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MMP-10 Antibody (110316)

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC, IP, CyTOF-ready, Flow
Clone
110316
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
IC9102U-100UG
Alexa Fluor 405
IC9102V-100UG
Alexa Fluor 488
IC9102G-100UG
Alexa Fluor 532
FAB9102X
Alexa Fluor 594
IC9102T-100UG
Alexa Fluor 647
IC9102R-100UG
Alexa Fluor 700
IC9102N-100UG
Alexa Fluor 750
IC9102S-100UG
Allophycocyanin
FAB9102A
Biotin
FAB9102B
DyLight 350
FAB9102D
DyLight 405
FAB9102E
DyLight 488
FAB9102K
DyLight 550
FAB9102L
DyLight 594
FAB9102M
DyLight 650
FAB9102W
DyLight 680
FAB9102Y
DyLight 755
FAB9102Z
FITC
FAB9102F
HRP
FAB9102H
Janelia Fluor 525
FAB9102JF525
Janelia Fluor 549
FAB9102I
Janelia Fluor 585
FAB9102JF585
Janelia Fluor 635
FAB9102JF635
Janelia Fluor 646
FAB9102J
Janelia Fluor 669
FAB9102JF669
PE
FAB9102P
PerCP
FAB9102C
View Available Formulations
Catalog# & Formulation Size Price
Carrier Free
MAB9102-SP
Carrier Free
IC9102V-100UG
Carrier Free
IC9102U-100UG
Carrier Free
IC9102T-100UG
Carrier Free
IC9102S-100UG
Carrier Free
IC9102R-100UG
Carrier Free
IC9102N-100UG
Carrier Free
IC9102G-100UG
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MMP-10 Antibody (110316) Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human MMP-10
Phe99-Cys476
Accession # P09238
Specificity
Detects the pro and active forms of human MMP-10 in direct ELISAs Western blots. In direct ELISAs and Western blots, approximately 10‑50% cross‑reactivity with recombinant human (rh) MMP-3 and no cross-reactivity with rhMMP-1, -2, -7, -8, -9, -12, or -13 is observed.
Source
N/A
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
MMP10
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Immunohistochemistry 8-25 ug/mL
  • Immunoprecipitation 25 ug/mL
  • Intracellular Staining by Flow Cytometry 2.5 ug/10^6 cells
  • Western Blot 1 ug/mL
Publications
Read Publication using MAB9102.

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for MMP-10 Antibody (110316)

  • EC 3.4.24
  • EC 3.4.24.22
  • matrix metallopeptidase 10 (stromelysin 2)
  • matrix metalloprotease 10
  • matrix metalloproteinase 10 (stromelysin 2)
  • Matrix metalloproteinase-10
  • MMP10
  • MMP-10
  • SL-2
  • STMY2stromelysin-2
  • Stromelysin 2
  • transin 2
  • transin-2

Background

Matrix metalloproteinases are a family of zinc and calcium dependent endopeptidases with the combined ability to degrade all the components of the extracellular matrix. MMP-10 (stromelysin 2) degrades a broad range of substrates including gelatin, collagen types III, IV and V, fibronectin, aggrecan, and pig cartilage proteoglycan. MMP-10 can activate other MMPs such as MMP-1 and MMP-8. MMP-10 is expressed in keratinocytes, T cells, menstrual endometrium and a few tumor samples. Structurally, MMP-10 may be divided into four distinct domains: a pro-domain which is cleaved upon activation, a catalytic domain containing the zinc binding site; a short linker region, and a carboxyl terminal hemopexin-like domain.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for MMP-10 Antibody (MAB9102)(1)


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Bioinformatics

Gene Symbol MMP10
Uniprot