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IA-2/PTPRN Antibody

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Immunocytochemistry/Immunofluorescence: IA-2/PTPRN Antibody [NBP2-58897] - Staining of human cell line BJ shows localization to endoplasmic reticulum. Antibody staining is shown in green.
Immunocytochemistry/ Immunofluorescence: IA-2/PTPRN Antibody [NBP2-58897] - Staining of human cell line BJ shows localization to endoplasmic reticulum. Antibody staining is shown in green.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

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IA-2/PTPRN Antibody Summary

Immunogen
This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: HSYGDLPGPSPAQLFQDSGLLYLAQELPAPSRARVPRLPEQGSSSRAEDSPEGYEKEGLGDRGEKPASPAVQPDAALQRLAAVLAGYGVELRQLTPEQLSTLLTLLQLLPKGA
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PTPRN
Purity
Affinity purified
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 0.25-2 ug/ml
Application Notes
ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.
Control Peptide
IA-2/PTPRN Recombinant Protein Antigen (NBP2-58897PEP)

Reactivity Notes

Rat 81%

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for IA-2/PTPRN Antibody

  • CA 512
  • EC 3.1.3.48
  • FLJ16131
  • IA2
  • IA-2
  • IA-2/PTP
  • ICA 512
  • ICA3
  • ICA512
  • islet cell antigen 2
  • Islet cell antigen 512
  • Islet cell autoantigen 3
  • protein tyrosine phosphatase, receptor type, N
  • protein tyrosine phosphatase-like N
  • PTP IA-2
  • PTPRN
  • receptor-type tyrosine-protein phosphatase-like N
  • R-PTP-N

Background

PTPRN is encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol PTPRN