Reactivity | Hu, Mu, RtSpecies Glossary |
Applications | WB, ELISA, ICC/IF, IHC |
Clone | 114C307.1 |
Clonality | Monoclonal |
Host | Mouse |
Conjugate | Biotin |
Immunogen | This Noxa antibody was developed by immunizing mice with a fusion protein containing human Noxa. |
Localization | Mitochondrion, also reported in cytosol (PMID 21145489) and nucleus (PMID 12879012). |
Specificity | An ~80 kDa background band may also be seen in Jurkat cell lysate. |
Isotype | IgG1 Kappa |
Clonality | Monoclonal |
Host | Mouse |
Gene | PMAIP1 |
Purity | Protein G purified |
Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
Dilutions |
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Application Notes | Optimal dilution of this antibody should be experimentally determined. |
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Theoretical MW | 14.96 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
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Readout System | ||
Publications |
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Storage | Store at 4C. Do not freeze. |
Buffer | PBS |
Preservative | 0.05% Sodium Azide |
Purity | Protein G purified |
Secondary Antibodies |
Isotype Controls |
Research Areas for Noxa Antibody (NBP2-24790)Find related products by research area.
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NOXA - a BH3-only protein balancing cell death decisions Noxa is a BH3-only protein involved in regulating cell death decisions. Noxa is a primary p53-response gene and is upregulated in response to p53 overexpression or DNA damage. Noxa can also be induced by alternative mechanisms including through a ... Read full blog post. |
Understanding Noxa Regulation of Apoptosis Noxa is a pro-apoptotic gene belonging to the Bcl2 protein family that is unique in that it contains only BH3 domain. The BH3-only subclass of proteins, including proteins like PUMA and Bim in addition to Noxa, regulate the remaining Bcl-2 family memb... Read full blog post. |
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Gene Symbol | PMAIP1 |