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HLA ABC Antibody (YTH862.2) [mFluor Violet 500 SE]

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HLA ABC Antibody (YTH862.2) [mFluor Violet 500 SE] - Vial of mFluor Violet 500 conjugated antibody. mFluor Violet 500 is optimally excited at 410 nm by the Violet laser (405 nm) and has an emission maximum of 501 nm.
HLA ABC Antibody (YTH862.2) [mFluor Violet 500 SE] - Vial of mFluor Violet 500 conjugated antibody. mFluor Violet 500 is optimally excited at 410 nm by the Violet laser (405 nm) and has an emission maximum of 501 nm.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, ICC/IF, IHC, IP
Clone
YTH862.2
Clonality
Monoclonal
Host
Rat
Conjugate
mFluor Violet 500 SE

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NB100-65411AF350
Alexa Fluor 405
NB100-65411AF405
Alexa Fluor 488
NB100-65411AF488
Alexa Fluor 532
NB100-65411AF532
Alexa Fluor 594
NB100-65411AF594
Alexa Fluor 647
NB100-65411AF647
Alexa Fluor 700
NB100-65411AF700
Alexa Fluor 750
NB100-65411AF750
Allophycocyanin
NB100-65411APC
Allophycocyanin/Cy7
NB100-65411APCCY7
Biotin
NB100-65411B
CoraFluor 1
NB100-65411CL1
DyLight 350
NB100-65411UV
DyLight 405
NB100-65411V
DyLight 488
NB100-65411G
DyLight 550
NB100-65411R
DyLight 594
NB100-65411DL594
DyLight 650
NB100-65411C
DyLight 680
NB100-65411FR
DyLight 755
NB100-65411IR
FITC
NB100-65411F
HRP
NB100-65411H
Janelia Fluor 525
NB100-65411JF525
Janelia Fluor 549
NB100-65411JF549
Janelia Fluor 585
NB100-65411JF585
Janelia Fluor 635
NB100-65411JF635
Janelia Fluor 646
NB100-65411JF646
Janelia Fluor 669
NB100-65411JF669
PE
NB100-65411PE
PE/Atto594
NB100-65411PEATT594
PE/Cy5.5
NB100-65411PECY55
PE/Cy7
NB100-65411PECY7
PerCP
NB100-65411PCP
Unconjugated
NB100-65411
mFluor Violet 450 SE
NB100-65411MFV450
mFluor Violet 610 SE
NB100-65411MFV610
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HLA ABC Antibody (YTH862.2) [mFluor Violet 500 SE] Summary

Immunogen
PHA activated human peripheral blood lymphocytes
Specificity
NB100-65411 recognizes a monomorphic determinant on the human HLA Class I heavy chain. Epitope analysis has shown that this antibody binds in the alpha1 domain. MHC Class I is expressed by all nucleated cells. Recent studies have shown that this antibody may be able to induce apoptosis in activated but not resting T cells (1).
Isotype
IgG2b
Clonality
Monoclonal
Host
Rat
Gene
HLA-A
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Immunoprecipitation
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for HLA ABC Antibody (YTH862.2) [mFluor Violet 500 SE]

  • A-10 alpha chain
  • FLJ26655
  • HLA class I histocompatibility antigen, A-1 alpha chain
  • HLA class I histocompatibility antigen, A-28 alpha chain
  • HLA class I histocompatibility antigen, A-9 alpha chain
  • HLAA
  • major histocompatibility complex, class I, A
  • MHC class I antigen A*1
  • MHC class I antigen A*11
  • MHC class I antigen A*80

Background

HLA CLass I is involved in the presentation of foreign antigens to the immune system. HLA-class I antigens are widely distributed on human nucleated cells. The intensity of HLA-ABC maybe altered in pathological states e.g. malignant cells may loose HLA-ABC, whereas hepatocytes in alcoholic hepatitis, biliary cirrhosis and chronic active hepatitis may show enhanced expression of HLA-ABC.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol HLA-A