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OX40 Ligand/TNFSF4 Antibody (159403) [PE/Cy5.5]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
159403
Clonality
Monoclonal
Host
Mouse
Conjugate
PE/Cy5.5

Order Details

OX40 Ligand/TNFSF4 Antibody (159403) [PE/Cy5.5] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human OX40 Ligand
Gln51-Leu183
Accession # P23510
Specificity
Detects human OX40 Ligand in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human (rh) APRIL, rhBAFF, rhCD27 Ligand, recombinant mouse (rm) CD27 Ligand, rhCD30 Ligand, rmCD30 Ligand, rhCD40 Ligand, rmEDA, rhFas Ligand, rmFas Ligand, rhGITR Ligand, recombinant cotton rat TNF-alpha , rhTNF-alpha , rmTNF-alpha , recombinant porcine TNF-alpha , recombinant rat TNF-alpha , rhTRAIL, rhTRANCE, rmTRANCE, or rhVEGF is observed.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
TNFSF4
Purity
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined. For optimal results using our Tandem dyes, please avoid prolonged exposure to light or extreme temperature fluctuations. These can lead to irreversible degradation or decoupling. When staining intracellular targets, specific attention to the fixation and permeabilization steps in your flow protocol may be required. Please contact our technical support team at technical@novusbio.com if you have any questions.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark. Do not freeze.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Alternate Names for OX40 Ligand/TNFSF4 Antibody (159403) [PE/Cy5.5]

  • CD134 ligand
  • CD134L
  • CD252 antigen
  • CD252
  • Glycoprotein Gp34
  • gp34
  • OX40 antigen ligand
  • OX40 Ligand
  • OX40L
  • OX-40L
  • OX4OL
  • TAX transcriptionally-activated glycoprotein 1
  • tax-transcriptionally activated glycoprotein 1 (34kD)
  • tax-transcriptionally activated glycoprotein 1, 34kD
  • TNFSF4
  • tumor necrosis factor (ligand) superfamily, member 4
  • tumor necrosis factor ligand superfamily member 4
  • TXGP1

Background

CD252 is a 35 kD member of the TNF superfamily also known as OX40L and CD134L. The OX40 ligand is expressed on activated B cells and antigen presenting cells. OX40 ligand interacts with OX40 antigen (CD134) expressed predominantly on activated T cells to increase proliferation and IL-2 production, and to enhance proliferation and immunoglobulin secretion in activated B cells. The RM134L antibody can inhibit OX40/OX40 ligand interactions and block the costimulatory activity of OX40L.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol TNFSF4