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NCAM-1/CD56 Antibody (1006411) [CoraFluor™ 1]

 
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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, Simple Western, Flow, CyTOF-ready
Clone
1006411
Clonality
Monoclonal
Host
Mouse
Conjugate
CoraFluor 1

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB24084U-100UG
Alexa Fluor 405
FAB24084V-100UG
Alexa Fluor 488
FAB24084G-100UG
Alexa Fluor 532
FAB24084X
Alexa Fluor 594
FAB24084T-100UG
Alexa Fluor 647
FAB24084R-100UG
Alexa Fluor 700
FAB24084N-100UG
Alexa Fluor 750
FAB24084S-100UG
Allophycocyanin
FAB24084A
Allophycocyanin/Cy7
FAB24084APCCY7
Biotin
FAB24084B
DyLight 350
FAB24084D
DyLight 405
FAB24084E
DyLight 488
FAB24084K
DyLight 550
FAB24084L
DyLight 594
FAB24084M
DyLight 650
FAB24084W
DyLight 680
FAB24084Y
DyLight 755
FAB24084Z
FITC
FAB24084F
HRP
FAB24084H
Janelia Fluor 525
FAB24084JF525
Janelia Fluor 549
FAB24084I
Janelia Fluor 585
FAB24084JF585
Janelia Fluor 635
FAB24084JF635
Janelia Fluor 646
FAB24084J
Janelia Fluor 669
FAB24084JF669
PE
FAB24084P
PE/Atto594
FAB24084PEATT594
PE/Cy5.5
FAB24084PECY55
PE/Cy7
FAB24084PECY7
PerCP
FAB24084C
Unconjugated
MAB24084-100
mFluor Violet 450 SE
FAB24084MFV450
mFluor Violet 500 SE
FAB24084MFV500
mFluor Violet 610 SE
FAB24084MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB24084-100
Carrier Free
MAB24084-100
Carrier Free
MAB24084-SP
Carrier Free
FAB24084V-100UG
Carrier Free
FAB24084U-100UG
Carrier Free
FAB24084T-100UG
Carrier Free
FAB24084S-100UG
Carrier Free
FAB24084R-100UG
Carrier Free
FAB24084N-100UG
Carrier Free
FAB24084G-100UG
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NCAM-1/CD56 Antibody (1006411) [CoraFluor™ 1] Summary

Description
CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(IM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.
Immunogen
Mouse myeloma cell line NS0-derived recombinant human NCAM-1/CD56
Leu20-Pro603 and Glu636-Asn741
Accession # NP_001070150
Specificity
Detects human NCAM-1/CD56 in direct ELISAs.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Purity
Protein A or G purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
  • Simple Western
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark. Do not freeze.
Buffer
PBS
Preservative
No Preservative
Purity
Protein A or G purified

Notes

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

Alternate Names for NCAM-1/CD56 Antibody (1006411) [CoraFluor™ 1]

  • CD56 / NCAM-1
  • CD56 antigen
  • CD56
  • MSK39
  • NCAM1
  • N-CAM-1
  • NCAM-1
  • NCAMantigen recognized by monoclonal 5.1H11
  • neural cell adhesion molecule 1
  • neural cell adhesion molecule, NCAM

Background

NCAM, as a member of the immunoglobulin superfamily of adhesion molecules is characterized by several immunoglobulin (Ig) like domains. The extracellular part of NCAM consists of five of these Ig domains and two fibronectin type III homology regions. NCAM is encoded by a single copy gene composed of 26 exons. However, at least 20-30 distinct isoforms can be generated by alternative splicing and by posttranslational modifications, such as sialylation. During sialylation, polysialic acid (PSA) carbohydrates are attached to the extracellular part of NCAM. Through its extracellular region, NCAM mediates homophilic interactions. In addition, NCAM can also undergo heterophilic interactions by binding extracellular matrix components, such as laminin, or other cell adhesion molecules, such as integrins. NCAM is expressed on most neuroectodermal derived cell lines, tissues and neoplasm such as retinoblastoma, medulloblastoma, astrocytomas and neuroblastoma.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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NCAM-1/CD56
Antibody (1006411) [C ...
FAB24084CL1
NCAM-1/CD56 Antibody (1006411) [CoraFluor™ 1]
Species: Hu
Applications: WB, Simple Western, Flow, CyTOF-ready

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