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OX40 Ligand/TNFSF4 Antibody (R4930 (Oxelumab)) [Alexa Fluor® 532]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, B/N
Clone
R4930 (Oxelumab)
Clonality
Monoclonal
Host
Human
Conjugate
Alexa Fluor 532

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OX40 Ligand/TNFSF4 Antibody (R4930 (Oxelumab)) [Alexa Fluor® 532] Summary

Immunogen
Oxelumab binds to human OX40L, the ligand of OX40, stimulatory receptor that is expressed on activated T cells, natural killer (NK) cells and natural killer T (NKT) cells.
Specificity
Binds to human OX40L.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Human
Gene
TNFSF4
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • Block/Neutralize
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes



Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for OX40 Ligand/TNFSF4 Antibody (R4930 (Oxelumab)) [Alexa Fluor® 532]

  • CD134 ligand
  • CD134L
  • CD252 antigen
  • CD252
  • Glycoprotein Gp34
  • gp34
  • OX40 antigen ligand
  • OX40 Ligand
  • OX40L
  • OX-40L
  • OX4OL
  • TAX transcriptionally-activated glycoprotein 1
  • tax-transcriptionally activated glycoprotein 1 (34kD)
  • tax-transcriptionally activated glycoprotein 1, 34kD
  • TNFSF4
  • tumor necrosis factor (ligand) superfamily, member 4
  • tumor necrosis factor ligand superfamily member 4
  • TXGP1

Background

CD252 is a 35 kD member of the TNF superfamily also known as OX40L and CD134L. The OX40 ligand is expressed on activated B cells and antigen presenting cells. OX40 ligand interacts with OX40 antigen (CD134) expressed predominantly on activated T cells to increase proliferation and IL-2 production, and to enhance proliferation and immunoglobulin secretion in activated B cells. The RM134L antibody can inhibit OX40/OX40 ligand interactions and block the costimulatory activity of OX40L.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol TNFSF4