IL-10 R beta Antibody (009) [PerCP] Summary
Additional Information |
Recombinant Monoclonal Antibody |
Immunogen |
This antibody was obtained from a rabbit immunized with purified, recombinant Mouse IL-10 R beta (Accession#: NP_032375.2; Met1-Ser222). |
Isotype |
IgG |
Clonality |
Monoclonal |
Host |
Rabbit |
Gene |
IL10RB |
Purity |
Protein A purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- ELISA
- Sandwich ELISA Capture
|
Application Notes |
Optimal dilution of this antibody should be experimentally determined. |
Packaging, Storage & Formulations
Storage |
Store at 4C in the dark. |
Buffer |
PBS |
Preservative |
0.05% Sodium Azide |
Purity |
Protein A purified |
Alternate Names for IL-10 R beta Antibody (009) [PerCP]
Background
IL10RB, also known as Interleukin-10 receptor subunit beta, is a 325 amino acid protein that is 37 kDa; belongs to the type II cytokine receptor family; cell surface receptor required for the activation of five class 2 cytokines: IL10, IL22, IL26, IL28, and IL29; and its co-expression with IL10RA proteins is needed for IL10-induced signal transduction. This protein is currently being studied for research on several diseases and disorders including inflammatory bowel disease 25, early onset, autosomal recessive, hepatitis b virus, inflammatory bowel disease, hepatitis b, interferon, respiratory syncytial virus bronchiolitis, graft versus host disease, ulcerative colitis crohn's disease, anaplastic large cell lymphoma, secondary hyperparathyroidism, mumps, systemic lupus erythematosus, measles, bronchiolitis, rubella, cblc, lupus erythematosus, rheumatoid arthritis, colitis, and tumors. Interactions with IL10RB have been shown to involve IL22, UCN3, IL10RA, IL28A, and IL10 in cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, toxoplasmosis, tuberculosis, antioxidant action of vitamin-C, immune response IL-22 signaling pathway, and molecular mechanisms of cancer pathway.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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FAQs for IL-10 R beta Antibody (NBP2-90735PCP) (0)
Secondary Antibodies
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Isotype Controls
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