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Kv7.5 Antibody

Images

 
Immunocytochemistry/ Immunofluorescence: Kv7.5 Antibody [NBP1-82861] - Staining of human cell line U-2 OS shows localization to vesicles. Antibody staining is shown in green.
Orthogonal Strategies: Immunohistochemistry-Paraffin: Kv7.5 Antibody [NBP1-82861] - Staining in human cerebral cortex and pancreas tissues using anti-KCNQ5 antibody. Corresponding KCNQ5 RNA-seq data are presented ...read more
Immunohistochemistry-Paraffin: Kv7.5 Antibody [NBP1-82861] - Staining of human cerebral cortex shows high expression.
Immunohistochemistry-Paraffin: Kv7.5 Antibody [NBP1-82861] - Staining of human pancreas shows low expression as expected.

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Validated by:
       

Orthogonal Strategies

 

Order Details

Kv7.5 Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: LALASFQIPPFECEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSANISRGLQFILTPNEFSAQTFYALSPTMHSQATQVPISQSDGSAVAATNTIANQINTAPKPAAPTTLQIPPPL
Predicted Species
Mouse (91%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
KCNQ5
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 0.25-2 ug/ml
  • Immunohistochemistry 1:20 - 1:50
  • Immunohistochemistry-Paraffin 1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.
Control Peptide
Kv7.5 Protein (NBP1-82861PEP)

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Rat (88%)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for Kv7.5 Antibody

  • KCNQ5
  • KQT-like 5
  • Kv7.5
  • potassium channel protein
  • Potassium channel subunit alpha KvLQT5
  • potassium voltage-gated channel subfamily KQT member 5
  • potassium voltage-gated channel, KQT-like subfamily, member 5
  • Voltage-gated potassium channel subunit Kv7.5

Background

KCNQ5 is a gene that codes for a protein that is thought to be important in the regulation of neuronal excitability, which has 5 isoforms, with lengths of 932, 923, 942, 427, and 822 amino acids and weights of approximately 102, 101, 104, 45, and 90 kDa respectively. Current studies are being done on diseases and disorders related to this gene including pharyngitis, cerebritis, schizophrenia, and neuronitis. KCNQ5 has also been shown to have interactions with CALM1, CALM2, CALM3, DISC1, and KCNQ3 in pathways such as the synaptic transmission-ion currents, dopamine-DARPP32 feedback, potassium channels, and celecoxib pathways.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

FAQs for Kv7.5 Antibody (NBP1-82861) (0)

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol KCNQ5