelia Fluor 669
NBP1-78446JF669
PE
NBP1-78446PE
PerCP
NBP1-78446PCP
Unconjugated
NBP1-78446
mFluor Violet 450 SE
NBP1-78446MFV450
mFluor Violet 500 SE
NBP1-78446MFV500
mFluor Violet 610 SE
NBP1-78446MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP1-78446
BSA Free
NBP1-78446SS
BSA Free
NBP1-78446
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PIEZO1 Antibody [DyLight 755] Summary

Immunogen
A synthetic peptide made to an internal portion of the human PIEZO1 protein (between residues 950-1000) [UniProt Q92508]
Localization
Endoplasmic reticulum membrane; Multi-pass membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane. Cell membrane; Multi-pass membrane protein.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PIEZO1
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Guinea Pig reactivity reported in scientific literature (PMID: 30324494).

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for PIEZO1 Antibody [DyLight 755]

  • FAM38A
  • KIAA0233
  • member A
  • membrane protein induced by beta-amyloid treatment
  • Mib
  • PIEZO1
  • piezo-type mechanosensitive ion channel component 1
  • Protein FAM38A

Background

PIEZO1 (piezo-type mechanosensitive ion channel component 1) plays a crucial role in epithelial cell adhesion. PIEZO1 belongs to the PIEZO family of transmembrane proteins. Mutations in Piezo1 have been tied to Xerocytosis. PIEZO1 has been studied in relation to neuronitis, Alzheimer's disease and Parkinson's disease.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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PIEZO1 Antibody
[DyLight 755]
NBP1-78446IR
PIEZO1 Antibody [DyLight 755]
Species: Hu, Mu, Gp
Applications: WB, Flow, ICC/IF, IHC

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Product General Protocols

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Video Protocols

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ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

Additional PIEZO1 Products

Array NBP1-78446IR

Research Areas for PIEZO1 Antibody (NBP1-78446IR)

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Blogs on PIEZO1.

Check out the latest blog posts on PIEZO1.
Touch Infographic: From Touch Receptors to the Brain
The body contains thousands of receptors and nerves which allow us to experience the sense of touch, also referred to as tactile perception. The somatosensory system allows organisms to perceive and decode a wide range of tactile stimuli to allow for ...  Read full blog post.
PIEZO1: A Mechanosensitive Ion Channel Protein
PIEZO1, and its close homologue PIEZO2, are mechanosensitive ion channel proteins. Mechanosensitive ion channels couple protein conformation to the mechanics of the surrounding membrane, and switch between a closed state and an open state in response ...  Read full blog post.
Read our latest blog and use the new citation tool on bio-techne.com

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Bioinformatics

Gene Symbol PIEZO1