Reactivity | HuSpecies Glossary |
Applications | WB, ELISA(Cap) |
Clone | 36526 |
Clonality | Monoclonal |
Host | Mouse |
Conjugate | Unconjugated |
Immunogen | S. frugiperda insect ovarian cell line Sf 21-derived recombinant human NT-4 |
Specificity | Detects human NT-4 in direct ELISAs and Western blots. In Western blots, this antibody shows less than 1% cross‑reactivity with recombinant human (rh) NT-3 and rhBDNF. |
Source | N/A |
Isotype | IgG1 |
Clonality | Monoclonal |
Host | Mouse |
Gene | NTF4 |
Purity Statement | Protein A or G purified from hybridoma culture supernatant |
Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
Dilutions |
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Application Notes | ELISA Detection: Human NT-4 Biotinylated Affinity Purified PAb (Catalog number BAF268) Standard: Recombinant Human NT-4 (Catalog number 268-N4) |
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Publications |
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Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
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Buffer | Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS. |
Preservative | No Preservative |
Reconstitution Instructions | Reconstitute at 0.5 mg/mL in sterile PBS. |
NT-4 was originally identified as a mammalian homolog of the Xenopus neurotrophin, NT-4. Along with NGF, BDNF, and NT-3, it is a member of the NGF family of neurotrophic factors that are required for the differentiation and survival of specific neuronal subpopulations in both the central and the peripheral nervous systems. NT-4 functions through interactions with the TrkB receptor tyrosine kinase. Because mammalian NT-4 is much more divergent from its amphibian functional counterpart (Xenopus NT-4) than other family members, it is sometimes designated NT-5 or NT-4/5.
Secondary Antibodies |
Isotype Controls |
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Gene Symbol | NTF4 |