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IL-17RA/IL-17R Antibody Pair [HRP]

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Sandwich ELISA: IL-17RA/IL-17R Antibody Pair [HRP] [NBP2-79318] - This standard curve is only for demonstration purposes. A standard curve should be generated for each assay.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA
Conjugate
HRP
Standard Curve Range
31.25-2000 pg/ml (example only; lot dependent)
Sensitivity
31.25 pg/ml (example only; lot dependent)

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Catalog# & Conjugate Size Price
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IL-17RA/IL-17R Antibody Pair [HRP] Summary

Description
Solid Phase sandwich ELISA for the quantitative determination of Human IL-17RA/IL-17R.
Specificity
This solid phase sandwich ELISA utilizes a monoclonal antibody specific for Human IL-17RA/IL-17R.
Standard Curve Range
31.25-2000 pg/ml (example only; lot dependent)
Sensitivity
31.25 pg/ml (example only; lot dependent)
Assay Type
Sandwich ELISA
Sample Volume
100 ul
Gene
IL17RA

Applications/Dilutions

Dilutions
  • ELISA
  • Sandwich ELISA

Packaging, Storage & Formulations

Storage
Storage of components varies. See protocol for specific instructions.

Kit Components

Components
  1. Mouse Monoclonal Capture Antibody
  2. Mouse Monoclonal Detection Antibody (HRP-conjugated)
  3. Standard

Alternate Names for IL-17RA/IL-17R Antibody Pair [HRP]

  • CD217 antigen
  • CD217
  • Cdw217
  • CDw217interleukin 17 receptor
  • hIL-17R
  • IL-17 R
  • IL-17 RA
  • IL-17 receptor A
  • IL17RA
  • IL-17RA
  • IL-17RAMGC10262
  • IL17Rinterleukin-17 receptor A
  • interleukin 17 receptor A

Background

IL17RA is a gene that codes for a widely expressed protein that functions as a receptor for IL17A (a proinflammatory cytokine secreted by T-lymphocytes) with low affinity, which suggests that additional components are necessary to induce signaling and has a length of 866 amino acids and a weight of approximately 96 kDa. Current studies are being done on several diseases and disorders related to this gene including rheumatoid arthritis, cat eye syndrome, candidiasis, pituitary adenoma, bronchiolitis, cystic fibrosis, Sjogren's syndrome, keratitis, myocarditis, hepatitis B, liver disease, gingivitis, and osteoarthritis. IL17RA has also been shown to have interactions with IL17F, IL17RE, UBC, and TRAF3IP2 in pathways such as the IL-21 signaling, NF-kappaB signaling, and cytokine production pathways.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are guaranteed for 6 months from date of receipt.

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Bioinformatics

Gene Symbol IL17RA