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MCAM/CD146 Antibody (128018) [Fluorescein]

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HeLa human cervical epithelial carcinoma cell line was stained with Mouse Anti-Human MCAM/CD146 Fluorescein-conjugated Monoclonal Antibody (Catalog # FAB932F, filled histogram) or isotype control antibody (Catalog # ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
128018
Clonality
Monoclonal
Host
Mouse
Conjugate
Fluorescein

Order Details

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MCAM/CD146 Antibody (128018) [Fluorescein] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human MCAM/CD146
Val24-Gly559
Accession # AAA20824
Specificity
Detects human MCAM/CD146 in direct ELISAs and Western blots. In direct ELISAs and Western blots, this antibody does not cross-react with recombinant human (rh) ALCAM, rhBCAM, rhEpCAM, rhNCAM-L1, recombinant mouse (rm)OCAM, or rmMAdCAM-1.
Source
N/A
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
MCAM
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 10 uL/10^6 cells
Publications
Read Publications using
FAB932F in the following applications:

Packaging, Storage & Formulations

Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for MCAM/CD146 Antibody (128018) [Fluorescein]

  • CD146 antigen
  • CD146
  • cell surface glycoprotein MUC18
  • Cell surface glycoprotein P1H12
  • L-Gicerin
  • MCAM
  • melanoma adhesion molecule
  • melanoma cell adhesion moleculeS-endo 1 endothelial-associated antigen
  • Melanoma-associated antigen A32
  • Melanoma-associated antigen MUC18
  • MUC18
  • MUC18Gicerin

Background

MCAM, also known as CD146 and MUC18, is a putative adhesion molecule that belongs to the immunoglobulin superfamily. It is associated with tumor progression and metastasis of various carcinomas and may be involved in embryonic neural development.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for MCAM/CD146 Antibody (FAB932F)(7)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: Flow Cytometry.


Filter By Application
Flow Cytometry
(5)
All Applications
Filter By Species
Human
(5)
All Species
Showing Publications 1 - 7 of 7.
Publications using FAB932F Applications Species
S Mount, P Kanda, S Parent, S Khan, C Michie, L Davila, V Chan, RA Davies, H Haddad, D Courtman, DJ Stewart, DR Davis Physiologic expansion of human heart-derived cells enhances therapeutic repair of injured myocardium Stem Cell Res Ther, 2019-11-04;10(1):316. 2019-11-04 [PMID: 31685023] (Flow Cytometry, Human) Flow Cytometry Human
Mirkina I, Hadzijusufovic E, Krepler C, Mikula M, Mechtcheriakova D, Strommer S, Stella A, Jensen-Jarolim E, Holler C, Wacheck V, Pehamberger H, Valent P Phenotyping of human melanoma cells reveals a unique composition of receptor targets and a subpopulation co-expressing ErbB4, EPO-R and NGF-R. PLoS ONE, 2014-01-29;9(1):e84417. 2014-01-29 [PMID: 24489649]
Qiang Shi, Gerald Schatten, Vida Hodara, Calvin Simerly, John L. VandeBerg Endothelial reconstitution by CD34+ progenitors derived from baboon embryonic stem cells Journal of Cellular and Molecular Medicine 2013-02-01 [PMID: 23301772]
Tura O, Skinner E, Barclay G, Samuel K, Gallagher R, Brittan M, Hadoke P, Newby D, Turner M, Mills N Late outgrowth endothelial cells resemble mature endothelial cells and are not derived from bone marrow. Stem Cells, 2013-02-01;31(2):338-48. 2013-02-01 [PMID: 23165527] (Flow Cytometry, Human) Flow Cytometry Human
Buchheiser A, Houben A, Bosch J, Marbach J, Liedtke S, Kogler G Oxygen tension modifies the 'stemness' of human cord blood-derived stem cells. Cytotherapy, 2012-04-12;14(8):967-82. 2012-04-12 [PMID: 22494073] (Flow Cytometry, Human) Flow Cytometry Human
Liu N, Shi S, Deng M, Tang L, Zhang G, Liu N, Ding B, Liu W, Liu Y, Shi H, Liu L, Jin Y High levels of beta-catenin signaling reduce osteogenic differentiation of stem cells in inflammatory microenvironments through inhibition of the noncanonical Wnt pathway. J. Bone Miner. Res., 2011-09-01;26(9):2082-95. 2011-09-01 [PMID: 21638320] (Flow Cytometry, Human) Flow Cytometry Human
Fujinaga H, Baker CD, Ryan SL, Markham NE, Seedorf GJ, Balasubramaniam V, Abman SH Hyperoxia disrupts vascular endothelial growth factor-nitric oxide signaling and decreases growth of endothelial colony-forming cells from preterm infants. Am. J. Physiol. Lung Cell Mol. Physiol., 2009-09-04;297(6):L1160-9. 2009-09-04 [PMID: 19734318] (Flow Cytometry, Human) Flow Cytometry Human

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Bioinformatics

Gene Symbol MCAM
Uniprot