Human IL-6 DuoSet ELISA, 15 Plate

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Interleukin 6 (IL-6) is a pleiotropic, a-helical, 22-28 kDa phosphorylated and variably glycosylated cytokine that plays important roles in the acute phase reaction, inflammation, hematopoiesis, bone metabolism, and cancer progression. Mature human IL-6 is 183 amino acids (aa) in length and shares 39% aa sequence identity with mouse and rat IL-6. Alternative splicing generates several isoforms with internal deletions, some of which exhibit antagonistic properties. Cells known to express IL-6 include CD8+ T cells, fibroblasts, synoviocytes, adipocytes, osteoblasts, megakaryocytes, endothelial cells (under the influence of endothelins), sympathetic neurons, cerebral cortex neurons, adrenal medulla chromaffin cells, retinal pigment cells, mast cells, keratinocytes, Langerhans cells, fetal and adult astrocytes, neutrophils, monocytes, eosinophils, colonic epithelial cells, B1 B cells and pancreatic islet beta cells. IL-6 production is generally correlated with cell activation and is normally kept in control by glucocorticoids, catecholamines, and secondary sex steroids. Normal human circulating IL-6 is in the 1 pg/mL range, with slight elevations during the menstrual cycle, modest elevations in certain cancers, and large elevations after surgery.

IL-6 induces signaling through a cell surface heterodimeric receptor complex composed of a ligand binding subunit (IL-6 R alpha) and a signal transducing subunit (gp130). IL-6 binds to IL-6 Ra, triggering IL-6 Ra association with gp130 and gp130 dimerization. gp130 is also a component of the receptors for CLC, CNTF, CT-1, IL-11, IL-27, LIF, and OSM. Soluble forms of IL-6 Ra are generated by both alternative splicing and proteolytic cleavage. In a mechanism known as trans-signaling, complexes of soluble IL-6 and IL-6 Ra elicit responses from gp130-expressing cells that lack cell surface IL-6 Ra. Trans-signaling enables a wider range of cell types to respond to IL-6, as the expression of gp130 is ubiquitous, while that of IL-6 Ra is predominantly restricted to hepatocytes, monocytes, and resting lymphocytes. Soluble splice forms of gp130 block trans-signaling from IL-6/IL-6 Ra but not from other cytokines that use gp130 as a co-receptor. 

IL-6, along with TNF-a and IL-1, drives the acute inflammatory response. IL-6 is almost solely responsible for fever and the acute phase response in the liver, and it is important in the transition from acute inflammation to either acquired immunity or chronic inflammatory disease. When dysregulated, it contributes to chronic inflammation in conditions such as obesity, insulin resistance, inflammatory bowel disease, arthritis, and sepsis. IL-6 modulates bone resorption and is a major effector of inflammatory joint destruction in rheumatoid arthritis through its promotion of Th17 cell development and activity. It contributes to atherosclerotic plaque development and destabilization as well as the development of inflammation-associated carcinogenesis.

We have publications tested in 5 confirmed species: Human, Mouse, Rat, Porcine,  Human.

We have publications tested in 2 applications: ChIP, ELISA Detection.

Showing Publications 1 - 10 of 557. Show All 557 Publications. Collapse Publications.

Publications using DY206	Applications	Species
Louault, K;Blavier, L;Lee, MH;Kennedy, RJ;Fernandez, GE;Pawel, BR;Asgharzadeh, S;DeClerck, YA; Nuclear factor-?B activation by transforming growth factor-?1 drives tumour microenvironment-mediated drug resistance in neuroblastoma British journal of cancer 2024-05-28 [PMID: 38806726] (Human)		Human
Marinho, A;Seabra, CL;Lima, SAC;Lobo-da-Cunha, A;Reis, S;Nunes, C; Empowering Naringin's Anti-Inflammatory Effects through Nanoencapsulation International journal of molecular sciences 2024-04-09 [PMID: 38673736] (Human)		Human
Finegood, ED;Weissman-Tsukamoto, R;Lam, P;Chen, E;Miller, GE; Interpersonal violence exposure and inflammation during adolescence and young adulthood Psychoneuroendocrinology 2024-03-11 [PMID: 38518706] (Human)		Human
Assis, SIS;Amendola, LS;Okamoto, MM;Ferreira, GDS;Iborra, RT;Santos, DR;Santana, MFM;Santana, KG;Correa-Giannella, ML;Barbeiro, DF;Soriano, FG;Machado, UF;Passarelli, M; The Prolonged Activation of the p65 Subunit of the NF-Kappa-B Nuclear Factor Sustains the Persistent Effect of Advanced Glycation End Products on Inflammatory Sensitization in Macrophages International journal of molecular sciences 2024-02-27 [PMID: 38473959] (Human)		Human
Li, Y;Nie, Y;Yang, X;Liu, Y;Deng, X;Hayashi, Y;Plummer, R;Li, Q;Luo, N;Kasai, T;Okumura, T;Kamishibahara, Y;Komoto, T;Ohkuma, T;Okamoto, S;Isobe, Y;Yamaguchi, K;Furukawa, Y;Taniguchi, H; Integration of Kupffer cells into human iPSC-derived liver organoids for modeling liver dysfunction in sepsis Cell reports 2024-03-05 [PMID: 38451817] (Human)		Human
Ray, I;Möller-Levet, CS;Michael, A;Butler-Manuel, S;Chatterjee, J;Tailor, A;Ellis, PE;Meira, LB; Circulating Adipocytokines and Insulin Like-Growth Factors and Their Modulation in Obesity-Associated Endometrial Cancer Cancers 2024-01-26 [PMID: 38339282] (Human)		Human
Vicariotto, F;Malfa, P;Viciani, E;Dell'Atti, F;Squarzanti, DF;Marcante, A;Castagnetti, A;Ponchia, R;Governini, L;De Leo, V; Efficacy of Lactiplantibacillus plantarum PBS067, Bifidobacterium animalis subsp. lactis BL050, and Lacticaseibacillus rhamnosus LRH020 in the Amelioration of Vaginal Microbiota in Post-Menopausal Women: A Prospective Observational Clinical Trial Nutrients 2024-01-30 [PMID: 38337685] (Human)		Human
Zhang, Y;Bharathi, V;Dokoshi, T;de Anda, J;Ursery, LT;Kulkarni, NN;Nakamura, Y;Chen, J;Luo, EWC;Wang, L;Xu, H;Coady, A;Zurich, R;Lee, MW;Matsui, T;Lee, H;Chan, LC;Schepmoes, AA;Lipton, MS;Zhao, R;Adkins, JN;Clair, GC;Thurlow, LR;Schisler, JC;Wolfgang, MC;Hagan, RS;Yeaman, MR;Weiss, TM;Chen, X;Li, MMH;Nizet, V;Antoniak, S;Mackman, N;Gallo, RL;Wong, GCL; Viral afterlife: SARS-CoV-2 as a reservoir of immunomimetic peptides that reassemble into proinflammatory supramolecular complexes Proceedings of the National Academy of Sciences of the United States of America 2024-02-06 [PMID: 38306481] (Human)		Human
Mestriner, F;Francisco, DF;Campos, LCB;Couto, AES;Fraga-Silva, TFC;Flora Dugaich, V;D Avila-Mesquita, C;Zukowski Kovacs, H;Vasconcelos, JL;Milani, ER;Santos Guedes de Sá, K;Martins, R;Jordani, MC;Corsi, CAC;Barbosa, JM;Vasconcelos, T;Gonçalves Menegueti, M;Neto, J;da Costa, RM;Evora, PRB;Arruda, E;Tostes, R;Polonis, K;Bonato, VLD;Auxiliadora-Martins, M;Ribeiro, MS;Becari, C; Alpha 1-acid glycoprotein is upregulated in severe COVID-19 patients and decreases neutrophil NETs in SARS-CoV-2 infection Cytokine 2024-01-31 [PMID: 38301358] (Human)		Human
Bo?kun, ?;Starosz, A;Kr?towska-Grunwald, A;Wasiluk, T;Walewska, A;Wierzbowska, A;Moniuszko, M;Grubczak, K; Effects of Combinatory In Vitro Treatment with Immune Checkpoint Inhibitors and Cytarabine on the Anti-Cancer Immune Microenvironment in De Novo AML Patients Cancers 2024-01-22 [PMID: 38275902] (Human)		Human
Macrì, F;Vigorito, I;Castiglione, S;Faggiano, S;Casaburo, M;Fanotti, N;Piacentini, L;Vigetti, D;Vinci, MC;Raucci, A; High Phosphate-Induced JAK-STAT Signalling Sustains Vascular Smooth Muscle Cell Inflammation and Limits Calcification Biomolecules 2023-12-24 [PMID: 38254629] (Human)		Human
Ozmen, A;Nwabuobi, C;Tang, Z;Guo, X;Larsen, K;Guller, S;Blas, J;Moore, M;Kayisli, UA;Lockwood, CJ;Guzeloglu-Kayisli, O; Leptin-Mediated Induction of IL-6 Expression in Hofbauer Cells Contributes to Preeclampsia Pathogenesis International journal of molecular sciences 2023-12-21 [PMID: 38203306] (Human)		Human
Kuçi, Z;Piede, N;Vogelsang, K;Pfeffermann, LM;Wehner, S;Salzmann-Manrique, E;Stais, M;Kreyenberg, H;Bonig, H;Bader, P;Kuçi, S; Expression of HLA-DR by mesenchymal stromal cells in the platelet lysate era: an obsolete release criterion for MSCs? Journal of translational medicine 2024-01-09 [PMID: 38195462] (Human)		Human
Sullivan, MA;Lane, SD;McKenzie, ADJ;Ball, SR;Sunde, M;Neely, GG;Moreno, CL;Maximova, A;Werry, EL;Kassiou, M; iPSC-derived PSEN2 (N141I) astrocytes and microglia exhibit a primed inflammatory phenotype Journal of neuroinflammation 2024-01-04 [PMID: 38178159] (Human)		Human
Räth, U;Mester, P;Schwarz, H;Schmid, S;Müller, M;Buechler, C;Pavel, V; Soluble CD137: A Potential Prognostic Biomarker in Critically Ill Patients International journal of molecular sciences 2023-12-15 [PMID: 38139346] (Human)		Human
Lee, KS;Kim, Y;Lee, JH;Shon, S;Kim, A;Pham, AVQ;Kim, C;Kim, DH;Kim, YK;Cho, EG; Human Probiotic Lactobacillus paracasei-Derived Extracellular Vesicles Improve Tumor Necrosis Factor-?-Induced Inflammatory Phenotypes in Human Skin Cells 2023-12-07 [PMID: 38132109] (Human)		Human
Wu, WC;Shiu, C;Tong, TK;Leung, SO;Hui, CW; Suppression of NK Cell Activation by JAK3 Inhibition: Implication in the Treatment of Autoimmune Diseases Journal of immunology research 2023-12-08 [PMID: 38106519] (Human)		Human
de Sousa, DC;Sobreira, EST;Feitosa, WLQ;Aires, TMPM;Araújo, LPP;Silva, ALC;Joventino, CB;Silveira, NMT;Chaves-Filho, AJM;Macêdo, DS;Braga-Neto, P; Cognitive dysfunction in systemic lupus erythematosus is associated with disease activity and oxidative stress: a comparative study with rheumatoid arthritis for identifying biomarkers BMC neuroscience 2023-12-13 [PMID: 38093175] (Human)		Human
Sivaraman, K;Pino, P;Raussin, G;Anchisi, S;Metayer, C;Dagany, N;Held, J;Wrenger, S;Welte, T;Wurm, MJ;Wurm, FM;Olejnicka, B;Janciauskiene, S; Human PBMCs Form Lipid Droplets in Response to Spike Proteins Microorganisms 2023-11-01 [PMID: 38004695] (Human)		Human
Cholon, DM;Greenwald, MA;Higgs, MG;Quinney, NL;Boyles, SE;Meinig, SL;Minges, JT;Chaubal, A;Tarran, R;Ribeiro, CMP;Wolfgang, MC;Gentzsch, M; A Novel Co-Culture Model Reveals Enhanced CFTR Rescue in Primary Cystic Fibrosis Airway Epithelial Cultures with Persistent Pseudomonas aeruginosa Infection Cells 2023-11-13 [PMID: 37998353] (Human)		Human
Rother, N;Yanginlar, C;Prévot, G;Jonkman, I;Jacobs, M;van Leent, MMT;van Heck, J;Matzaraki, V;Azzun, A;Morla-Folch, J;Ranzenigo, A;Wang, W;van der Meel, R;Fayad, ZA;Riksen, NP;Hilbrands, LB;Lindeboom, RGH;Martens, JHA;Vermeulen, M;Joosten, LAB;Netea, MG;Mulder, WJM;van der Vlag, J;Teunissen, AJP;Duivenvoorden, R; Acid ceramidase regulates innate immune memory Cell reports 2023-11-22 [PMID: 37995184] (Human)		Human
Kingkaew, E;Woraprayote, W;Booncharoen, A;Niwasabutra, K;Janyaphisan, T;Vilaichone, RK;Yamaoka, Y;Visessanguan, W;Tanasupawat, S; Functional genome analysis and anti-Helicobacter pylori activity of a novel bacteriocinogenic Lactococcus sp. NH2-7C from Thai fermented pork (Nham) Scientific reports 2023-11-21 [PMID: 37990119] (Human)		Human
Sereti, I;Verburgh, ML;Gifford, J;Lo, A;Boyd, A;Verheij, E;Verhoeven, A;Wit, FWNM;Schim van der Loeff, MF;Giera, M;Kootstra, NA;Reiss, P;Vujkovic-Cvijin, I; Impaired gut microbiota-mediated short-chain fatty acid production precedes morbidity and mortality in people with HIV Cell reports 2023-10-30 [PMID: 37918403] (Human)		Human
Gysan, MR;Milacek, C;Bal, C;Zech, A;Brugger, J;Milos, RI;Antoniewicz, L;Idzko, M;Gompelmann, D; Ventilatory support and inflammatory peptides in hospitalised patients with COVID-19: A prospective cohort trial PloS one 2023-11-02 [PMID: 37917760] (Human)		Human
Campesi, I;Capobianco, G;Cano, A;Lodde, V;Cruciani, S;Maioli, M;Sotgiu, G;Idda, ML;Puci, MV;Ruoppolo, M;Costanzo, M;Caterino, M;Cambosu, F;Montella, A;Franconi, F; Stratification of Amniotic Fluid Cells and Amniotic Fluid by Sex Opens Up New Perspectives on Fetal Health Biomedicines 2023-10-18 [PMID: 37893203] (Human)		Human
Ellefsen, CF;Lindstad, L;Klau, LJ;Aachmann, FL;Hiorth, M;Samuelsen, ABC; Investigation of the structural and immunomodulatory properties of alkali-soluble ?-glucans from Pleurotus eryngii fruiting bodies Carbohydrate polymers 2023-12-15 [PMID: 37839837] (Human)		Human
Chung, IC;Huang, WC;Huang, YT;Chen, ML;Tsai, AW;Wu, PY;Yuan, TT; Unrevealed roles of extracellular enolase?1 (ENO1) in promoting glycolysis and pro?cancer activities in multiple myeloma via hypoxia?inducible factor 1? Oncology reports 2023-11-01 [PMID: 37800625] (Human, Mouse)		Human, Mouse
Flores Gomez, D;Bekkering, S;Horst, RT;Cossins, B;van den Munckhof, ICL;Rutten, JHW;Joosten, LAB;Netea, MG;Riksen, NP; The effect of leptin on trained innate immunity and on systemic inflammation in subjects with obesity Journal of leukocyte biology 2023-09-30 [PMID: 37776323] (Human)		Human
Kaneki, M;Ohira, C;Takahashi, M;Iwashita, N;Takagi, Y;Nagane, M;Uchiyama, J;Fukuyama, T; Therapeutic potential of ozone water treatment in alleviating atopic dermatitis symptoms in mouse models: Exploring its bactericidal and direct anti-inflammatory properties International immunopharmacology 2023-09-14 [PMID: 37716162] (Human)		Human
Tran, TT;Phung, TTB;Tran, DM;Bui, HT;Nguyen, PTT;Vu, TT;Ngo, NTP;Nguyen, MT;Nguyen, AH;Nguyen, ATV; Efficient symptomatic treatment and viral load reduction for children with influenza virus infection by nasal-spraying Bacillus spore probiotics Scientific reports 2023-09-08 [PMID: 37684332] (Human)		Human
Burger, K;Jung, F;Baumann, A;Brandt, A;Staltner, R;Sánchez, V;Bergheim, I; TNF? is a key trigger of inflammation in diet-induced non-obese MASLD in mice Redox biology 2023-09-01 [PMID: 37683301] (Human)		Human
Cao, QT;Ishak, M;Shpilman, I;Hirota, JA; TNF-? and Poly(I:C) induction of A20 and activation of NF-?B signaling are independent of ABCF1 in human airway epithelial cells Scientific reports 2023-09-07 [PMID: 37679460] (Human)		Human
Twarog, M;Schustak, J;Xu, Y;Coble, M;Dolan, K;Esterberg, R;Huang, Q;Saint-Geniez, M;Bao, Y; TNF? induced by DNA-sensing in macrophage compromises retinal pigment epithelial (RPE) barrier function Scientific reports 2023-09-02 [PMID: 37660150] (Human)		Human
Montezano, AC;Camargo, LL;Mary, S;Neves, KB;Rios, FJ;Stein, R;Lopes, RA;Beattie, W;Thomson, J;Herder, V;Szemiel, AM;McFarlane, S;Palmarini, M;Touyz, RM; SARS-CoV-2 spike protein induces endothelial inflammation via ACE2 independently of viral replication Scientific reports 2023-08-28 [PMID: 37640791] (Human)		Human
Jeon, S;Jeon, JH;Jeong, J;Kim, G;Lee, S;Kim, S;Maruthupandy, M;Lee, K;Yang, SI;Cho, WS; Size- and oxidative potential-dependent toxicity of environmentally relevant expanded polystyrene styrofoam microplastics to macrophages Journal of hazardous materials 2023-08-14 [PMID: 37597397] (Human)		Human
Faria, J;Ahmed, S;Stamatialis, D;Verhaar, MC;Masereeuw, R;Gerritsen, KGF;Mih?il?, SM; Bioengineered Kidney Tubules Efficiently Clear Uremic Toxins in Experimental Dialysis Conditions International journal of molecular sciences 2023-08-04 [PMID: 37569805] (Human)		Human
Lindquist, S;Wang, Y;Andersson, EL;Tsuji Grebe, S;Alenius, GM;Rantapää-Dahlqvist, S;Lundberg, L;Hernell, O; Effects of bile salt-stimulated lipase on blood cells and associations with disease activity in human inflammatory joint disorders PloS one 2023-08-11 [PMID: 37566600] (Human)		Human
Grubczak, K;Starosz, A;Makowska, B;Parfienowicz, Z;Kr?towska, M;Naumnik, B;Moniuszko, M; The influence of calcitriol and methylprednisolone on podocytes function in minimal change disease in vitro model Scientific reports 2023-08-05 [PMID: 37543700] (Human)		Human
Zhou, L;Fang, L;Tamm, M;Stolz, D;Roth, M; Extracellular Heat Shock Protein 70 Increases the Glucocorticoid Receptor and Dual-Specificity Phosphatase 1 via Toll-like Receptor 4 and Attenuates Inflammation in Airway Epithelial Cells International journal of molecular sciences 2023-07-20 [PMID: 37511459] (Human)		Human
Matsunaga, T;Sano, H;Takita, K;Morita, M;Yamanaka, S;Ichikawa, T;Numakura, T;Ida, T;Jung, M;Ogata, S;Yoon, S;Fujino, N;Kyogoku, Y;Sasaki, Y;Koarai, A;Tamada, T;Toyama, A;Nakabayashi, T;Kageyama, L;Kyuwa, S;Inaba, K;Watanabe, S;Nagy, P;Sawa, T;Oshiumi, H;Ichinose, M;Yamada, M;Sugiura, H;Wei, FY;Motohashi, H;Akaike, T; Supersulphides provide airway protection in viral and chronic lung diseases Nature communications 2023-07-25 [PMID: 37491435] (Human)		Human
Malaga, W;Payros, D;Meunier, E;Frigui, W;Sayes, F;Pawlik, A;Orgeur, M;Berrone, C;Moreau, F;Mazères, S;Gonzalo-Asensio, J;Rengel, D;Martin, C;Astarie-Dequeker, C;Mourey, L;Brosch, R;Guilhot, C; Natural mutations in the sensor kinase of the PhoPR two-component regulatory system modulate virulence of ancestor-like tuberculosis bacilli PLoS pathogens 2023-07-01 [PMID: 37450466] (Human)		Human
Isanejad, A;Nazari, S;Gharib, B;Motlagh, AG; Comparison of the effects of high-intensity interval and moderate-intensity continuous training on inflammatory markers, cardiorespiratory fitness, and quality of life in breast cancer patients Journal of sport and health science 2023-07-07 [PMID: 37423313] (Human)		Human
Kalsi, KK;Jackson, S;Baines, DL; Lipoxin receptor agonist and inhibition of LTA4 hydrolase prevent tight junction disruption caused by P. aeruginosa filtrate in airway epithelial cells PloS one 2023-07-05 [PMID: 37406028] ( Human)		Human
Vieira, SF;Araújo, J;Gonçalves, VMF;Fernandes, C;Pinto, M;Ferreira, H;Neves, NM;Tiritan, ME; Synthesis and Anti-Inflammatory Evaluation of a Library of Chiral Derivatives of Xanthones Conjugated with Proteinogenic Amino Acids International journal of molecular sciences 2023-06-19 [PMID: 37373503] (Human)		Human
Kirsten, N;Ohmes, J;Mikkelsen, MD;Nguyen, TT;Blümel, M;Wang, F;Tasdemir, D;Seekamp, A;Meyer, AS;Fuchs, S; Impact of Enzymatically Extracted High Molecular Weight Fucoidan on Lipopolysaccharide-Induced Endothelial Activation and Leukocyte Adhesion Marine drugs 2023-05-31 [PMID: 37367664] (Human)		Human
Ferreira, AV;Kostidis, S;Groh, LA;Koeken, VACM;Bruno, M;Baydemir, I;Kilic, G;Bulut, Ö;Andriopoulou, T;Spanou, V;Synodinou, KD;Gkavogianni, T;Moorlag, SJCFM;Charlotte de Bree, L;Mourits, VP;Matzaraki, V;Koopman, WJH;van de Veerdonk, FL;Renieris, G;Giera, M;Giamarellos-Bourboulis, EJ;Novakovic, B;Domínguez-Andrés, J; Dimethyl itaconate induces long-term innate immune responses and confers protection against infection Cell reports 2023-06-16 [PMID: 37330914] ( Human)		Human
Warren, KJ;Beck, EM;Callahan, SJ;Helms, MN;Middleton, E;Maddock, S;Carr, JR;Harris, D;Blagev, DP;Lanspa, MJ;Brown, SM;Paine, R; Alveolar macrophages from EVALI patients and e-cigarette users: a story of shifting phenotype Respiratory research 2023-06-17 [PMID: 37330506] (Human)		Human
Langgartner, D;Winkler, R;Brunner-Weisser, J;Rohleder, N;Jarczok, MN;Gündel, H;Weimer, K;Reber, SO; COVID-19 vaccination exacerbates ex vivo IL-6 release from isolated PBMCs Scientific reports 2023-06-12 [PMID: 37308487] (Human)		Human
Chang, JP;Chang, SS;Chen, HT;Chien, YC;Yang, HT;Huang, SY;Tseng, PT;Chang, CH;Galecki, P;Su, KP; Omega-3 polyunsaturated fatty acids (n-3 PUFAs), somatic and fatigue symptoms in cardiovascular diseases comorbid major depressive disorder (MDD): A randomized controlled trial Brain, behavior, and immunity 2023-06-09 [PMID: 37301235] (Human)		Human
Toffoli, B;Tonon, F;Giudici, F;Ferretti, T;Ghirigato, E;Contessa, M;Francica, M;Candido, R;Puato, M;Grillo, A;Fabris, B;Bernardi, S; Preliminary Study on the Effect of a Night Shift on Blood Pressure and Clock Gene Expression International journal of molecular sciences 2023-05-26 [PMID: 37298261] (Human)		Human
Gjörloff Wingren, A;Ziyad Faik, R;Holefors, A;Filecovic, E;Gustafsson, A; In vitro effects of undifferentiated callus extracts from Plantago major L, Rhodiola rosea L and Silybum marianum L in normal and malignant human skin cells Heliyon 2023-06-01 [PMID: 37292297] (Human)		Human
Meade, RD;Notley, SR;Akerman, AP;McCormick, JJ;King, KE;Sigal, RJ;Kenny, GP; Efficacy of Cooling Centers for Mitigating Physiological Strain in Older Adults during Daylong Heat Exposure: A Laboratory-Based Heat Wave Simulation Environmental health perspectives 2023-06-01 [PMID: 37262028] (Human)		Human
Li, C;Ture, SK;Nieves-Lopez, B;Blick-Nitko, SK;Maurya, P;Livada, AC;Stahl, TJ;Kim, M;Pietropaoli, AP;Morrell, CN; Thrombocytopenia Independently Leads to Monocyte Immune Dysfunction bioRxiv : the preprint server for biology 2023-05-12 [PMID: 37214993] (Human)		Human
Jeon, KB;Kim, J;Lim, CM;Park, JY;Kim, NY;Lee, J;Oh, DK;Yoon, DY; Unsaturated oxidated fatty acid 12(S)-HETE attenuates TNF-? expression in TNF-?/IFN-?-stimulated human keratinocytes International immunopharmacology 2023-05-17 [PMID: 37207444] (Human)		Human
Montero, P;Roger, I;Estornut, C;Milara, J;Cortijo, J; Influence of dose and exposition time in the effectiveness of N-Acetyl-l-cysteine treatment in A549 human epithelial cells Heliyon 2023-05-01 [PMID: 37144195] (Human)		Human
A Chovsepian, O Prokopchuk, G Petrova, T Gjini, H Kuzi, S Heisz, KP Janssen, ME Martignoni, H Friess, H Hauner, M Rohm Diabetes increases mortality in patients with pancreatic and colorectal cancer by promoting cachexia and its associated inflammatory status Molecular Metabolism, 2023-04-22;0(0):101729. 2023-04-22 [PMID: 37094629] (Human)		Human
P Banerjee, AR Mehta, RS Nirujogi, J Cooper, OG James, J Nanda, J Longden, K Burr, K McDade, A Salzinger, E Paza, J Newton, D Story, S Pal, C Smith, DR Alessi, BT Selvaraj, J Priller, S Chandran Cell-autonomous immune dysfunction driven by disrupted autophagy in C9orf72-ALS iPSC-derived microglia contributes to neurodegeneration Science Advances, 2023-04-21;9(16):eabq0651. 2023-04-21 [PMID: 37083530] (Human)		Human
YH Chen, D Nguyen, S Brindley, T Ma, T Xia, J Brune, JM Brown, CS Tsai The dependence of particle size on cell toxicity for modern mining dust Scientific Reports, 2023-03-29;13(1):5101. 2023-03-29 [PMID: 36991007] (Human)		Human
Y Guo, V Kanamarlap Molecular Analysis of SARS-CoV-2 Spike Protein-Induced Endothelial Cell Permeability and vWF Secretion International Journal of Molecular Sciences, 2023-03-16;24(6):. 2023-03-16 [PMID: 36982738] (Human)		Human
S Speaks, A Zani, A Solstad, A Kenney, L Zhang, AC Eddy, AO Amer, R Robinson, C Cai, J Ma, EA Hemann, A Forero, JS Yount Loss of Gasdermin D is protective against influenza virus-induced inflammation and mortality bioRxiv : the preprint server for biology, 2023-04-07;0(0):. 2023-04-07 [PMID: 36945485] (Human)		Human
M Liu, AN Panagopoul, UM Oguz, S Samant, CH Vasa, DK Agrawal, YS Chatzizisi Role of triggering receptor expressed on myeloid cells-1 in the mechanotransduction signaling pathways that link low shear stress with inflammation Scientific Reports, 2023-03-21;13(1):4656. 2023-03-21 [PMID: 36944850] (Human)		Human
A Jurj, O Zanoaga, L Raduly, V Morhan, Z Papi, C Ciocan, LA Pop, I Berindan-N, C Braicu Discovering the Biological Significance and Therapeutic Potential of miR-29b-3p in Triple-Negative Breast Cancer International Journal of Molecular Sciences, 2023-03-06;24(5):. 2023-03-06 [PMID: 36902482] (Human)		Human
R Danielsson, N Ferey, I Mile, H Eriksson Metabolic Reprogramming of Macrophages upon In Vitro Incubation with Aluminum-Based Adjuvant International Journal of Molecular Sciences, 2023-02-23;24(5):. 2023-02-23 [PMID: 36901849] (Human)		Human
V Klück, G Cab?u, L Mies, F Bukkems, L van Emst, R Bakker, A van Caam, HINT conso, TO Cri?an, LAB Joosten TGF-beta is elevated in hyperuricemic individuals and mediates urate-induced hyperinflammatory phenotype in human mononuclear cells Arthritis Research & Therapy, 2023-02-27;25(1):30. 2023-02-27 [PMID: 36850003] (Human)		Human
M Shafiq, ZR Lone, AO Abdulkaree, G Kaur, S Navya, H Singh, K Jagavelu, K Hanif Inhibition of poly (ADP-ribose) Polymerase-1 (PARP-1) improves endothelial function in pulmonary hypertension Pulmonary pharmacology & therapeutics, 2023-02-25;0(0):102200. 2023-02-25 [PMID: 36842770] (Human)		Human
R Nicu, DE Ciolacu, AR Petrovici, D Rusu, M Avadanei, AC Mihaila, E Butoi, F Ciolacu 3D Matrices for Enhanced Encapsulation and Controlled Release of Anti-Inflammatory Bioactive Compounds in Wound Healing International Journal of Molecular Sciences, 2023-02-20;24(4):. 2023-02-20 [PMID: 36835619] (Human)		Human
KB Neves, R Alves-Lope, AC Montezano, RM Touyz Role of PARP and TRPM2 in VEGF Inhibitor-Induced Vascular Dysfunction Journal of the American Heart Association, 2023-02-20;0(0):e027769. 2023-02-20 [PMID: 36802924] (Human)		Human
AJ Heires, D Samuelson, D Villageliu, TM Nordgren, DJ Romberger Agricultural dust derived bacterial extracellular vesicle mediated inflammation is attenuated by DHA Scientific Reports, 2023-02-16;13(1):2767. 2023-02-16 [PMID: 36797300] (Human)		Human
LU Teufel, MG Netea, FL van de Vee, CA Dinarello, LAB Joosten, RJW Arts Opposing Effects of Interleukin-36gamma and Interleukin-38 on Trained Immunity International Journal of Molecular Sciences, 2023-01-24;24(3):. 2023-01-24 [PMID: 36768634] (Human)		Human
RL Schmitz, KE Tweed, P Rehani, K Samimi, J Riendeau, I Jones, EM Maly, EC Guzman, MH Forsberg, A Shahi, CM Capitini, AJ Walsh, MC Skala Autofluorescence lifetime imaging classifies human lymphocyte activation and subtype bioRxiv : the preprint server for biology, 2023-01-23;0(0):. 2023-01-23 [PMID: 36747690] (Human)		Human
M Nicolas, M Lasalo, S Chow, C Antheaume, K Huet, E Hnawia, GJ Guillemin, M Nour, M Matsui Anti-inflammatory activities of Coleus forsteri (formerly Plectranthus forsteri) extracts on human macrophages and chemical characterization Frontiers in Pharmacology, 2023-01-09;13(0):1081310. 2023-01-09 [PMID: 36699063] (Human)		Human
G Bredeck, M Busch, A Rossi, B Stahlmecke, KW Fomba, H Herrmann, RPF Schins Inhalable Saharan dust induces oxidative stress, NLRP3 inflammasome activation, and inflammatory cytokine release Environment international, 2023-01-11;172(0):107732. 2023-01-11 [PMID: 36680803] (Human)		Human
A Dinarello, TS Mills, IW Tengesdal, NE Powers, T Azam, CA Dinarello Dexamethasone and OLT1177 Cooperate in the Reduction of Melanoma Growth by Inhibiting STAT3 Functions Cells, 2023-01-12;12(2):. 2023-01-12 [PMID: 36672229] (Human)		Human
M Liu, S Samant, CH Vasa, RM Pedrigi, UM Oguz, S Ryu, T Wei, DR Anderson, DK Agrawal, YS Chatzizisi Co-culture models of endothelial cells, macrophages, and vascular smooth muscle cells for the study of the natural history of atherosclerosis PLoS ONE, 2023-01-20;18(1):e0280385. 2023-01-20 [PMID: 36662769] (Human)		Human
TTT Nguyen, YH Choi, WK Lee, Y Ji, E Chun, YH Kim, JE Lee, HS Jung, JH Suh, S Kim, M Jin Tryptophan-dependent and -independent secretions of tryptophanyl- tRNA synthetase mediate innate inflammatory responses Cell Reports, 2022-12-30;42(1):111905. 2022-12-30 [PMID: 36640342] (Human)		Human
N Lagneau, P Tournier, B Halgand, F Loll, Y Maugars, J Guicheux, C Le Visage, V Delplace Click and bioorthogonal hyaluronic acid hydrogels as an ultra-tunable platform for the investigation of cell-material interactions Bioactive materials, 2023-01-03;24(0):438-449. 2023-01-03 [PMID: 36632500] (Human)		Human
J Siewiera, K Brodaczews, N Jermakow, A Lubas, K K?os, A Majewska, J Kot Effectiveness of Hyperbaric Oxygen Therapy in SARS-CoV-2 Pneumonia: The Primary Results of a Randomised Clinical Trial Journal of Clinical Medicine, 2022-12-20;12(1):. 2022-12-20 [PMID: 36614808] (Human)		Human
K Shabir, S Gharanei, S Orton, V Patel, P Chauhan, E Karteris, HS Randeva, JE Brown, I Kyrou Asprosin Exerts Pro-Inflammatory Effects in THP-1 Macrophages Mediated via the Toll-like Receptor 4 (TLR4) Pathway International Journal of Molecular Sciences, 2022-12-23;24(1):. 2022-12-23 [PMID: 36613673] (Human)		Human
K Wadowska, P B?asiak, A Rzechonek, I Bil-Lula, M ?liwi?ska- Hepcidin as a Diagnostic Biomarker in Anaemic Lung Cancer Patients Cancers, 2022-12-30;15(1):. 2022-12-30 [PMID: 36612220] (Human)		Human
Q Huang, M Peng, Y Gu, J Wu, Y Zhan, Z Deng, S Chen, R Yang, J Chen, J Xie Metabolism-Related Gene TXNRD1 Regulates Inflammation and Oxidative Stress Induced by Cigarette Smoke through the Nrf2/HO-1 Pathway in the Small Airway Epithelium Oxidative Medicine and Cellular Longevity, 2022-12-19;2022(0):7067623. 2022-12-19 [PMID: 36578523] (Human)		Human
GA Bonaterra, J Schmitt, K Schneider, H Schwarzbac, H Aziz-Kalbh, O Kelber, J Müller, R Kinscherf Phytohustil� and root extract of Althaea officinalis L. exert anti-inflammatory and anti-oxidative properties and improve the migratory capacity of endothelial cells in vitro Frontiers in Pharmacology, 2022-12-08;13(0):948248. 2022-12-08 [PMID: 36569306] (Human)		Human
AO Larsson, M Hultström, R Frithiof, M Lipcsey, MB Eriksson Shrunken Pore Syndrome Is Frequently Occurring in Severe COVID-19 International Journal of Molecular Sciences, 2022-12-10;23(24):. 2022-12-10 [PMID: 36555328] (Human)		Human
Y Hosokawa, I Hosokawa, M Shimoyama, A Fujii, J Sato, K Kadena, K Ozaki, K Hosaka The Anti-Inflammatory Effects of Iberin on TNF-alpha-Stimulated Human Oral Epithelial Cells: In Vitro Research Biomedicines, 2022-12-06;10(12):. 2022-12-06 [PMID: 36551911] (Human)		Human
F Cognasse, H Hamzeh-Cog, M Rosa, D Corseaux, B Bonneaudea, C Pierre, J Huet, CA Arthaud, MA Eyraud, A Prier, AC Duchez, T Ebermeyer, M Heesterman, E Audoux-Cai, Q Philippot, T Le Voyer, O Hequet, AM Fillet, P Chavarin, D Legrand, P Richard, F Pirenne, P Gallian, JL Casanova, S Susen, P Morel, K Lacombe, P Bastard, P Tiberghien Inflammatory markers and auto-Abs to type I IFNs in COVID-19 convalescent plasma cohort study EBioMedicine, 2022-12-17;87(0):104414. 2022-12-17 [PMID: 36535107] (Human)		Human
LAC Teixeira, JM Dos Santos, AN Parentoni, LP Lima, TC Duarte, FP Brant, CDC Neves, FSM Pereira, NCP Avelar, AL Danielewic, AAO Leopoldino, SP Costa, AN Arrieiro, LA Soares, ACN Prates, JNP Nobre, A de Carvalh, VC de Oliveir, MX Oliveira, PH Scheidt Fi, HS Costa, V Amaral Men, R Taiar, AC Rodrigues Adiponectin Is a Contributing Factor of Low Appendicular Lean Mass in Older Community-Dwelling Women: A Cross-Sectional Study Journal of Clinical Medicine, 2022-12-02;11(23):. 2022-12-02 [PMID: 36498747] (Human)		Human
M Fassler, C Benaim, J George A Single Chain Fragment Variant Binding Misfolded Alpha-Synuclein Exhibits Neuroprotective and Antigen-Specific Anti-Inflammatory Properties Cells, 2022-11-29;11(23):. 2022-11-29 [PMID: 36497081] (Human)		Human
LU Teufel, CI van der Ma, V Klück, A Simons, A Hoischen, V Vernimmen, LAB Joosten, RJW Arts Effect of exogenous IL-37 on immune cells from a patient carrying a potential IL37 loss-of-function variant: A case study Cytokine, 2022-12-05;162(0):156102. 2022-12-05 [PMID: 36476991] (Human)		Human
T Luong, E Cukierman Eribulin normalizes pancreatic cancer-associated fibroblasts by simulating selected features of TGFbeta inhibition BMC Cancer, 2022-12-02;22(1):1255. 2022-12-02 [PMID: 36461015] (Human)		Human
VC Capetini, BJ Quintanilh, DC de Oliveir, AH Nishioka, LA de Matos, LRP Ferreira, FM Ferreira, GR Sampaio, NMA Hassimotto, FM Lajolo, RA Fock, MM Rogero Blood orange juice intake modulates plasma and PBMC microRNA expression in overweight and insulin resistance women: impact on MAPK and NFkappaB signaling pathways The Journal of nutritional biochemistry, 2022-11-26;0(0):109240. 2022-11-26 [PMID: 36442716] (Human)		Human
JS Park, SC Yang, HY Jeong, SY Lee, JG Ryu, JW Choi, HY Kang, SM Kim, SH Hwang, ML Cho, SH Park EC-18 prevents autoimmune arthritis by suppressing inflammatory cytokines and osteoclastogenesis Arthritis Research & Therapy, 2022-11-17;24(1):254. 2022-11-17 [PMID: 36397156] (Human)		Human
MJ Barnes, D Lomiwes, DAD Parry, S Mackintosh An experimental model of contusion injury in humans PLoS ONE, 2022-11-17;17(11):e0277765. 2022-11-17 [PMID: 36395119] (Human)		Human
CS Rigazio, N Mariz-Pont, EP Caballero, FN Penas, NB Goren, MH Santamaría, RS Corral Involvement of glycoinositolphospholipid from Trypanosoma cruzi and macrophage migration inhibitory factor in proinflammatory mechanisms promoting cardiovascular injury mechanisms promoting cardiovascular inflammation tThe combined action of glycoinositolphospholipid from Trypanosoma cruzi and macrophage migration inhibitory factor increases proinflammatory mediator production by cardiomyocytes and vascular endothelial cells Microbial pathogenesis, 2022-11-12;0(0):105881. 2022-11-12 [PMID: 36379373] (Human)		Human
SF Vieira, VMF Gonçalves, CP Llaguno, F Macías, ME Tiritan, RL Reis, H Ferreira, NM Neves On the Bioactivity of Echinacea purpurea Extracts to Modulate the Production of Inflammatory Mediators Oncogene, 2022-11-06;23(21):. 2022-11-06 [PMID: 36362404] (Human)		Human
B Saravi, Z Li, V Basoli, S Grad, S Häckel, CE Albers, M Alini, H Schmal, P Obid, G Lang In Vitro Characterization of a Tissue Renin-Angiotensin System in Human Nucleus Pulposus Cells Cells, 2022-10-28;11(21):. 2022-10-28 [PMID: 36359814] (Human)		Human
J Park, D Kim, M Lee, S Han, W Jun, HM Jung, YK Koo, GH Na, SH Han, J Han, OK Kim Enzyme-Treated Caviar Prevents UVB Irradiation-Induced Skin Photoaging Oncogene, 2022-10-30;20(11):. 2022-10-30 [PMID: 36355008] (Human)		Human
L Butcher, JC Zaldua, JA Carnicero, K Hawkins, J Whitley, R Mothukuri, PA Evans, K Morris, S Pillai, JD Erusalimsk High levels of soluble RAGE are associated with a greater risk of mortality in COVID-19 patients treated with dexamethasone Respiratory Research, 2022-11-05;23(1):303. 2022-11-05 [PMID: 36335329] (Human)		Human
G Mariananto, G Meogrossi, E Tollapi, A Rencinai, J Brunetti, C Marruganti, C Gaeta, A Pini, L Bracci, M Ferrari, S Grandini, C Falciani Antimicrobial Peptides Active in In Vitro Models of Endodontic Bacterial Infections Modulate Inflammation in Human Cardiac Fibroblasts Pharmaceutics, 2022-09-29;14(10):. 2022-09-29 [PMID: 36297519] (Human)		Human
W Dieterich, C Schuster, P Gundel, KA Scherf, D Pronin, S Geisslitz, A Börner, MF Neurath, Y Zopf Proteins from Modern and Ancient Wheat Cultivars: Impact on Immune Cells of Healthy Individuals and Patients with NCGS Nutrients, 2022-10-12;14(20):. 2022-10-12 [PMID: 36296938] (Human)		Human
H Wang, Y Li, Z Yue, Y Liu, Q Chen, D Hu, J Han Adipose-Derived Stem Cell Exosomes Inhibit Hypertrophic Scaring Formation by Regulating Th17/Treg Cell Balance BioMed Research International, 2022-10-12;2022(0):9899135. 2022-10-12 [PMID: 36277890] (Human)		Human
M Patankar, M Li, A Khalatbari, JD Castle, L Hu, C Zhang, A Shaker Inflammatory and Proliferative Pathway Activation in Human Esophageal Myofibroblasts Treated with Acidic Bile Salts International Journal of Molecular Sciences, 2022-09-08;23(18):. 2022-09-08 [PMID: 36142285] (Human)		Human
R Lei, H Arain, M Obaid, N Sabhnani, C Mohan Ultra-Sensitive and Semi-Quantitative Vertical Flow Assay for the Rapid Detection of Interleukin-6 in Inflammatory Diseases Biosensors, 2022-09-14;12(9):. 2022-09-14 [PMID: 36140141] (Human)		Human
V Dani, S Bruni-Favi, B Chignon-Si, A Loubat, A Doglio, C Dani Regulation of Adipose Progenitor Cell Expansion in a Novel Micro-Physiological Model of Human Adipose Tissue Mimicking Fibrotic and Pro-Inflammatory Microenvironments Cells, 2022-09-07;11(18):. 2022-09-07 [PMID: 36139371] (Human)		Human
P Marona, J Górka, O Kwapisz, J Jura, J Rys, RM Hoffman, K Miekus Resistance to tyrosine kinase inhibitors promotes renal cancer progression through MCPIP1 tumor-suppressor downregulation and c-Met activation Cell Death & Disease, 2022-09-22;13(9):814. 2022-09-22 [PMID: 36138026] (Human, Mouse)		Human, Mouse
Kartasheva-Ebertz D, Gaston J, Lair-Mehiri L, Mottez E, Buivan T, Massault P, Scatton O, Gaujoux S, Vaillant J, Pol S, Lagaye S IL-17A in Human Liver: Significant Source of Inflammation and Trigger of Liver Fibrosis Initiation. Int J Mol Sci, 2022-08-29;23(17):. 2022-08-29 [PMID: 36077175] (Human)		Human
E The, DM de Graaf, Y Zhai, Q Yao, L Ao, DA Fullerton, CA Dinarello, X Meng Interleukin 38 alleviates aortic valve calcification by inhibition of NLRP3 Proceedings of the National Academy of Sciences of the United States of America, 2022-08-29;119(36):e2202577119. 2022-08-29 [PMID: 36037361] (Human)		Human
M Shafiq, ZR Lone, P Bharati, S Mahapatra, P Rai, N Khandelwal, AN Gaikwad, K Jagavelu, K Hanif Pyrroloquinoline quinone (PQQ) improves pulmonary hypertension by regulating mitochondrial and metabolic functions Pulmonary pharmacology & therapeutics, 2022-08-25;76(0):102156. 2022-08-25 [PMID: 36030026] (Rat)		Rat
L Bolkun, M Tynecka, T Wasiluk, J Piszcz, A Starosz, K Grubczak, M Moniuszko, A Eljaszewic A Proliferation-Inducing Ligand and B-Cell Activating Factor Are Upregulated in Patients with Essential Thrombocythemia Journal of Clinical Medicine, 2022-08-09;11(16):. 2022-08-09 [PMID: 36012902] (Human)		Human
L Sansone, A de Iure, M Cristina, M Belli, L Vitiello, F Marcolongo, A Rosellini, L Macera, PG Spezia, C Tomino, S Bonassi, MA Russo, F Maggi, P Russo Nicotine in Combination with SARS-CoV-2 Affects Cells Viability, Inflammatory Response and Ultrastructural Integrity International Journal of Molecular Sciences, 2022-08-22;23(16):. 2022-08-22 [PMID: 36012747] (Human)		Human
C Amormino, V Tedeschi, G Paldino, S Arcieri, MT Fiorillo, A Paiardini, L Tuosto, M Kunkl SARS-CoV-2 Spike Does Not Possess Intrinsic Superantigen-like Inflammatory Activity Cells, 2022-08-15;11(16):. 2022-08-15 [PMID: 36010602] (Human)		Human
S Manandhar, A Scott-Thom, M Harrington, P Sinha, A Pilbrow, AM Richards, V Cameron, M Bhatia, ST Chambers Hydrogen Sulfide and Substance P Levels in Patients with Escherichia coli and Klebsiella pneumoniae Bacteraemia International Journal of Molecular Sciences, 2022-08-03;23(15):. 2022-08-03 [PMID: 35955767] (Human)		Human
JK Pfromm, M Bonillo, D Dauletbeko, K Bucher, MD Fischer Plasmid-mediated gene transfer of Cas9 induces vector-related but not SpCas9-related immune responses in human retinal pigment epithelial cells Scientific Reports, 2022-08-01;12(1):13202. 2022-08-01 [PMID: 35915300] (Human)		Human
Y Xu, M Twarog, N Li, A Banks, J Schustak, Y Bao, Q Huang, QG Medley Zinc transport from the endoplasmic reticulum to the cytoplasm via Zip7 is necessary for barrier dysfunction mediated by inflammatory signaling in RPE cells PLoS ONE, 2022-07-28;17(7):e0271656. 2022-07-28 [PMID: 35901031] (Human)		Human
OA Chaves, N Fintelman-, X Wang, CQ Sacramento, JR Temerozo, AC Ferreira, M Mattos, F Pereira-Du, PT Bozza, HC Castro-Far, JJ Russo, J Ju, TML Souza Commercially Available Flavonols Are Better SARS-CoV-2 Inhibitors than Isoflavone and Flavones Viruses, 2022-06-30;14(7):. 2022-06-30 [PMID: 35891437] (Human)		Human
M Anselmi, F Fontana, M Marzagalli, N Gagliano, M Sommariva, P Limonta Melanoma Stem Cells Educate Neutrophils to Support Cancer Progression Cancers, 2022-07-13;14(14):. 2022-07-13 [PMID: 35884452] (Human)		Human
S Rutecki, P Szulc, M Paku?a, P Uruski, A Radziemski, E Naumowicz, R Moszy?ski, A Tykarski, J Miku?a-Pie, K Ksi??ek Pro-cancerogenic effects of spontaneous and drug-induced senescence of ovarian cancer cells in vitro and in vivo: a comparative analysis Journal of ovarian research, 2022-07-26;15(1):87. 2022-07-26 [PMID: 35883110] (Human)		Human
J Hu, Y Zhang, S Yi, C Wang, X Huang, S Pan, J Yang, G Yuan, S Tan, H Li Lithocholic acid inhibits dendritic cell activation by reducing intracellular glutathione via TGR5 signaling International journal of biological sciences, 2022-07-11;18(11):4545-4559. 2022-07-11 [PMID: 35864954] (Human)		Human
LAJ Feather, V Nadella, E Kastner, Y Perrie, AC Hilton, A Devitt Development of a rapid in vitro pre-screen for distinguishing effective liposome-adjuvant delivery systems Scientific Reports, 2022-07-20;12(1):12448. 2022-07-20 [PMID: 35859154] (Human)		Human
DM Tran, TT Tran, TTB Phung, HT Bui, PTT Nguyen, TT Vu, NTP Ngo, MT Nguyen, AH Nguyen, ATV Nguyen Nasal-spraying Bacillus spores as an effective symptomatic treatment for children with acute respiratory syncytial virus infection Scientific Reports, 2022-07-20;12(1):12402. 2022-07-20 [PMID: 35858943] (Human)		Human
H Stölting, L Baillon, R Frise, K Bonner, RJ Hewitt, PL Molyneaux, ML Gore, Breathing, WS Barclay, S Saglani, CM Lloyd Distinct airway epithelial immune responses after infection with SARS-CoV-2 compared to H1N1 Mucosal Immunology, 2022-07-15;0(0):. 2022-07-15 [PMID: 35840680] (Human)		Human
RA Wagdy, PJ Chen, MM Hamed, SS Darwish, SH Chen, AH Abadi, M Abdel-Hali, TL Hwang, M Engel From EGFR kinase inhibitors to anti-inflammatory drugs: Optimization and biological evaluation of (4-(phenylamino)quinazolinyl)-phenylthiourea derivatives as novel NF-kappaB inhibitors Bioorganic chemistry, 2022-06-18;127(0):105977. 2022-06-18 [PMID: 35779404] (Human)		Human
S Zhao, Z Huang, H Jiang, J Xiu, L Zhang, Q Long, Y Yang, L Yu, L Lu, H Gu Sirtuin 1 Induces Choroidal Neovascularization and Triggers Age-Related Macular Degeneration by Promoting LCN2 through SOX9 Deacetylation Oncogene, 2022-06-09;2022(0):1671438. 2022-06-09 [PMID: 35720180] (Human)		Human
MHA Bakar, NSN Shahril, MSFM Khalid, S Mohammad, KA Shariff, T Karunakara, RM Salleh, MN Rosdi Celastrol alleviates high-fat diet-induced obesity via enhanced muscle glucose utilization and mitochondrial oxidative metabolism-mediated upregulation of pyruvate dehydrogenase complex Oncogene, 2022-06-06;449(0):116099. 2022-06-06 [PMID: 35679966] (Mouse)		Mouse
JT de Kay, J Carver, B Shevenell, AM Kosta, S Tsibulniko, E Certo, DB Sawyer, S Ryzhov, MP Robich Decreased expression of ErbB2 on left ventricular epicardial cells in patients with diabetes mellitus Cellular Signalling, 2022-05-21;96(0):110360. 2022-05-21 [PMID: 35609807] (Human)		Human
V Artusa, C Ciaramelli, A D'Aloia, FA Facchini, N Gotri, A Bruno, B Costa, A Palmioli, C Airoldi, F Peri Green and Roasted Coffee Extracts Inhibit Interferon-beta Release in LPS-Stimulated Human Macrophages Frontiers in Pharmacology, 2022-05-05;13(0):806010. 2022-05-05 [PMID: 35600887] (Human)		Human
L Homann, M Rentschler, E Brenner, K Böhm, M Röcken, T Wieder IFN-gamma and TNF Induce Senescence and a Distinct Senescence-Associated Secretory Phenotype in Melanoma Cells, 2022-04-30;11(9):. 2022-04-30 [PMID: 35563820] (Human)		Human
Y Zhan, J Chen, J Wu, Y Gu, Q Huang, Z Deng, S Chen, X Wu, Y Lv, Z Zeng, J Xie Human epididymis protein 4 aggravates airway inflammation and remodeling in chronic obstructive pulmonary disease Respiratory Research, 2022-05-12;23(1):120. 2022-05-12 [PMID: 35550579] (Human)		Human
KN Lee, KH Park, YM Kim, I Cho, TE Kim Prediction of emergency cerclage outcomes in women with cervical insufficiency: The role of inflammatory, angiogenic, and extracellular matrix-related proteins in amniotic fluid PLoS ONE, 2022-05-10;17(5):e0268291. 2022-05-10 [PMID: 35536791] (Human)		Human
MJ Yu, C Li, SS Deng, XM Meng, RS Yao Discovery of a novel GRPR antagonist for protection against cisplatin-induced acute kidney injury Bioorganic chemistry, 2022-04-06;124(0):105794. 2022-04-06 [PMID: 35533545] (Human)		Human
S Novello, S Tricot-Dol, A Novella, P Pellen-Mus, S Jeanne Influence of Periodontal Ligament Stem Cell-Derived Conditioned Medium on Osteoblasts Pharmaceutics, 2022-03-28;14(4):. 2022-03-28 [PMID: 35456563] (Human)		Human
M Lipcsey, M Bergquist, R Sirén, A Larsson, F Huss, J Pravda, M Furebring, J Sjölin, H Janols Urine Hydrogen Peroxide Levels and Their Relation to Outcome in Patients with Sepsis, Septic Shock, and Major Burn Injury Biomedicines, 2022-04-05;10(4):. 2022-04-05 [PMID: 35453598] (Human)		Human
JR McCall, KT Sausman, DM Keeler, AP Brown, SL Turrise Immune Modulating Brevetoxins: Monocyte Cytotoxicity, Apoptosis, and Activation of M1/M2 Response Elements Is Dependent on Reactive Groups Marine Drugs, 2022-03-29;20(4):. 2022-03-29 [PMID: 35447906] (Human)		Human
M Dolci, L Signorini, S D'Alessand, F Perego, S Parapini, M Sommariva, D Taramelli, P Ferrante, N Basilico, S Delbue In Vitro SARS-CoV-2 Infection of Microvascular Endothelial Cells: Effect on Pro-Inflammatory Cytokine and Chemokine Release International Journal of Molecular Sciences, 2022-04-06;23(7):. 2022-04-06 [PMID: 35409421] (Human)		Human
P Esteves, B Allard, A Celle, I Dupin, E Maurat, O Ousova, M Thumerel, JW Dupuy, T Leste-Lass, R Marthan, PO Girodet, T Trian, P Berger Asthmatic bronchial smooth muscle increases rhinovirus replication within the bronchial epithelium Cell Reports, 2022-03-29;38(13):110571. 2022-03-29 [PMID: 35354045] (Human)		Human
J Ohmes, MD Mikkelsen, TT Nguyen, VHN Tran, S Meier, MS Nielsen, M Ding, A Seekamp, AS Meyer, S Fuchs Depolymerization of fucoidan with endo-fucoidanase changes bioactivity in processes relevant for bone regeneration Carbohydrate polymers, 2022-02-24;286(0):119286. 2022-02-24 [PMID: 35337530] (Human)		Human
LM de-Oliveir, VE Fiestas So, M de Lourdes, C Fernandes-, PH Damasco, MAMT de Siqueir, HG Dias, A Pauvolid-C, PV Damasco, EL de Azeredo Comparative Analysis of Circulating Levels of SARS-CoV-2 Antibodies and Inflammatory Mediators in Healthcare Workers and COVID-19 Patients Viruses, 2022-02-23;14(3):. 2022-02-23 [PMID: 35336861] (Human)		Human
E Singh, RAM Osmani, R Banerjee, AS Abu Lila, A Moin, K Almansour, HH Arab, HF Alotaibi, ES Khafagy Poly epsilon-Caprolactone Nanoparticles for Sustained Intra-Articular Immune Modulation in Adjuvant-Induced Arthritis Rodent Model Pharmaceutics, 2022-02-26;14(3):. 2022-02-26 [PMID: 35335895] (Human)		Human
H Farah, SN Wijesinghe, T Nicholson, F Alnajjar, M Certo, A Alghamdi, ET Davis, SP Young, C Mauro, SW Jones Differential Metabotypes in Synovial Fibroblasts and Synovial Fluid in Hip Osteoarthritis Patients Support Inflammatory Responses International Journal of Molecular Sciences, 2022-03-17;23(6):. 2022-03-17 [PMID: 35328687] (Human)		Human
A Divoux, E Erdos, K Whytock, TF Osborne, SR Smith Transcriptional and DNA Methylation Signatures of Subcutaneous Adipose Tissue and Adipose-Derived Stem Cells in PCOS Women Cells, 2022-03-01;11(5):. 2022-03-01 [PMID: 35269469] (Human)		Human
AR Cátala-Val, J Almeda, JN Bernard, AM Cole, AL Cole, SD Moore, CD Andl E-Cigarette Aerosols Promote Oral S. aureus Colonization by Delaying an Immune Response and Bacterial Clearing Cells, 2022-02-23;11(5):. 2022-02-23 [PMID: 35269394] (Human)		Human
G Szylar, R Wysoczansk, H Marshall, DJB Marks, R José, ME Ehrenstein, JS Brown A novel Streptococcus pneumoniae human challenge model demonstrates Treg lymphocyte recruitment to the infection site Scientific Reports, 2022-03-07;12(1):3990. 2022-03-07 [PMID: 35256717] (Human)		Human
S Eslick, EJ Williams, BS Berthon, T Wright, C Karihaloo, M Gately, LG Wood Weight Loss and Short-Chain Fatty Acids Reduce Systemic Inflammation in Monocytes and Adipose Tissue Macrophages from Obese Subjects Nutrients, 2022-02-11;14(4):. 2022-02-11 [PMID: 35215414] (Human)		Human
M O?dakowska, M ?ciskalska, M Kepinska, G Marek, H Milnerowic Association of Genetic Variants in IL6 Gene (rs1800795) with the Concentration of Inflammatory Markers (IL-6, hs-CRP) and Superoxide Dismutase in the Blood of Patients with Acute Pancreatitis-Preliminary Findings Genes, 2022-02-01;13(2):. 2022-02-01 [PMID: 35205334] (Human)		Human
R Gupta, P Gupta, Z Wang, A Seth, J Morrissey, I George, S Gandra, G Storch, B Parikh, G Genin, S Singamanen Plasmon-enhanced Quantitative Lateral Flow Assay for Femtomolar Detection of SARS-CoV-2 Antibodies and Antigens Research square, 2022-02-21;0(0):. 2022-02-21 [PMID: 35194598] (Human)		Human
J Zinngrebe, B Moepps, T Monecke, P Gierschik, F Schlichtig, TFE Barth, G Strau beta , E Boldrin, C Posovszky, A Schulz, O Beringer, E Rieser, EM Jacobsen, MR Lorenz, K Schwarz, U Pannicke, H Walczak, D Niessing, C Schuetz, P Fischer-Po, KM Debatin Compound heterozygous variants in OTULIN are associated with fulminant atypical late-onset ORAS Embo Molecular Medicine, 2022-02-16;0(0):e14901. 2022-02-16 [PMID: 35170849] (Human)		Human
B van der Lu, MCP Vos, M Grootte Br, N Ijssennagg, F Vrieling, J Meijerink, WT Steegenga The effects of sulfated secondary bile acids on intestinal barrier function and immune response in an inflammatory in vitro human intestinal model Heliyon, 2022-02-02;8(2):e08883. 2022-02-02 [PMID: 35169646] (Human)		Human
C Sun, M Janjic Ran, M Folwaczny, T Stocker, S Otto, A Wichelhaus, U Baumert Effect of Different Parameters of In Vitro Static Tensile Strain on Human Periodontal Ligament Cells Simulating the Tension Side of Orthodontic Tooth Movement International Journal of Molecular Sciences, 2022-01-28;23(3):. 2022-01-28 [PMID: 35163446] (Human)		Human
L Leppik, A Gempp, Z Kuçi, S Kuçi, P Bader, H Bönig, I Marzi, D Henrich A New Perspective for Bone Tissue Engineering: Human Mesenchymal Stromal Cells Well-Survive Cryopreservation on beta-TCP Scaffold and Show Increased Ability for Osteogenic Differentiation International Journal of Molecular Sciences, 2022-01-26;23(3):. 2022-01-26 [PMID: 35163348] (Human)		Human
YK Lin, CT Yeh, KT Kuo, IH Fong, VK Yadav, NG Kounis, P Hu, MY Hung Apolipoprotein (a)/Lipoprotein(a)-Induced Oxidative-Inflammatory alpha7-nAChR/p38 MAPK/IL-6/RhoA-GTP Signaling Axis and M1 Macrophage Polarization Modulate Inflammation-Associated Development of Coronary Artery Spasm Oxidative Medicine and Cellular Longevity, 2022-01-19;2022(0):9964689. 2022-01-19 [PMID: 35096275] (Human)		Human
R Pohl, S Feder, EM Haberl, L Rein-Fisch, TS Weiss, M Spirk, A Bruckmann, N McMullen, CJ Sinal, C Buechler Chemerin Overexpression in the Liver Protects against Inflammation in Experimental Non-Alcoholic Steatohepatitis Biomedicines, 2022-01-07;10(1):. 2022-01-07 [PMID: 35052810] (Human)		Human
Y Gu, J Chen, Q Huang, Y Zhan, T Wang, J Wu, J Zhao, Z Zeng, Y Lv, C Xiao, J Xie MTMR14 Alleviates Chronic Obstructive Pulmonary Disease as a Regulator in Inflammation and Emphysema Oxidative Medicine and Cellular Longevity, 2022-01-07;2022(0):9300269. 2022-01-07 [PMID: 35035670] (Human)		Human
P Brandi, L Conejero, FJ Cueto, S Martínez-C, G Dunphy, MJ Gómez, C Relaño, P Saz-Leal, M Enamorado, A Quintas, A Dopazo, J Amores-Ini, C Del Fresno, E Nistal-Vil, C Ardavín, A Nieto, M Casanovas, JL Subiza, D Sancho Trained immunity induction by the inactivated mucosal vaccine MV130 protects against experimental viral respiratory infections Cell Reports, 2022-01-04;38(1):110184. 2022-01-04 [PMID: 34986349] (Human)		Human
J Holl, C Pawlukiani, J Corton Rui, D Groth, K Grubczak, HR Hady, J Dadan, J Reszec, S Czaban, C Kowalewski, M Moniuszko, A Eljaszewic Skin Substitute Preparation Method Induces Immunomodulatory Changes in Co-Incubated Cells through Collagen Modification Pharmaceutics, 2021-12-15;13(12):. 2021-12-15 [PMID: 34959443] (Human)		Human
J Jhun, HS Na, KH Cho, J Kim, YM Moon, SY Lee, JS Lee, AR Lee, SJ Kim, ML Cho, SH Park A green-lipped mussel reduces pain behavior and chondrocyte inflammation and attenuated experimental osteoarthritis progression PLoS ONE, 2021-12-02;16(12):e0259130. 2021-12-02 [PMID: 34855756] (Human)		Human
C Valsecchi, S Croce, A Maltese, L Montagna, E Lenta, A Nevone, M Girelli, P Milani, T Bosoni, M Massa, C Abbà, R Campanelli, J Ripepi, A De Silvest, A Carolei, G Palladini, M Zecca, M Nuvolone, MA Avanzini Bone Marrow Microenvironment in Light-Chain Amyloidosis: In Vitro Expansion and Characterization of Mesenchymal Stromal Cells Biomedicines, 2021-10-22;9(11):. 2021-10-22 [PMID: 34829752] (Human)		Human
JW Kennedy, PM Tsimbouri, P Campsie, S Sood, PG Childs, S Reid, PS Young, DRM Meek, CS Goodyear, MJ Dalby Nanovibrational stimulation inhibits osteoclastogenesis and enhances osteogenesis in co-cultures Scientific Reports, 2021-11-23;11(1):22741. 2021-11-23 [PMID: 34815449] (Human)		Human
JE Lee, KH Park, HJ Kim, YM Kim, JW Choi, S Shin, KN Lee Proteomic identification of novel plasma biomarkers associated with spontaneous preterm birth in women with preterm labor without infection/inflammation PLoS ONE, 2021-10-28;16(10):e0259265. 2021-10-28 [PMID: 34710180] (Human)		Human
N Mazarakis, RA Higgins, J Anderson, ZQ Toh, RB Luwor, KJ Snibson, TC Karagianni, LAH Do, PV Licciardi The effects of the dietary compound L-sulforaphane against respiratory pathogens International journal of antimicrobial agents, 2021-10-22;0(0):106460. 2021-10-22 [PMID: 34695564] (Human)		Human
M Griffiths, J Yang, D Vaidya, M Nies, S Brandal, DD Ivy, F Hickey, K Wolter-War, ED Austin, M Mullen, MW Pauciulo, KA Lutz, EB Rosenzweig, R Hirsch, D Yung, WC Nichols, AD Everett Biomarkers of Pulmonary Hypertension Are Altered in Children With Down Syndrome and Pulmonary Hypertension The Journal of pediatrics, 2021-10-21;0(0):. 2021-10-21 [PMID: 34687693] (Human)		Human
M Lale Ataei, M Karimipour, P Shahabi, R Pashaei-As, E Ebrahimie, M Pashaiasl The Restorative Effect of Human Amniotic Fluid Stem Cells on Spinal Cord Injury Cells, 2021-09-28;10(10):. 2021-09-28 [PMID: 34685545] (Rat)		Rat
CA Minanni, A Machado-Li, RT Iborra, LS Okuda, R de Souza P, MFM Santana, ALA Lira, ER Nakandakar, MLC Côrrea-Gia, M Passarelli Persistent Effect of Advanced Glycated Albumin Driving Inflammation and Disturbances in Cholesterol Efflux in Macrophages Nutrients, 2021-10-17;13(10):. 2021-10-17 [PMID: 34684632] (Human)		Human
SR Bruno, A Kumar, ZF Mark, R Chandrasek, E Nakada, N Chamberlai, B Mihavics, J Walzer, J Cahoon, AE Dixon, B Cunniff, V Anathy DRP1-Mediated Mitochondrial Fission Regulates Lung Epithelial Response to Allergen International Journal of Molecular Sciences, 2021-10-15;22(20):. 2021-10-15 [PMID: 34681784] (Human)		Human
N Yao, T Tretter, P Kvacskay, W Merkt, N Blank, HM Lorenz, LO Tykocinski Targeting of Janus Kinases Limits Pro-Inflammatory but Also Immunosuppressive Circuits in the Crosstalk between Synovial Fibroblasts and Lymphocytes Biomedicines, 2021-10-08;9(10):. 2021-10-08 [PMID: 34680530] (Human)		Human
SC Lean, RL Jones, SA Roberts, AEP Heazell A prospective cohort study providing insights for markers of adverse pregnancy outcome in older mothers BMC pregnancy and childbirth, 2021-10-20;21(1):706. 2021-10-20 [PMID: 34670515] (Human)		Human
N Kim, S Lee, J Kang, TK Kwon, D Khang, SH Kim Gomisin M2 alleviates psoriasis?like skin inflammation by inhibiting inflammatory signaling pathways Molecular Medicine Reports, 2021-10-19;24(6):. 2021-10-19 [PMID: 34664681] (Human)		Human
B Texler, A Zollner, V Reinstadle, SJ Reider, S Macheiner, B Jelusic, A Pfister, C Watschinge, N Przysiecki, H Tilg, H Oberacher, AR Moschen Tofacitinib-Induced Modulation of Intestinal Adaptive and Innate Immunity and Factors Driving Cellular and Systemic Pharmacokinetics Cellular and Molecular Gastroenterology and Hepatology, 2021-10-06;0(0):. 2021-10-06 [PMID: 34624526] (Human)		Human
N Niu, J Yao, RC Bast, AK Sood, J Liu IL-6 promotes drug resistance through formation of polyploid giant cancer cells and stromal fibroblast reprogramming Oncogenesis, 2021-09-29;10(9):65. 2021-09-29 [PMID: 34588424] (Human)		Human
VE Fiestas So, NR da Costa F, CF Dos Santos, G Corrêa, MDC Cipitelli, M Dornelas R, LJ de Souza, PV Damasco, RV da Cunha, FB Dos Santos, LM de Oliveir, EL de Azeredo Different Profiles of Cytokines, Chemokines and Coagulation Mediators Associated with Severity in Brazilian Patients Infected with Dengue Virus Viruses, 2021-09-08;13(9):. 2021-09-08 [PMID: 34578370] (Human)		Human
M Stražar, VP Mourits, VACM Koeken, LCJ de Bree, SJCFM Moorlag, LAB Joosten, R van Crevel, H Vlamakis, MG Netea, RJ Xavier The influence of the gut microbiome on BCG-induced trained immunity Genome Biology, 2021-09-22;22(1):275. 2021-09-22 [PMID: 34551799] (Human)		Human
J Hu, C Wang, X Huang, S Yi, S Pan, Y Zhang, G Yuan, Q Cao, X Ye, H Li Gut microbiota-mediated secondary bile acids regulate dendritic cells to attenuate autoimmune uveitis through TGR5 signaling Cell Reports, 2021-09-21;36(12):109726. 2021-09-21 [PMID: 34551302] (Human)		Human
MS Shaban, C Müller, C Mayr-Buro, H Weiser, J Meier-Soel, BV Albert, A Weber, U Linne, T Hain, I Babayev, N Karl, N Hofmann, S Becker, S Herold, ML Schmitz, J Ziebuhr, M Kracht Multi-level inhibition of coronavirus replication by chemical ER stress Nature Communications, 2021-09-20;12(1):5536. 2021-09-20 [PMID: 34545074] (Human)		Human
S Schlichtne, NH Meyer, IM Yasinska, N Aliu, SM Berger, BF Gibbs, E Fasler-Kan, VV Sumbayev Functional role of galectin-9 in directing human innate immune reactions to Gram-negative bacteria and T cell apoptosis International immunopharmacology, 2021-09-17;100(0):108155. 2021-09-17 [PMID: 34543981] (Human)		Human
N Cappoli, P Aceto, E Tabolacci, D Mezzogori, L Sollazzi, P Navarra, C Dello Russ Effects of remifentanil on human C20 microglial pro-inflammatory activation European review for medical and pharmacological sciences, 2021-08-01;25(16):5268-5274. 2021-08-01 [PMID: 34486703] (Human)		Human
A Laustsen, RM van der Sl, A Gris-Olive, SS Hernández, E Cemalovic, HQ Tang, LH Pedersen, N Uldbjerg, MR Jakobsen, RO Bak Ascorbic acid supports ex vivo generation of plasmacytoid dendritic cells from circulating hematopoietic stem cells Elife, 2021-09-02;10(0):. 2021-09-02 [PMID: 34473049] (Human)		Human
D Reddi, L Durant, D Bernardo, A Noble, NR English, P Hendy, GC Clark, JL Prior, ED Williamson, SC Knight In Vitro Priming of Human T Cells by Dendritic Cells Provides a Screening Tool for Candidate Vaccines for Burkholderia pseudomallei Vaccines, 2021-08-22;9(8):. 2021-08-22 [PMID: 34452057] (Human)		Human
S Ilari, L Vitiello, P Russo, S Proietti, M Mili?, C Muscoli, V Cardaci, C Tomino, G Bonassi, S Bonassi Daily Vegetables Intake and Response to COPD Rehabilitation. The Role of Oxidative Stress, Inflammation and DNA Damage Nutrients, 2021-08-14;13(8):. 2021-08-14 [PMID: 34444947] (Human)		Human
A Thérien, A Cie?lak, M Verreault, M Perreault, J Trottier, S Gobeil, MC Vohl, O Barbier Omega-3 Polyunsaturated Fatty Acid: A Pharmaco-Nutraceutical Approach to Improve the Responsiveness to Ursodeoxycholic Acid Nutrients, 2021-07-29;13(8):. 2021-07-29 [PMID: 34444777] (Human)		Human
E Wirthgen, M Hornschuh, IM Wrobel, C Manteuffel, J Däbritz Mimicking of Blood Flow Results in a Distinct Functional Phenotype in Human Non-Adherent Classical Monocytes Biology, 2021-08-04;10(8):. 2021-08-04 [PMID: 34439980] (Human)		Human
K Wadowska, P B?asiak, A Rzechonek, I Bil-Lula, M ?liwi?ska- New Insights on Old Biomarkers Involved in Tumor Microenvironment Changes and Their Diagnostic Relevance in Non-Small Cell Lung Carcinoma Biomolecules, 2021-08-13;11(8):. 2021-08-13 [PMID: 34439874] (Human)		Human
M Lesouhaiti, M Gregoire, A Gacouin, V Coirier, A Frerou, C Piau, V Cattoir, E Dumontet, M Revest, P Tattevin, A Roisne, JP Verhoye, E Flecher, Y Le Tulzo, K Tarte, JM Tadié Neutrophil function and bactericidal activity against Staphylococcus aureus after cardiac surgery with cardiopulmonary bypass Journal of leukocyte biology, 2021-08-23;0(0):. 2021-08-23 [PMID: 34425029] (Human)		Human
G Dunsmore, EP Rosero, S Shahbaz, DM Santer, J Jovel, P Lacy, S Houston, S Elahi Neutrophils promote T-cell activation through the regulated release of CD44-bound Galectin-9 from the cell surface during HIV infection PloS Biology, 2021-08-19;19(8):e3001387. 2021-08-19 [PMID: 34411088] (Human)		Human
Z Cui, H Dabas, BC Leonard, JV Shiah, JR Grandis, DE Johnson Caspase-8 mutations associated with head and neck cancer differentially retain functional properties related to TRAIL-induced apoptosis and cytokine induction Cell Death & Disease, 2021-08-06;12(8):775. 2021-08-06 [PMID: 34362880] (Human)		Human
JY Park, JS Hyun, JG Jee, SJ Park, D Khang Structural Deformation of MTX Induced by Nanodrug Conjugation Dictate Intracellular Drug Transport and Drug Efficacy International Journal of Nanomedicine, 2021-07-22;16(0):4943-4957. 2021-07-22 [PMID: 34326636] (Human)		Human
T Katopodi, S Petanidis, K Domvri, P Zarogoulid, D Anestakis, C Charalampi, D Tsavlis, C Bai, H Huang, L Freitag, W Hohenforst, D Matthaios, K Porpodis Kras-driven intratumoral heterogeneity triggers infiltration of M2 polarized macrophages via the circHIPK3/PTK2 immunosuppressive circuit Scientific Reports, 2021-07-29;11(1):15455. 2021-07-29 [PMID: 34326381] (Human)		Human
B Falcones, H Sanz-Frail, E Marhuenda, I Mendizábal, I Cabrera-Ag, N Malandain, JJ Uriarte, I Almendros, D Navajas, DJ Weiss, R Farré, J Otero Bioprintable Lung Extracellular Matrix Hydrogel Scaffolds for 3D Culture of Mesenchymal Stromal Cells Polymers, 2021-07-18;13(14):. 2021-07-18 [PMID: 34301107] (Human)		Human
LE Cabrera, PT Pekkarinen, M Alander, KHA Nowlan, NA Nguyen, S Jokiranta, S Kuivanen, A Patjas, S Mero, SH Pakkanen, S Heinonen, A Kantele, O Vapalahti, E Kekäläinen, T Strandin Characterization of low-density granulocytes in COVID-19 PloS Pathogens, 2021-07-06;17(7):e1009721. 2021-07-06 [PMID: 34228753] (Human)		Human
V Mocanu, Z Zhang, EC Deehan, DH Kao, N Hotte, S Karmali, DW Birch, KK Samarasing, J Walter, KL Madsen Fecal microbial transplantation and fiber supplementation in patients with severe obesity and metabolic syndrome: a randomized double-blind, placebo-controlled phase 2 trial Nature Medicine, 2021-07-05;27(7):1272-1279. 2021-07-05 [PMID: 34226737] (Human)		Human
JK Park, S Shon, HJ Yoo, DH Suh, D Bae, J Shin, JH Jun, N Ha, H Song, YI Choi, T Pap, YW Song Inhibition of histone deacetylase 6 suppresses inflammatory responses and invasiveness of fibroblast-like-synoviocytes in inflammatory arthritis Arthritis Research & Therapy, 2021-07-05;23(1):177. 2021-07-05 [PMID: 34225810] (Human)		Human
M Busch, AAM Kämpfer, RPF Schins An inverted in vitro triple culture model of the healthy and inflamed intestine: Adverse effects of polyethylene particles Chemosphere, 2021-06-28;284(0):131345. 2021-06-28 [PMID: 34216924] (Human)		Human
AL Martel, NL Fraleigh, E Picard, JD Lewicky, G Pawelec, H Lee, GW Ma, L Mousavifar, R Roy, HT Le Novel immunomodulatory properties of low dose cytarabine entrapped in a mannosylated cationic liposome International journal of pharmaceutics, 2021-07-01;0(0):120849. 2021-07-01 [PMID: 34216770] (Human)		Human
KEC Blokland, H Habibie, T Borghuis, GJ Teitsma, M Schuliga, BN Melgert, DA Knight, CA Brandsma, SD Pouwels, JK Burgess Regulation of Cellular Senescence Is Independent from Profibrotic Fibroblast-Deposited ECM Cells, 2021-06-29;10(7):. 2021-06-29 [PMID: 34209854] (Human)		Human
J Budzianows, J Hiczkiewic, K ?ojewska, E Kawka, R Rutkowski, K Korybalska Predictors of Early-Recurrence Atrial Fibrillation after Catheter Ablation in Women and Men with Abnormal Body Weight Journal of Clinical Medicine, 2021-06-18;10(12):. 2021-06-18 [PMID: 34207297] (Human)		Human
E Jover, L Matilla, M Garaikoetx, A Fernández-, P Muntendam, F Jaisser, P Rossignol, N López-Andr Beneficial Effects of Mineralocorticoid Receptor Pathway Blockade against Endothelial Inflammation Induced by SARS-CoV-2 Spike Protein Biomedicines, 2021-06-03;9(6):. 2021-06-03 [PMID: 34204890] (Human)		Human
V Mocanu, H Park, J Dang, N Hotte, A Thiesen, M Laffin, H Wang, D Birch, K Madsen Timing of Tributyrin Supplementation Differentially Modulates Gastrointestinal Inflammation and Gut Microbial Recolonization Following Murine Ileocecal Resection Nutrients, 2021-06-17;13(6):. 2021-06-17 [PMID: 34204288] (Mouse)		Mouse
J Xing, X Zhou, M Fang, E Zhang, LJ Minze, Z Zhang DHX15 is required to control RNA virus-induced intestinal inflammation Cell Reports, 2021-06-22;35(12):109205. 2021-06-22 [PMID: 34161762] (Human)		Human
Y Li, C Bax, J Patel, T Vazquez, A Ravishanka, MM Bashir, M Grinnell, D Diaz, VP Werth Plasma-derived DNA containing-extracellular vesicles induce STING-mediated proinflammatory responses in dermatomyositis Theranostics, 2021-05-21;11(15):7144-7158. 2021-05-21 [PMID: 34158841] (Human)		Human
YC Hu, IJ Tsai, HY Hsu, BL Chiang, YH Yang Identification of monoclonal antibodies against human renal glomerular endothelial cells in lupus nephritis that induce endothelial interferon-alpha production Arthritis Research & Therapy, 2021-06-16;23(1):171. 2021-06-16 [PMID: 34134755] (Human)		Human
LG Lima, S Ham, H Shin, EPZ Chai, ESH Lek, RJ Lobb, AF Müller, S Mathivanan, B Yeo, Y Choi, BS Parker, A Möller Tumor microenvironmental cytokines bound to cancer exosomes determine uptake by cytokine receptor-expressing cells and biodistribution Nature Communications, 2021-06-10;12(1):3543. 2021-06-10 [PMID: 34112803] (Human)		Human
CM Yamazaki, A Yamaguchi, Y Anami, W Xiong, Y Otani, J Lee, NT Ueno, N Zhang, Z An, K Tsuchikama Antibody-drug conjugates with dual payloads for combating breast tumor heterogeneity and drug resistance Nature Communications, 2021-06-10;12(1):3528. 2021-06-10 [PMID: 34112795] (Human)		Human
SL Mathiasen, L Gall-Mas, IS Pateras, SDP Theodorou, MRJ Namini, MB Hansen, OCB Martin, CK Vadivel, K Ntostoglou, D Butter, M Givskov, C Geisler, AN Akbar, VG Gorgoulis, T Frisan, N Ødum, T Krejsgaard Bacterial genotoxins induce T�cell senescence Cell Reports, 2021-06-08;35(10):109220. 2021-06-08 [PMID: 34107253] (Human)		Human
CY Wu, WL Fan, YM Chiu, HY Yang, WI Lee, JL Huang Lipopolysaccharide stimulation test on cultured PBMCs assists the discrimination of cryopyrin-associated periodic syndrome from systemic juvenile idiopathic arthritis Scientific Reports, 2021-06-07;11(1):11903. 2021-06-07 [PMID: 34099791] (Human)		Human
M Sueiro-Oli, J Scott, S Gago, D Petrovic, E Kouroussis, J Zivanovic, Y Yu, M Strobel, C Cunha, D Thomson, R Fortune-Gr, S Thusek, P Bowyer, A Beilhack, A Carvalho, E Bignell, MR Filipovic, J Amich Fungal and host protein persulfidation are functionally correlated and modulate both virulence and antifungal response PloS Biology, 2021-06-01;19(6):e3001247. 2021-06-01 [PMID: 34061822] (Human)		Human
MCC Volkweis, GW Neculqueo, RDS Freitas, APA Dagnino, GG Fritscher, TQ Irigaray, MM Campos Psychological symptoms and salivary inflammatory biomarkers in patients with dentofacial deformities: a case-control study Scientific Reports, 2021-05-26;11(1):11083. 2021-05-26 [PMID: 34040126] (Human)		Human
CM Abreu, MT Cerqueira, RP Pirraco, L Gasperini, RL Reis, AP Marques Rescuing key native traits in cultured dermal papilla cells for human hair regeneration Journal of advanced research, 2020-11-04;30(0):103-112. 2020-11-04 [PMID: 34026290] (Human)		Human
L Feng, L Liang, S Zhang, J Yang, Y Yue, X Zhang HMGB1 downregulation in retinal pigment epithelial cells protects against diabetic retinopathy through the autophagy-lysosome pathway Autophagy, 2021-05-24;0(0):1-20. 2021-05-24 [PMID: 34024230] (Rat)		Rat
PK Fazeli, MA Bredella, OG Pachon-Peñ, W Zhao, X Zhang, AT Faje, M Resulaj, SP Polineni, TM Holmes, H Lee, EK O'Donnell, OA MacDougald, MC Horowitz, CJ Rosen, A Klibanski The dynamics of human bone marrow adipose tissue in response to feeding and fasting JCI Insight, 2021-06-22;0(0):. 2021-06-22 [PMID: 33974568] (Human)		Human
L Liang, Q Zhou, L Feng Decreased microRNA-155 in Behcet's disease leads to defective control of autophagy thereby stimulating excessive proinflammatory cytokine production Arthritis Research & Therapy, 2021-05-06;23(1):135. 2021-05-06 [PMID: 33957967] (Human)		Human
N Bozorgmehr, S Mashhouri, E Perez Rose, L Xu, S Shahbaz, W Sligl, M Osman, DJ Kutsogiann, E MacIntyre, CR O'Neil, S Elahi Galectin-9, a Player in Cytokine Release Syndrome and a Surrogate Diagnostic Biomarker in SARS-CoV-2 Infection MBio, 2021-05-04;12(3):. 2021-05-04 [PMID: 33947753] (Human)		Human
T Koudstaal, D van Uden, JAC van Hulst, P Heukels, IM Bergen, LW Geenen, VJM Baggen, AE van den Bo, LM van den To, PP Chandoesin, M Kool, E Boersma, RW Hendriks, KA Boomars Plasma markers in pulmonary hypertension subgroups correlate with patient survival Respiratory Research, 2021-05-04;22(1):137. 2021-05-04 [PMID: 33947407] (Human)		Human
HL Lee, CE Yeum, H Lee, J Oh, JT Kim, WJ Lee, Y Ha, YI Yang, KN Kim Peripheral Nerve-Derived Stem Cell Spheroids Induce Functional Recovery and Repair after Spinal Cord Injury in Rodents International Journal of Molecular Sciences, 2021-04-16;22(8):. 2021-04-16 [PMID: 33923671] (Human)		Human
R Song, Y Gao, I Dozmorov, V Malladi, I Saha, MM McDaniel, S Parameswar, C Liang, C Arana, B Zhang, B Wakeland, J Zhou, MT Weirauch, LC Kottyan, EK Wakeland, C Pasare IRF1 governs the differential interferon-stimulated gene responses in human monocytes and macrophages by regulating chromatin accessibility Cell Reports, 2021-03-23;34(12):108891. 2021-03-23 [PMID: 33761354] (Human)		Human
JH Jeong, SJ Choi, SM Ahn, JS Oh, YG Kim, CK Lee, B Yoo, S Hong Neutrophil extracellular trap clearance by synovial macrophages in gout Arthritis Research & Therapy, 2021-03-19;23(1):88. 2021-03-19 [PMID: 33741037] (Human)		Human
MS Phuong, RE Hernandez, DJ Wolter, LR Hoffman, S Sad Impairment in inflammasome signaling by the chronic Pseudomonas aeruginosa isolates from cystic fibrosis patients results in an increase in inflammatory response Cell Death & Disease, 2021-03-04;12(3):241. 2021-03-04 [PMID: 33664232] (Human)		Human
AYY Tam, AL Horwell, SL Trinder, K Khan, S Xu, V Ong, CP Denton, JT Norman, AM Holmes, G Bou-Ghario, DJ Abraham Selective deletion of connective tissue growth factor attenuates experimentally-induced pulmonary fibrosis and pulmonary arterial hypertension The international journal of biochemistry & cell biology, 2021-03-01;134(0):105961. 2021-03-01 [PMID: 33662577] (Human)		Human
N Jones, J Blagih, F Zani, A Rees, DG Hill, BJ Jenkins, CJ Bull, D Moreira, AIM Bantan, JG Cronin, D Avancini, GW Jones, DK Finlay, KH Vousden, EE Vincent, CA Thornton Fructose reprogrammes glutamine-dependent oxidative metabolism to support LPS-induced inflammation Nature Communications, 2021-02-22;12(1):1209. 2021-02-22 [PMID: 33619282] (Human)		Human
C Vaamonde-G, N Flórez-Fer, MD Torres, MJ Lamas-Vázq, FJ Blanco, H Domínguez, R Meijide-Fa Study of fucoidans as natural biomolecules for therapeutical applications in osteoarthritis Carbohydrate polymers, 2021-01-26;258(0):117692. 2021-01-26 [PMID: 33593565] (Human)		Human
JI Alexander, DB Vendramini, R Francescon, T Luong, J Franco-Bar, N Shah, JC Gardiner, E Nicolas, KS Raghavan, E Cukierman Palladin isoforms 3 and 4 regulate cancer-associated fibroblast pro-tumor functions in pancreatic ductal adenocarcinoma Scientific Reports, 2021-02-15;11(1):3802. 2021-02-15 [PMID: 33589694] (Human)		Human
P Kvacskay, N Yao, JH Schnotz, R Scarpone, RA Carvalho, KD Klika, W Merkt, T Tretter, HM Lorenz, LO Tykocinski Increase of aerobic glycolysis mediated by activated T helper cells drives synovial fibroblasts towards an inflammatory phenotype: new targets for therapy? Arthritis Research & Therapy, 2021-02-15;23(1):56. 2021-02-15 [PMID: 33588937] (Human)		Human
Y Hosokawa, I Hosokawa, K Ozaki, T Matsuo The Polymethoxy Flavonoid Sudachitin Inhibits Interleukin-1&beta-Induced Inflammatory Mediator Production in Human Periodontal Ligament Cells BioMed Research International, 2021-01-28;2021(0):8826586. 2021-01-28 [PMID: 33575345] (Human)		Human
AD Brunaugh, H Seo, Z Warnken, L Ding, SH Seo, HDC Smyth Development and evaluation of inhalable composite niclosamide-lysozyme particles: A broad-spectrum, patient-adaptable treatment for coronavirus infections and sequalae PLoS ONE, 2021-02-11;16(2):e0246803. 2021-02-11 [PMID: 33571320] (Human)		Human
M Dabaghi, N Saraei, G Xu, A Chandiramo, J Yeung, JP Nguyen, M Vukmirovic, PR Selvaganap, JA Hirota PHAIR: a biosensor for pH measurement in air-liquid interface cell culture Scientific Reports, 2021-02-10;11(1):3477. 2021-02-10 [PMID: 33568708] (Human)		Human
X Chu, Y Gu, W Sheng, J Sun, JA Morgan, DF Lewis, DB Cooper, CE McCathran, Y Wang Downregulation of miR-126-3p expression contributes to increased inflammatory response in placental trophoblasts in preeclampsia Journal of reproductive immunology, 2021-02-01;144(0):103281. 2021-02-01 [PMID: 33549904] (Human)		Human
P Jitprasert, M Khamphio, P Petsrichua, VGH Eijsink, W Poolsri, C Muanprasat, K Rangnoi, M Yamabhai Anti-inflammatory activity of soluble chito-oligosaccharides (CHOS) on VitD3-induced human THP-1 monocytes PLoS ONE, 2021-02-03;16(2):e0246381. 2021-02-03 [PMID: 33534833] (Human)		Human
MS Coates, EWFW Alton, GW Rapeport, JC Davies, K Ito Pseudomonas aeruginosa induces p38MAP kinase-dependent IL-6 and CXCL8 release from bronchial epithelial cells via a Syk kinase pathway PLoS ONE, 2021-02-01;16(2):e0246050. 2021-02-01 [PMID: 33524056] (Human)		Human
RP Madeira, LM Dal'Mas Ro, P de Cássia, C Mady, BM Ianni, AC Torrecilha New Biomarker in Chagas Disease: Extracellular Vesicles Isolated from Peripheral Blood in Chronic Chagas Disease Patients Modulate the Human Immune Response Journal of Immunology Research, 2021-01-11;2021(0):6650670. 2021-01-11 [PMID: 33506056] (Human)		Human
Z Iqbal, A Kalteniece, M Ferdousi, S Adam, L D'Onofrio, JH Ho, AP Rao, S Dhage, S Azmi, Y Liu, R Donn, RA Malik, H Soran Corneal Keratocyte Density and Corneal Nerves Are Reduced in Patients With Severe Obesity and Improve After Bariatric Surgery Investigative Ophthalmology & Visual Science, 2021-01-04;62(1):20. 2021-01-04 [PMID: 33475689] (Human)		Human
SM Anil, N Shalev, AC Vinayaka, S Nadarajan, D Namdar, E Belausov, I Shoval, KA Mani, G Mechrez, H Koltai Cannabis compounds exhibit anti-inflammatory activity in vitro in COVID-19-related inflammation in lung epithelial cells and pro-inflammatory activity in macrophages Scientific Reports, 2021-01-14;11(1):1462. 2021-01-14 [PMID: 33446817] (Human)		Human
R Björkenhei, E Jämsen, E Eriksson, P Uppstu, L Aalto-Setä, L Hupa, KK Eklund, M Ainola, NC Lindfors, J Pajarinen Sintered S53P4 bioactive glass scaffolds have anti-inflammatory properties and stimulate osteogenesis in vitro European cells & materials, 2021-01-03;41(0):15-30. 2021-01-03 [PMID: 33389745] (Human)		Human
LJ Williams, SG Tristram, GR Zosky Iron Oxide Particles Alter Bacterial Uptake and the LPS-Induced Inflammatory Response in Macrophages International Journal of Environmental Research and Public Health, 2020-12-28;18(1):. 2020-12-28 [PMID: 33379200] (Human)		Human
P Peterlin, J Gaschet, T Guillaume, A Garnier, M Eveillard, A Le Bourgeo, M Cherel, C Debord, Y Le Bris, O Theisen, C Godon, B Mahé, V Dubruille, S Wuilleme, C Touzeau, T Gastinne, N Blin, A Lok, B Tessoulin, S Le Gouill, P Moreau, MC Béné, P Chevallier A new cytokine-based dynamic stratification during induction is highly predictive of survivals in acute myeloid leukemia Cancer Medicine, 2020-12-25;0(0):. 2020-12-25 [PMID: 33369136] (Human)		Human
H Salvator, A Buenestado, M Brollo, E Naline, T Victoni, E Longchamp, H Tenor, S Grassin-De, P Devillier Clinical Relevance of the Anti-inflammatory Effects of Roflumilast on Human Bronchus: Potentiation by a Long-Acting Beta-2-Agonist Frontiers in Pharmacology, 2020-12-08;11(0):598702. 2020-12-08 [PMID: 33363471] (Human)		Human
M Estermann, YL Huang, D Septiadi, D Ritz, CY Liang, F Jacob, B Drasler, A Petri-Fink, V Heinzelman, B Rothen-Rut Patient-derived and artificial ascites have minor effects on MeT-5A mesothelial cells and do not facilitate ovarian cancer cell adhesion PLoS ONE, 2020-12-03;15(12):e0241500. 2020-12-03 [PMID: 33270665] (Human)		Human
WM Abdelwahab, A Riffey, C Buhl, C Johnson, K Ryter, JT Evans, DJ Burkhart Co-Adsorption of Synthetic Mincle Agonists and Antigen to Silica Nanoparticles for Enhanced Vaccine Activity: A Formulation Approach to Co-Delivery Int J Pharm, 2020-11-27;0(0):120119. 2020-11-27 [PMID: 33249249] (Human)		Human
M De, A Bhushan, S Chinnaswam Monocytes differentiated into macrophages and dendritic cells in the presence of human IFN-&lambda3 or IFN-&lambda4 show distinct phenotypes J Leukoc Biol, 2020-11-17;0(0):. 2020-11-17 [PMID: 33205487] (Human)		Human
CA Ciocan-Car, A Jurj, O Zanoaga, R Cojocneanu, LA Pop, A Moldovan, C Moldovan, AA Zimta, L Raduly, C Pop-Bica, M Buse, L Budisan, P Virag, A Irimie, SMG Diaz, I Berindan-N, C Braicu New insights in gene expression alteration as effect of doxorubicin drug resistance in triple negative breast cancer cells J Exp Clin Cancer Res, 2020-11-13;39(1):241. 2020-11-13 [PMID: 33187552] (Human)		Human
S Hong, JE Lee, YM Kim, Y Park, JW Choi, KH Park Identifying potential biomarkers related to pre-term delivery by proteomic analysis of amniotic fluid Sci Rep, 2020-11-12;10(1):19648. 2020-11-12 [PMID: 33184413] (Human)		Human
A Floudas, N Neto, V Marzaioli, K Murray, B Moran, MG Monaghan, C Low, RH Mullan, N Rao, V Krishna, S Nagpal, DJ Veale, U Fearon Pathogenic, glycolytic PD-1+ B cells accumulate in the hypoxic RA joint JCI Insight, 2020-11-05;5(21):. 2020-11-05 [PMID: 33148884] (Human)		Human
M Kameda, M Otsuka, H Chiba, K Kuronuma, T Hasegawa, H Takahashi, H Takahashi CXCL9, CXCL10, and CXCL11; biomarkers of pulmonary inflammation associated with autoimmunity in patients with collagen vascular diseases-associated interstitial lung disease and interstitial pneumonia with autoimmune features PLoS ONE, 2020-11-02;15(11):e0241719. 2020-11-02 [PMID: 33137121] (Human)		Human
S Niklander, D Bandaru, DW Lambert, KD Hunter ROCK inhibition modulates the senescence-associated secretory phenotype (SASP) in oral keratinocytes FEBS Open Bio, 2020-11-06;0(0):. 2020-11-06 [PMID: 33095981] (Human)		Human
P Pe?an, S Hambalkó, VT Ha, CT Nagy, C Pelyhe, D Lainš?ek, B Kenyeres, GB Brenner, A Görbe, Á Kittel, M Barteková, P Ferdinandy, M Man?ek-Keb, Z Giricz Calcium Ionophore-Induced Extracellular Vesicles Mediate Cytoprotection against Simulated Ischemia/Reperfusion Injury in Cardiomyocyte-Derived Cell Lines by Inducing Heme Oxygenase 1 Int J Mol Sci, 2020-10-16;21(20):. 2020-10-16 [PMID: 33081396] (Human)		Human
M Tutter, C Schug, KA Schmohl, S Urnauer, C Kitzberger, N Schwenk, M Petrini, C Zach, S Ziegler, P Bartenstei, WA Weber, G Multhoff, E Wagner, LH Lindner, PJ Nelson, C Spitzweg Regional hyperthermia enhances mesenchymal stem cell recruitment to tumor stroma: Implications for mesenchymal stem cell-based tumor therapy Mol Ther, 2020-10-15;0(0):. 2020-10-15 [PMID: 33068779] (Human)		Human
CG de Oliveir, MVM de Andrade, LR Guedes, HC Rocha, RG Guimarães, FAC Carvalho, EG Vilela Evaluation of the Biomarkers HMGB1 and IL-6 as Predictors of Mortality in Cirrhotic Patients with Acute Kidney Injury Mediators Inflamm, 2020-09-25;2020(0):2867241. 2020-09-25 [PMID: 33061824] (Human)		Human
T Peeters, S Martens, V D'Onofrio, MHT Stappers, JCH van der Hi, B Houben, R Achten, LAB Joosten, IC Gyssens An observational study of innate immune responses in patients with acute appendicitis Sci Rep, 2020-10-15;10(1):17352. 2020-10-15 [PMID: 33060696] (Human)		Human
HC Hawerkamp, L van Geelen, J Korte, J Di Domizio, M Swidergall, AA Momin, FJ Guzmán-Veg, ST Arold, J Ernst, M Gilliet, R Kalscheuer, B Homey, S Meller Interleukin-26 activates macrophages and facilitates killing of Mycobacterium tuberculosis Sci Rep, 2020-10-14;10(1):17178. 2020-10-14 [PMID: 33057074] (Human)		Human
MA Rahat, M Safieh, E Simanovich, E Pasand, T Gazitt, A Haddad, M Elias, D Zisman The role of EMMPRIN/CD147 in regulating angiogenesis in patients with psoriatic arthritis Arthritis Res Ther, 2020-10-14;22(1):240. 2020-10-14 [PMID: 33054815] (Human)		Human
PM Jordan, J Gerstmeier, S Pace, R Bilancia, Z Rao, F Börner, L Miek, Ó Gutiérrez-, V Arakandy, A Rossi, A Ialenti, C González-E, B Löffler, L Tuchscherr, CN Serhan, O Werz Staphylococcus aureus-Derived &alpha-Hemolysin Evokes Generation of Specialized Pro-resolving Mediators Promoting Inflammation Resolution Cell Rep, 2020-10-13;33(2):108247. 2020-10-13 [PMID: 33053344] (Mouse)		Mouse
F Al-Rashed, Z Ahmad, R Thomas, M Melhem, AJ Snider, LM Obeid, F Al-Mulla, YA Hannun, R Ahmad Neutral sphingomyelinase 2 regulates inflammatory responses in monocytes/macrophages induced by TNF-&alpha Sci Rep, 2020-10-08;10(1):16802. 2020-10-08 [PMID: 33033337] (Human)		Human
M Werner-Kle, A Grujovic, C Irlbeck, M Obradovi?, M Hoffmann, H Koerkel-Qu, X Lu, S Treitschke, C Köstler, C Botteron, K Weidele, C Werno, B Polzer, S Kirsch, M Gužvi?, J Warfsmann, K Honarnejad, Z Czyz, G Feliciello, I Blochberge, S Grunewald, E Schneider, G Haunschild, N Patwary, S Guetter, S Huber, B Rack, N Harbeck, S Buchholz, P Rümmele, N Heine, S Rose-John, CA Klein Interleukin-6 trans-signaling is a candidate mechanism to drive progression of human DCCs during clinical latency Nat Commun, 2020-10-05;11(1):4977. 2020-10-05 [PMID: 33020483] (Human)		Human
YH Kim, MS Kwak, B Lee, JM Shin, S Aum, IH Park, MG Lee, JS Shin Secretory autophagy machinery and vesicular trafficking are involved in HMGB1 secretion Autophagy, 2020-10-05;0(0):1-18. 2020-10-05 [PMID: 33017561] (Mouse)		Mouse
PT Tien, HJ Lin, YY Tsai, YP Lim, CS Chen, CY Chang, CJ Lin, JJ Chen, SM Wu, YJ Huang, L Wan Perfluorooctanoic acid in indoor particulate matter triggers oxidative stress and inflammation in corneal and retinal cells Scientific Reports, 2020-09-24;10(1):15702. 2020-09-24 [PMID: 32973190] (Human)		Human
B Cuffaro, ALW Assohoun, D Boutillier, L Súkeníková, J Desramaut, S Boudebbouz, S Salomé-Des, J Hrdý, AJ Waligora-D, E Maguin, C Grangette In Vitro Characterization of Gut Microbiota-Derived Commensal Strains: Selection of Parabacteroides distasonis Strains Alleviating TNBS-Induced Colitis in Mice Cells, 2020-09-16;9(9):. 2020-09-16 [PMID: 32947881] (Human)		Human
RA Zager, ACM Johnson The NRF2 stimulating agent, tin protoporphyrin, activates protective cytokine pathways in healthy human subjects and in patients with chronic kidney disease Physiol Rep, 2020-09-01;8(18):e14566. 2020-09-01 [PMID: 32940965] (Human)		Human
MFM Santana, ALA Lira, RS Pinto, CA Minanni, ARM Silva, MIBAC Sawada, ER Nakandakar, MLC Correa-Gia, MS Queiroz, GE Ronsein, M Passarelli Enrichment of apolipoprotein A-IV and apolipoprotein D in the HDL proteome is associated with HDL functions in diabetic kidney disease without dialysis Lipids Health Dis, 2020-09-14;19(1):205. 2020-09-14 [PMID: 32921312] (Human)		Human
GJ Britton, A Chen-Liaw, F Cossarini, AE Livanos, MP Spindler, T Plitt, J Eggers, I Mogno, A Gonzalez-R, S Siu, M Tankelevic, L Grinspan, RE Dixon, D Jha, G Martinez-D, F Amanat, DA Hoagland, B tenOever, MC Dubinsky, M Merad, H van Bakel, F Krammer, G Bongers, S Mehandru, JJ Faith SARS-CoV-2-specific IgA and limited inflammatory cytokines are present in the stool of select patients with acute COVID-19 medRxiv : the preprint server for health sciences, 2020-12-09;0(0):. 2020-12-09 [PMID: 32909002] (Human)		Human
A Iannucci, V Caneparo, S Raviola, I Debernardi, D Colangelo, R Miggiano, G Griffante, S Landolfo, M Gariglio, M De Andrea Toll-like receptor 4-mediated inflammation triggered by extracellular IFI16 is enhanced by lipopolysaccharide binding PLoS Pathog., 2020-09-09;16(9):e1008811. 2020-09-09 [PMID: 32903274] (Human)		Human
P Hemström, KH Holmgren, BE Hammarströ, A Larsson, A Östin Identification and toxicological evaluation of cyclic sulfonium ion degradation products of sulphur mustard Mar. Environ. Res., 2020-08-07;162(0):105047. 2020-08-07 [PMID: 32827946] (Human)		Human
B Zhou, DD Wang, Y Qiu, S Airhart, Y Liu, A Stempien-O, KD O'Brien, R Tian Boosting NAD Level Suppresses Inflammatory Activation of PBMC in Heart Failure J. Clin. Invest., 2020-11-02;0(0):. 2020-11-02 [PMID: 32790648] (Human)		Human
M Passariell, C Vetrei, E Sasso, G Froechlich, C Gentile, AM D'Alise, N Zambrano, E Scarselli, A Nicosia, C De Lorenzo Isolation of Two Novel Human Anti-CTLA-4 mAbs with Intriguing Biological Properties on Tumor and NK Cells Cancers (Basel), 2020-08-06;12(8):. 2020-08-06 [PMID: 32781690] (Human)		Human
S Tumpara, B Martinez-D, G Gomez-Mari, B Liu, DS DeLuca, E Korenbaum, D Jonigk, F Jugert, FM Wurm, MJ Wurm, T Welte, S Janciauski The Delivery of &alpha1-Antitrypsin Therapy Through Transepidermal Route: Worthwhile to Explore Front Pharmacol, 2020-07-03;11(0):983. 2020-07-03 [PMID: 32719598] (Human)		Human
AE Wyman, TTT Nguyen, P Karki, ME Tulapurkar, CO Zhang, J Kim, TG Feng, AJ Dabo, NW Todd, IG Luzina, P Geraghty, RF Foronjy, JD Hasday, AA Birukova, SP Atamas, KG Birukov SIRT7 deficiency suppresses inflammation, induces EndoMT, and increases vascular permeability in primary pulmonary endothelial cells Sci Rep, 2020-07-27;10(1):12497. 2020-07-27 [PMID: 32719338] (Human)		Human
A Abbes, Y Zayani, W Zidi, MB Hammami, A Mebazaa, D El Euch, A Ben Ammar, H Sanhaji, MV El May, M Mokni, M Feki, M Allal-Elas Matrix metalloproteinase-7 could be a predictor for acute inflammation in psoriatic patients Cytokine, 2020-07-11;134(0):155195. 2020-07-11 [PMID: 32663776] (Human)		Human
A Strid Holm, CA Jonsson, M Mohaddes, C Lundqvist, H Forsman, I Gjertsson, K Önnheim Data describing expression of formyl peptide receptor 2 in human articular chondrocytes Data Brief, 2020-06-16;31(0):105866. 2020-06-16 [PMID: 32637484] (Human)		Human
J Ma, CC Chan, WC Huang, ML Kuo Berberine Inhibits Pro-inflammatory Cytokine-induced IL-6 and CCL11 Production via Modulation of STAT6 Pathway in Human Bronchial Epithelial Cells Int J Med Sci, 2020-06-08;17(10):1464-1473. 2020-06-08 [PMID: 32624703] (Human)		Human
HF Hazlett, TH Hampton, DS Aridgides, DA Armstrong, JA Dessaint, DL Mellinger, AB Nymon, A Ashare Altered iron metabolism in cystic fibrosis macrophages: the impact of CFTR modulators and implications for Pseudomonas aeruginosa survival Sci Rep, 2020-07-02;10(1):10935. 2020-07-02 [PMID: 32616918] (Human)		Human
T Maekawa, H Tamura, H Domon, T Hiyoshi, T Isono, D Yonezawa, N Hayashi, N Takahashi, K Tabeta, T Maeda, M Oda, A Ziogas, V? Alexaki, T Chavakis, Y Terao, G Hajishenga Erythromycin inhibits neutrophilic inflammation and mucosal disease by upregulating DEL-1 JCI Insight, 2020-08-06;0(0):. 2020-08-06 [PMID: 32603314] (Human)		Human
F Zhang, EA Ayaub, B Wang, E Puchulu-Ca, YH Li, SU Hettiarach, SD Lindeman, Q Luo, S Rout, M Srinivasar, A Cox, K Tsoyi, C Nickerson-, IO Rosas, PS Low Reprogramming of profibrotic macrophages for treatment of bleomycin-induced pulmonary fibrosis EMBO Mol Med, 2020-06-29;0(0):e12034. 2020-06-29 [PMID: 32597014] (Human)		Human
W Abate, H Alrammah, M Kiernan, AJ Tonks, SK Jackson Lysophosphatidylcholine acyltransferase 2 (LPCAT2) co-localises with TLR4 and regulates macrophage inflammatory gene expression in response to LPS Sci Rep, 2020-06-25;10(1):10355. 2020-06-25 [PMID: 32587324] (Human)		Human
E Zuccolo, I Badi, F Scavello, I Gambuzza, L Mancinelli, F Macrì, CC Tedesco, F Veglia, AR Bonfigli, F Olivieri, A Raucci The microRNA-34a-Induced Senescence-Associated Secretory Phenotype (SASP) Favors Vascular Smooth Muscle Cells Calcification Int J Mol Sci, 2020-06-23;21(12):. 2020-06-23 [PMID: 32585876] (Human)		Human
A Allen, N Vaninov, M Li, S Nguyen, P Igo, AW Tilles, B O'Rourke, BLK Miller, B Parekkadan, RN Barcia Mesenchymal Stromal Cell Bioreactor for Ex Vivo Reprogramming of Human Immune Cells Sci Rep, 2020-06-23;10(1):10142. 2020-06-23 [PMID: 32576889] (Human)		Human
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S Gupta, GY Junquera, L Nicassio, B Becknell, CB Ching Trans IL-6 signaling does not appear to play a role in renal scarring after urinary tract infection J Pediatr Urol, 2020-05-29;0(0):. 2020-05-29 [PMID: 32563691] (Human)		Human
N Schwarz, S Tumpara, S Wrenger, E Ercetin, J Hamacher, T Welte, S Janciauski Alpha1-antitrypsin protects lung cancer cells from staurosporine-induced apoptosis: the role of bacterial lipopolysaccharide Sci Rep, 2020-06-12;10(1):9563. 2020-06-12 [PMID: 32533048] (Human)		Human
JH Seo, MH Jin, YH Chang Anti-inflammatory effect of Salsola komarovii extract with dissociated glucocorticoid activity BMC Complement Med Ther, 2020-06-05;20(1):176. 2020-06-05 [PMID: 32503533] (Human)		Human
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M Kohno, K Musashi, HO Ikeda, T Horibe, A Matsumoto, K Kawakami Oral administration of ferulic acid or ethyl ferulate attenuates retinal damage in sodium iodate-induced retinal degeneration mice Sci Rep, 2020-05-26;10(1):8688. 2020-05-26 [PMID: 32457394] (Human)		Human
P B?yszczuk, C Zuppinger, A Costa, D Nurzynska, FD Di Meglio, M Stellato, I Agarkova, GL Smith, O Distler, G Kania Activated Cardiac Fibroblasts Control Contraction of Human Fibrotic Cardiac Microtissues by a beta-Adrenoreceptor-Dependent Mechanism Cells, 2020-05-20;9(5):. 2020-05-20 [PMID: 32443848] (Human)		Human
T O'Loughlin, AJ Kruppa, ALR Ribeiro, JR Edgar, A Ghannam, AM Smith, F Buss OPTN recruitment to a Golgi-proximal compartment regulates immune signalling and cytokine secretion J. Cell. Sci., 2020-06-15;0(0):. 2020-06-15 [PMID: 32376785] (Human)		Human
L Mercurio, CM Failla, L Capriotti, C Scarponi, F Facchiano, M Morelli, S Rossi, G Pagnanelli, C Albanesi, A Cavani, S Madonna Interleukin (IL)-17/IL-36 axis participates to the crosstalk between endothelial cells and keratinocytes during inflammatory skin responses PLoS ONE, 2020-04-30;15(4):e0222969. 2020-04-30 [PMID: 32352958] (Human)		Human
ST Keating, L Groh, CDCC van der He, H Rodriguez, JC Dos Santos, S Fanucchi, J Okabe, H Kaipananic, JH van Puffel, L Helder, MP Noz, V Matzaraki, Y Li, LCJ de Bree, VACM Koeken, SJCFM Moorlag, VP Mourits, J Domínguez-, M Oosting, EP Bulthuis, WJH Koopman, M Mhlanga, A El-Osta, LAB Joosten, MG Netea, NP Riksen The Set7 Lysine Methyltransferase Regulates Plasticity in Oxidative Phosphorylation Necessary for Trained Immunity Induced by &beta-Glucan Cell Rep, 2020-04-21;31(3):107548. 2020-04-21 [PMID: 32320649] (Human)		Human
YH Wang, FM Suk, CL Liu, TL Chen, YC Twu, MH Hsu, YJ Liao Antifibrotic Effects of a Barbituric Acid Derivative on Liver Fibrosis by Blocking the NF-&kappaB Signaling Pathway in Hepatic Stellate Cells Front Pharmacol, 2020-03-31;11(0):388. 2020-03-31 [PMID: 32296336] (Human)		Human
R Gopalakris, H Matta, S Choi, PM Chaudhary Narciclasine, an isocarbostyril alkaloid, has preferential activity against primary effusion lymphoma Sci Rep, 2020-03-31;10(1):5712. 2020-03-31 [PMID: 32235878] (Mouse)		Mouse
W Liu, C Li, FCK Tan, HJ Neo, YH Chan, CM Low, TL Lee Cerebrospinal fluid of chronic osteoarthritic patients induced interleukin-6 release in human glial cell-line T98G BMC Anesthesiol, 2020-03-25;20(1):69. 2020-03-25 [PMID: 32213162] (Human)		Human
JH Ko, HJ Kim, HJ Jeong, HJ Lee, JY Oh Mesenchymal Stem and Stromal Cells Harness Macrophage-Derived Amphiregulin to Maintain Tissue Homeostasis Cell Rep, 2020-03-17;30(11):3806-3820.e6. 2020-03-17 [PMID: 32187551] (Human)		Human
MD Al-Amin, F Bellato, F Mastrotto, M Garofalo, A Malfanti, S Salmaso, P Caliceti Dexamethasone Loaded Liposomes by Thin-Film Hydration and Microfluidic Procedures: Formulation Challenges Int J Mol Sci, 2020-02-26;21(5):. 2020-02-26 [PMID: 32111100] (Human)		Human
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H Kim, S Baek, SM Hong, J Lee, SM Jung, J Lee, M Cho, SK Kwok, SH Park 1,25-dihydroxy Vitamin D3 and Interleukin-6 Blockade Synergistically Regulate Rheumatoid Arthritis by Suppressing Interleukin-17 Production and Osteoclastogenesis J. Korean Med. Sci., 2020-02-17;35(6):e40. 2020-02-17 [PMID: 32056400] (Human)		Human
C Voisin, G Cauchois, L Reppel, C Laroye, L Louarn, C Schenowitz, P Sonon, I Poras, V Wang, E D Carosell, N Benkirane-, P Moreau, N Rouas-Frei, D Bensoussan, C Huselstein Are the Immune Properties of Mesenchymal Stem Cells from Wharton's Jelly Maintained during Chondrogenic Differentiation? J Clin Med, 2020-02-04;9(2):. 2020-02-04 [PMID: 32033151] (Human)		Human
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K Bendí?ková, F Tidu, M De Zuani, MH Kohoutková, I Andrej?ino, A Pompeiano, S B?lášková, G Forte, T Zelante, J Fri? Calcineurin inhibitors reduce NFAT-dependent expression of antifungal pentraxin-3 by human monocytes J. Leukoc. Biol., 2019-04-01;0(0):. 2019-04-01 [PMID: 30934147] (Human)		Human
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F Abdallah, G Lecellier, P Raharivelo, C Pichon R. nukuhivensis acts by reinforcing skin barrier function, boosting skin immunity and by inhibiting IL-22 induced keratinocyte hyperproliferation Sci Rep, 2019-03-11;9(1):4132. 2019-03-11 [PMID: 30858525] (Human)		Human
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AC Passaroni, ML Felicio, NLKL Campos, MAM Silva, WB Yoshida Hemolysis and Inflammatory Response to Extracorporeal Circulation during On-Pump CABG: Comparison between Roller and Centrifugal Pump Systems Braz J Cardiovasc Surg, 2018-01-01;33(1):64-71. 2018-01-01 [PMID: 29617504] (Human)		Human
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DJ Sharkey, DJ Glynn, JE Schjenken, KP Tremellen, SA Robertson Interferon-gamma inhibits seminal plasma induction of colony stimulating factor 2 in mouse and human reproductive tract epithelial cells Biol. Reprod., 2018-09-01;0(0):. 2018-09-01 [PMID: 29596569] (Human)		Human
A Lescoat, A Ballerie, Y Augagneur, C Morzadec, L Vernhet, O Fardel, P Jégo, S Jouneau, V Lecureur Distinct Properties of Human M-CSF and GM-CSF Monocyte-Derived Macrophages to Simulate Pathological Lung Conditions In Vitro: Application to Systemic and Inflammatory Disorders with Pulmonary Involvement Int J Mol Sci, 2018-03-17;19(3):. 2018-03-17 [PMID: 29562615] (Human)		Human
M ?liwi?ska-, S Milnerowic, H Milnerowic Diabetes mellitus secondary to pancreatic diseases (type 3c): The effect of smoking on the exocrine-endocrine interactions of the pancreas Diab Vasc Dis Res, 2018-03-21;0(0):1479164118764. 2018-03-21 [PMID: 29558826] (ELISA Detection, Human)	ELISA Detection	Human
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P Tajpara, C Schuster, E Schön, P Kienzl, M Vierhapper, M Mildner, A Elbe-Bürge Epicutaneous administration of the pattern recognition receptor agonist polyinosinic-polycytidylic acid activates the MDA5/MAVS pathway in Langerhans cells FASEB J., 2018-03-06;0(0):fj201701090R. 2018-03-06 [PMID: 29509510] (Human)		Human
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F Mizoguchi, K Slowikowsk, K Wei, JL Marshall, DA Rao, SK Chang, HN Nguyen, EH Noss, JD Turner, BE Earp, PE Blazar, J Wright, BP Simmons, LT Donlin, GD Kalliolias, SM Goodman, VP Bykerk, LB Ivashkiv, JA Lederer, N Hacohen, PA Nigrovic, A Filer, CD Buckley, S Raychaudhu, MB Brenner Functionally distinct disease-associated fibroblast subsets in rheumatoid arthritis Nat Commun, 2018-02-23;9(1):789. 2018-02-23 [PMID: 29476097] (Human)		Human
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H Peng, D Liang, B Li, C Liang, W Huang, H Lin MicroRNA-320a protects against osteoarthritis cartilage degeneration by regulating the expressions of BMI-1 and RUNX2 in chondrocytes Pharmazie, 2017-04-01;72(4):223-226. 2017-04-01 [PMID: 29441992] (Human)		Human
L Aillot, M Bonnin, M Ait-Gougho, N Bendriss-V, S Maadadi, L Dimier, M Subic, C Scholtes, I Najera, F Zoulim, J Lucifora, D Durantel Interaction between Toll-Like Receptor 9-CpG Oligodeoxynucleotides and Hepatitis B Virus Virions Leads to Entry Inhibition in Hepatocytes and Reduction of Alpha Interferon Production by Plasmacytoid Dendritic Cells Antimicrob. Agents Chemother., 2018-03-27;62(4):. 2018-03-27 [PMID: 29439958] (Human)		Human
CC Wei, YJ Kung, CS Chen, CY Chang, CJ Lin, PT Tien, HY Chang, HJ Chen, YS Huang, HJ Lin, L Wan Allergic Conjunctivitis-induced Retinal Inflammation Promotes Myopia Progression EBioMedicine, 2018-01-31;0(0):. 2018-01-31 [PMID: 29398596] (Human)		Human
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J Batt, M Milward, I Chapple, M Grant, H Roberts, O Addison TiO2 nanoparticles can selectively bind CXCL8 impacting on neutrophil chemotaxis Eur Cell Mater, 2018-01-19;35(0):13-24. 2018-01-19 [PMID: 29350745]
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Y Jiang, L Cheng, X Li, W Zhou, L Zhang Associations between TNFSF4, TNFSF8 and TNFSF15 and Beh�et's disease but not VKH syndrome in Han Chinese Oncotarget, 2017-10-23;8(62):105037-105046. 2017-10-23 [PMID: 29285231] (Human)		Human
A Paunel-Gör, M Wacker, M El Aita, S Hassan, G Schlachten, A Deppe, YH Choi, E Kuhn, TO Mehler, T Wahlers cfDNA correlates with endothelial damage after cardiac surgery with prolonged cardiopulmonary bypass and amplifies NETosis in an intracellular TLR9-independent manner Sci Rep, 2017-12-12;7(1):17421. 2017-12-12 [PMID: 29234042] (Human)		Human
M Mihajlovic, M Fedecostan, MJ Oost, SKP Steenhuis, EGWM Lentjes, I Maitimu-Sm, MJ Janssen, LB Hilbrands, R Masereeuw Role of Vitamin D in Maintaining Renal Epithelial Barrier Function in Uremic Conditions Int J Mol Sci, 2017-11-26;18(12):. 2017-11-26 [PMID: 29186865] (Human)		Human
M ?ciskalska, G Marek, Z Grzebienia, H Milnerowic Resistin as a Prooxidant Factor and Predictor of Endothelium Damage in Patients with Mild Acute Pancreatitis Exposed to Tobacco Smoke Xenobiotics Mediators Inflamm., 2017-09-26;2017(0):3039765. 2017-09-26 [PMID: 29081601] (Human)		Human
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YF Zhao, L Zhu, LJ Liu, SF Shi, JC Lv, H Zhang Pathogenic role of glycan-specific IgG antibodies in IgA nephropathy BMC Nephrol, 2017-09-29;18(1):301. 2017-09-29 [PMID: 28969604] (Human)		Human
S Galland, J Vuille, P Martin, I Letovanec, A Caignard, G Fregni, I Stamenkovi Tumor-Derived Mesenchymal Stem Cells Use Distinct Mechanisms to Block the Activity of Natural Killer Cell Subsets Cell Rep, 2017-09-19;20(12):2891-2905. 2017-09-19 [PMID: 28930684] (Human)		Human
K Eriksson, A Svensson, AS Hait, K Schlüter, P Tunbäck, I Nordström, L Padyukov, JÅ Liljeqvist, TH Mogensen, SR Paludan Cutting Edge: Genetic Association between IFI16 Single Nucleotide Polymorphisms and Resistance to Genital Herpes Correlates with IFI16 Expression Levels and HSV-2-Induced IFN-? Expression J. Immunol., 2017-09-11;0(0):. 2017-09-11 [PMID: 28893956] (Human)		Human
J Ikari, AJ Nelson, J Obaid, A Giron-Mart, K Ikari, F Makino, S Iwasawa, Y Gunji, M Farid, X Wang, H Basma, D Demeo, C Feghali-Bo, O Holz, K Rabe, X Liu, SI Rennard Reduced microRNA-503 expression augments lung fibroblast VEGF production in chronic obstructive pulmonary disease PLoS ONE, 2017-09-07;12(9):e0184039. 2017-09-07 [PMID: 28880936] (Human)		Human
TJJ Schirris, J Jansen, M Mihajlovic, LP van den He, R Masereeuw, FGM Russel Mild intracellular acidification by dexamethasone attenuates mitochondrial dysfunction in a human inflammatory proximal tubule epithelial cell model Sci Rep, 2017-09-06;7(1):10623. 2017-09-06 [PMID: 28878224] (Human)		Human
Z Zeng, M Li, M Wang, X Wu, Q Li, Q Ning, J Zhao, Y Xu, J Xie Increased expression of Siglec-9 in chronic obstructive pulmonary disease Sci Rep, 2017-08-31;7(1):10116. 2017-08-31 [PMID: 28860481] (Human)		Human
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AD Guerra, WE Rose, P Hematti, WJ Kao Minocycline modulates NF?B phosphorylation and enhances antimicrobial activity against Staphylococcus aureus in mesenchymal stromal/stem cells Stem Cell Res Ther, 2017-07-21;8(1):171. 2017-07-21 [PMID: 28732530] (Human)		Human
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A Hongo, N Okumura, M Nakahara, EP Kay, N Koizumi The Effect of a p38 Mitogen-Activated Protein Kinase Inhibitor on Cellular Senescence of Cultivated Human Corneal Endothelial Cells Invest. Ophthalmol. Vis. Sci., 2017-07-01;58(9):3325-3334. 2017-07-01 [PMID: 28672399] (Human)		Human
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A Burban, A Sharanek, R Hüe, M Gay, S Routier, A Guillouzo, C Guguen-Gui Penicillinase-resistant antibiotics induce non-immune-mediated cholestasis through HSP27 activation associated with PKC/P38 and PI3K/AKT signaling pathways Sci Rep, 2017-05-12;7(1):1815. 2017-05-12 [PMID: 28500348] (Human)		Human
N Goli?, K Veljovi?, N Popovi?, J Djoki?, I Strahini?, I Mrvaljevi?, A Terzi?-Vid In vitro and in vivo antagonistic activity of new probiotic culture against Clostridium difficile and Clostridium perfringens BMC Microbiol., 2017-05-06;17(1):108. 2017-05-06 [PMID: 28477627] (Human)		Human
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M Du, A Martin, F Hays, J Johnson, RA Farjo, KM Farjo Serum retinol-binding protein-induced endothelial inflammation is mediated through the activation of toll-like receptor 4 Mol. Vis., 2017-03-31;23(0):185-197. 2017-03-31 [PMID: 28400700] (Human)		Human
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Serum from Varicose Patients Induces Senescence-Related Dysfunction of Vascular Endothelium Generating Local and Systemic Proinflammatory Conditions Oxid Med Cell Longev, 2016-11-23;2016(0):2069290. 2016-11-23 [PMID: 27994710] (Human)		Human
Differential IL-1? secretion by monocyte subsets is regulated by Hsp27 through modulating mRNA stability Sci Rep, 2016-12-15;6(0):39035. 2016-12-15 [PMID: 27976724] (Human)		Human
Marco Santoro MODELING STROMA-INDUCED DRUG RESISTANCE IN A TISSUE-ENGINEERED TUMOR MODEL OF EWING SARCOMA Tissue Eng Part A, 2017-01-01;0(0):. 2017-01-01 [PMID: 27923328] (Human)		Human
CD36-Mediated Uptake of Surfactant Lipids by Human Macrophages Promotes Intracellular Growth of Mycobacterium tuberculosis J. Immunol., 2016-11-09;197(12):4727-4735. 2016-11-09 [PMID: 27913648] (Human)		Human
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Sofia Avnet Cancer-associated mesenchymal stroma fosters the stemness of osteosarcoma cells in response to intratumoral acidosis via NF-?B acivation Int. J. Cancer, 2017-03-15;0(0):. 2017-03-15 [PMID: 27888521] (Human)		Human
Michaela Pekarova Nitro-Oleic Acid Prevents Hypoxia- and Asymmetric Dimethylarginine-Induced Pulmonary Endothelial Dysfunction Cardiovasc Drugs Ther, 2016-12-01;0(0):. 2016-12-01 [PMID: 27858190] (Human)		Human
Tumor-Activated Mesenchymal Stromal Cells Promote Osteosarcoma Stemness and Migratory Potential via IL-6 Secretion PLoS ONE, 2016-11-16;11(11):e0166500. 2016-11-16 [PMID: 27851822] (Human)		Human
Modulating endotoxin activity by combinatorial bioengineering of meningococcal lipopolysaccharide Sci Rep, 2016-11-14;6(0):36575. 2016-11-14 [PMID: 27841285] (Human)		Human
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Essential Oils from Ugandan Medicinal Plants: In Vitro Cytotoxicity and Effects on IL-1?-Induced Proinflammatory Mediators by Human Gingival Fibroblasts Evid Based Complement Alternat Med, 2016-10-11;2016(0):5357689. 2016-10-11 [PMID: 27807462] (Human)		Human
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Stand-Sit Microchip for High-Throughput, Multiplexed Analysis of Single Cancer Cells Sci Rep, 2016-09-01;6(0):32505. 2016-09-01 [PMID: 27581736] (ChIP)	ChIP
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Acanthamoeba castellanii (Genotype T4) Stimulates the Production of Interleukin-10 as well as Pro-inflammatory Cytokines in THP-1 Cells, Human Peripheral Blood Mononuclear Cells and Human Monocyte-Derived Macrophages Infect Immun, 2016-09-19;0(0):. 2016-09-19 [PMID: 27481240] (Human)		Human
DNA Sensing via TLR-9 Constitutes a Major Innate Immunity Pathway Activated during Erythema Nodosum Leprosum J Immunol, 2016-07-29;0(0):. 2016-07-29 [PMID: 27474073] (Human)		Human
Graphene-augmented nanofiber scaffolds demonstrate new features in cells behaviour Sci Rep, 2016-07-22;6(0):30150. 2016-07-22 [PMID: 27443974] (Human)		Human
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Analysis of receptor tyrosine kinase genetics identifies two novel risk loci in GAS6 and PROS1 in Beh�et's disease Sci Rep, 2016-05-25;6(0):26662. 2016-05-25 [PMID: 27222359] (Human)		Human
Engineering a 3D microfluidic culture platform for tumor-treating field application Sci Rep, 2016-05-24;6(0):26584. 2016-05-24 [PMID: 27215466] (Human)		Human
Hepcidin-Induced Iron Deficiency Is Related to Transient Anemia and Hypoferremia in Kawasaki Disease Patients Int J Mol Sci, 2016-05-12;17(5):. 2016-05-12 [PMID: 27187366] (Human)		Human
Intracellular RIG-I Signaling Regulates TLR4-Independent Endothelial Inflammatory Responses to Endotoxin J Immunol, 2016-04-29;196(11):4681-91. 2016-04-29 [PMID: 27183587] (Human)		Human
Comparative Ability of Mesenchymal Stromal Cells from Different Tissues to Limit Neutrophil Recruitment to Inflamed Endothelium PLoS ONE, 2016-05-12;11(5):e0155161. 2016-05-12 [PMID: 27171357] (Human)		Human
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S Robert, T Gicquel, A Bodin, V Lagente, E Boichot Characterization of the MMP/TIMP Imbalance and Collagen Production Induced by IL-1? or TNF-? Release from Human Hepatic Stellate Cells PLoS ONE, 2016-04-05;11(4):e0153118. 2016-04-05 [PMID: 27046197] (Human)		Human
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Ishitsuka K, Hideshima T, Neri P, Vallet S, Shiraishi N, Okawa Y, Shen Z, Raje N, Kiziltepe T, Ocio EM, Chauhan D, Tassone P, Munshi N, Campbell RM, Dios AD, Shih C, Starling JJ, Tamura K, Anderson KC p38 mitogen-activated protein kinase inhibitor LY2228820 enhances bortezomib-induced cytotoxicity and inhibits osteoclastogenesis in multiple myeloma; therapeutic implications. Br. J. Haematol., 2008-04-07;141(5):598-606. 2008-04-07 [PMID: 18397345] (Human)		Human
Aydin S, Signorelli S, Lechleitner T, Joannidis M, Pleban C, Perco P, Pfaller W, Jennings P Influence of microvascular endothelial cells on transcriptional regulation of proximal tubular epithelial cells. Am. J. Physiol., Cell Physiol., 2007-12-05;294(2):C543-54. 2007-12-05 [PMID: 18057119] (Human)		Human
Weindl G, Naglik JR, Kaesler S, Biedermann T, Hube B, Korting HC, Schaller M Human epithelial cells establish direct antifungal defense through TLR4-mediated signaling. J. Clin. Invest., 2007-12-01;117(12):3664-3672. 2007-12-01 [PMID: 17992260] (Human)		Human
Wu T, Xie C, Wang HW, Zhou XJ, Schwartz N, Calixto S, Mackay M, Aranow C, Putterman C, Mohan C Elevated urinary VCAM-1, P-selectin, soluble TNF receptor-1, and CXC chemokine ligand 16 in multiple murine lupus strains and human lupus nephritis. J. Immunol., 2007-11-15;179(10):7166-75. 2007-11-15 [PMID: 17982109] (Human)		Human
Gokhale R, Chandrashekara S, Vasanthakumar KC Cytokine response to strenuous exercise in athletes and non-athletes--an adaptive response. Cytokine, 2007-10-22;40(2):123-7. 2007-10-22 [PMID: 17950614] (Human)		Human
Breitkreutz I, Raab MS, Vallet S, Hideshima T, Raje N, Chauhan D, Munshi NC, Richardson PG, Anderson KC Targeting MEK1/2 blocks osteoclast differentiation, function and cytokine secretion in multiple myeloma. Br. J. Haematol., 2007-10-01;139(1):55-63. 2007-10-01 [PMID: 17854307] (Human)		Human
Birrell MA, Catley MC, Hardaker E, Wong S, Willson TM, McCluskie K, Leonard T, Farrow SN, Collins JL, Haj-Yahia S, Belvisi MG Novel role for the liver X nuclear receptor in the suppression of lung inflammatory responses. J. Biol. Chem., 2007-08-31;282(44):31882-90. 2007-08-31 [PMID: 17766241] (Human)		Human
Birrell MA, Wong S, Catley MC, Belvisi MG Impact of tobacco-smoke on key signaling pathways in the innate immune response in lung macrophages. J. Cell. Physiol., 2008-01-01;214(1):27-37. 2008-01-01 [PMID: 17541958] (Human)		Human
Poulain-Godefroy O, Froguel P Preadipocyte response and impairment of differentiation in an inflammatory environment. Biochem. Biophys. Res. Commun., 2007-03-19;356(3):662-7. 2007-03-19 [PMID: 17383612] (Human)		Human
Harding G, Mak YT, Evans B, Cheung J, MacDonald D, Hampson G The effects of dexamethasone and dehydroepiandrosterone (DHEA) on cytokines and receptor expression in a human osteoblastic cell line: potential steroid-sparing role for DHEA. Cytokine, 2006-12-11;36(1):57-68. 2006-12-11 [PMID: 17161616] (Human)		Human
Kallio R, Sequeiros R, Surcel HM, Ohtonen P, Kiviniemi H, Syrjala H Early cytokine responses after percutaneous magnetic resonance imaging guided laser thermoablation of malignant liver tumors. Cytokine, 2006-07-25;34(5):278-83. 2006-07-25 [PMID: 16870467] (Human)		Human
Macagno A, Molteni M, Rinaldi A A cyanobacterial LPS antagonist prevents endotoxin shock and blocks sustained TLR4 stimulation required for cytokine expression. J. Exp. Med., 2006-05-22;203(6):1481-92. 2006-05-22 [PMID: 16717116] (Human)		Human
Birrell MA, Wong S, Dekkak A, De Alba J, Haj-Yahia S, Belvisi MG Role of matrix metalloproteinases in the inflammatory response in human airway cell-based assays and in rodent models of airway disease. J. Pharmacol. Exp. Ther., 2006-05-11;318(2):741-50. 2006-05-11 [PMID: 16690722] (Human)		Human
Hung MJ, Cherng WJ, Cheng CW, Li LF Comparison of serum levels of inflammatory markers in patients with coronary vasospasm without significant fixed coronary artery disease versus patients with stable angina pectoris and acute coronary syndromes with significant fixed coronary artery disease. Am. J. Cardiol., 2006-03-27;97(10):1429-34. 2006-03-27 [PMID: 16679078] (Human)		Human
Salaun B, Coste I, Rissoan MC, Lebecque SJ, Renno T TLR3 can directly trigger apoptosis in human cancer cells. J. Immunol., 2006-04-15;176(8):4894-901. 2006-04-15 [PMID: 16585585] (Human)		Human
LeBouder E, Rey-Nores JE, Raby AC, Affolter M, Vidal K, Thornton CA, Labeta MO Modulation of neonatal microbial recognition: TLR-mediated innate immune responses are specifically and differentially modulated by human milk. J. Immunol., 2006-03-15;176(6):3742-52. 2006-03-15 [PMID: 16517743] (Human)		Human
Karadag A, Zhou M, Croucher PI ADAM-9 (MDC-9/meltrin-gamma), a member of the a disintegrin and metalloproteinase family, regulates myeloma-cell-induced interleukin-6 production in osteoblasts by direct interaction with the alpha(v)beta5 integrin. Blood, 2005-12-22;107(8):3271-8. 2005-12-22 [PMID: 16373656] (Human)		Human
Lignell U, Meklin T, Putus T, Vepsalainen A, Roponen M, Torvinen E, Reeslev M, Pennanen S, Hirvonen MR, Kalliokoski P, Nevalainen A Microbial exposure, symptoms and inflammatory mediators in nasal lavage fluid of kitchen and clerical personnel in schools. Int J Occup Med Environ Health, 2005-01-01;18(2):139-50. 2005-01-01 [PMID: 16201205] (Human)		Human
Fritz JH, Girardin SE, Fitting C, Werts C, Mengin-Lecreulx D, Caroff M, Cavaillon JM, Philpott DJ, Adib-Conquy M Synergistic stimulation of human monocytes and dendritic cells by Toll-like receptor 4 and NOD1- and NOD2-activating agonists. Eur. J. Immunol., 2005-08-01;35(8):2459-70. 2005-08-01 [PMID: 16021602] (Human)		Human
Palmer G, Trolliet S, Talabot-Ayer D, Mezin F, Magne D, Gabay C Pre-interleukin-1alpha expression reduces cell growth and increases interleukin-6 production in SaOS-2 osteosarcoma cells: Differential inhibitory effect of interleukin-1 receptor antagonist (icIL-1Ra1). Cytokine, 2005-07-21;31(2):153-60. 2005-07-21 [PMID: 15923123] (Human)		Human
Miranda-Carus ME, Balsa A, Benito-Miguel M, Perez de Ayala C, Martin-Mola E IL-15 and the initiation of cell contact-dependent synovial fibroblast-T lymphocyte cross-talk in rheumatoid arthritis: effect of methotrexate. J. Immunol., 2004-07-15;173(2):1463-76. 2004-07-15 [PMID: 15240743] (Human)		Human
Fusshoeller A, Plail M, Grabensee B, Plum J Biocompatibility pattern of a bicarbonate/lactate-buffered peritoneal dialysis fluid in APD: a prospective, randomized study. Nephrol. Dial. Transplant., 2004-06-22;19(8):2101-6. 2004-06-22 [PMID: 15213322] (Human)		Human
Purokivi M, Hirvonen MR, Roponen M, Randell J, Vahteristo M, Tukiainen H Comparison of inflammatory elements in nasal lavage and induced sputum following occupational exposure to moldy-building microbes. Inhal Toxicol, 2002-06-01;14(6):653-62. 2002-06-01 [PMID: 12119074] (Human)		Human
Cheong YC, Laird SM, Shelton JB, Ledger WL, Li TC, Cooke ID The correlation of adhesions and peritoneal fluid cytokine concentrations: a pilot study. Hum. Reprod., 2002-04-01;17(4):1039-45. 2002-04-01 [PMID: 11925402] (Human)		Human
Cheong YC, Shelton JB, Laird SM, Richmond M, Kudesia G, Li TC, Ledger WL IL-1, IL-6 and TNF-alpha concentrations in the peritoneal fluid of women with pelvic adhesions. Hum. Reprod., 2002-01-01;17(1):69-75. 2002-01-01 [PMID: 11756364] (Human)		Human
Roponen M, Kiviranta J, Seuri M, Tukiainen H, Myllykangas-Luosujarvi R, Hirvonen MR Inflammatory mediators in nasal lavage, induced sputum and serum of employees with rheumatic and respiratory disorders. Eur. Respir. J., 2001-09-01;18(3):542-8. 2001-09-01 [PMID: 11589353] (Human)		Human
Purokivi M, Randell J, Hirvonen MR, Tukiainen H Reproducibility of measurements of exhaled NO, and cell count and cytokine concentrations in induced sputum. Eur. Respir. J., 2000-08-01;16(2):242-6. 2000-08-01 [PMID: 10968498] (Human)		Human
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Array DY206

• IL-6 Antibodies
• IL-6 Antibody Pair
• IL-6 ELISA Kits
• IL-6 Lysate
• IL-6 Proteins
• IL-6 Proteins and Enzymes
• IL-6 ELISAs