Mouse IL-17F DuoSet ELISA, 15 Plate

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

The IL-17 family is comprised of at least six proinflammatory cytokines that share a conserved cysteine-knot structure but diverge at the N-terminus. IL-17 family members are glycoproteins secreted as dimers that induce local cytokine production and recruit granulocytes to sites of inflammation. IL-17 is induced by IL-15 and IL-23, mainly in activated CD4+ T cells distinct from Th1 or Th2 cells. IL-17F is the most homologous to IL-17, but is induced only by IL-23 in activated monocytes. IL-17B binds the IL-17B receptor, but not the IL-17 receptor; it is most homologous with IL-17D, which is expressed by resting CD4+ T cells and CD19+ B cells. IL-17E is mainly produced by Th2 cells and recruits eosinophils to lung tissue. IL-17C has a very restricted expression pattern but has been detected in adult prostate and fetal kidney libraries.

We have publications tested in 1 confirmed species: Mouse.

Showing Publications 1 - 10 of 13. Show All 13 Publications. Collapse Publications.

Publications using DY2057	Applications	Species
JQ Yang, KW Kalim, Y Li, Y Zheng, F Guo Ablation of RhoA impairs Th17 cell differentiation and alleviates house dust mite-triggered allergic airway inflammation J. Leukoc. Biol., 2019-07-01;0(0):. 2019-07-01 [PMID: 31260596] (Mouse)		Mouse
C Tang, S Kakuta, K Shimizu, M Kadoki, T Kamiya, T Shimazu, S Kubo, S Saijo, H Ishigame, S Nakae, Y Iwakura Suppression of IL-17F, but not of IL-17A, provides protection against colitis by inducing Treg cells through modification of the intestinal microbiota Nat. Immunol., 2018-06-18;0(0):. 2018-06-18 [PMID: 29915298] (Mouse)		Mouse
JS Bowers, MH Nelson, K Majchrzak, SR Bailey, B Rohrer, AD Kaiser, C Atkinson, L Gattinoni, CM Paulos Th17 cells are refractory to senescence and retain robust antitumor activity after long-term ex vivo expansion JCI Insight, 2017-03-09;2(5):e90772. 2017-03-09 [PMID: 28289713] (Mouse)		Mouse
Bernard N, Finlay C, Tannahill G, Cassidy J, O'Neill L, Mills K A critical role for the TLR signaling adapter Mal in alveolar macrophage-mediated protection against Bordetella pertussis. Mucosal Immunol, 2014-12-17;8(5):982-92. 2014-12-17 [PMID: 25515629] (Mouse)		Mouse
Dulek D, Newcomb D, Goleniewska K, Cephus J, Zhou W, Reiss S, Toki S, Ye F, Zaynagetdinov R, Sherrill T, Blackwell T, Moore M, Boyd K, Kolls J, Peebles R Allergic airway inflammation decreases lung bacterial burden following acute Klebsiella pneumoniae infection in a neutrophil- and CCL8-dependent manner. Infect Immun, 2014-06-23;82(9):3723-39. 2014-06-23 [PMID: 24958709] (Mouse)		Mouse
Nedrud J, Bagheri N, Schon K, Xin W, Bergroth H, Eliasson D, Lycke N Subcomponent vaccine based on CTA1-DD adjuvant with incorporated UreB class II peptides stimulates protective Helicobacter pylori immunity. PLoS ONE, 2013-12-31;8(12):e83321. 2013-12-31 [PMID: 24391754] (Mouse)		Mouse
Dubin PJ, Martz A, Eisenstatt JR, Fox MD, Logar A, Kolls JK Interleukin-23-mediated inflammation in Pseudomonas aeruginosa pulmonary infection. Infect. Immun., 2011-10-24;80(1):398-409. 2011-10-24 [PMID: 22025517] (Mouse)		Mouse
Blumberg H, Dinh H, Dean C, Trueblood ES, Bailey K, Shows D, Bhagavathula N, Aslam MN, Varani J, Towne JE, Sims JE IL-1RL2 and its ligands contribute to the cytokine network in psoriasis. J. Immunol., 2010-09-10;185(7):4354-62. 2010-09-10 [PMID: 20833839] (Mouse)		Mouse
Meeks KD, Sieve AN, Kolls JK, Ghilardi N, Berg RE IL-23 is required for protection against systemic infection with Listeria monocytogenes. J. Immunol., 2009-12-15;183(12):8026-34. 2009-12-15 [PMID: 19923464] (Mouse)		Mouse
Nichols JR, Aldrich AL, Mariani MM, Vidlak D, Esen N, Kielian T TLR2 deficiency leads to increased Th17 infiltrates in experimental brain abscesses. J. Immunol., 2009-06-01;182(11):7119-30. 2009-06-01 [PMID: 19454709] (Mouse)		Mouse
Ishigame H, Kakuta S, Nagai T, Kadoki M, Nambu A, Komiyama Y, Fujikado N, Tanahashi Y, Akitsu A, Kotaki H, Sudo K, Nakae S, Sasakawa C, Iwakura Y Differential roles of interleukin-17A and -17F in host defense against mucoepithelial bacterial infection and allergic responses. Immunity, 2009-01-16;30(1):108-19. 2009-01-16 [PMID: 19144317] (Mouse)		Mouse
Rickel EA, Siegel LA, Yoon BR, Rottman JB, Kugler DG, Swart DA, Anders PM, Tocker JE, Comeau MR, Budelsky AL Identification of functional roles for both IL-17RB and IL-17RA in mediating IL-25-induced activities. J. Immunol., 2008-09-15;181(6):4299-310. 2008-09-15 [PMID: 18768888] (Mouse)		Mouse
Wei L, Laurence A, Elias KM, O'Shea JJ IL-21 is produced by Th17 cells and drives IL-17 production in a STAT3-dependent manner. J. Biol. Chem., 2007-09-20;282(48):34605-10. 2007-09-20 [PMID: 17884812] (Mouse)		Mouse
Show All 13 Publications. Collapse Publications.

Array DY2057

• IL-17F Antibodies
• IL-17F ELISA Kit
• IL-17F Lysate
• IL-17F Protein
• IL-17F Proteins and Enzymes
• IL-17F ELISAs