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gp130/CD130 Antibody (745314) [CoraFluor™ 1]

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Product Details

Summary
Reactivity RtSpecies Glossary
Applications WB, Flow, CyTOF-ready
Clone
745314
Clonality
Monoclonal
Host
Mouse
Conjugate
CoraFluor 1

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB5029U-100UG
Alexa Fluor 405
FAB5029V-100UG
Alexa Fluor 488
FAB5029G-100UG
Alexa Fluor 532
FAB5029X
Alexa Fluor 594
FAB5029T-100UG
Alexa Fluor 647
FAB5029R-100UG
Alexa Fluor 700
FAB5029N-100UG
Alexa Fluor 750
FAB5029S-100UG
Allophycocyanin/Cy7
FAB5029APCCY7
Biotin
FAB5029B
DyLight 350
FAB5029D
DyLight 405
FAB5029E
DyLight 488
FAB5029K
DyLight 550
FAB5029L
DyLight 594
FAB5029M
DyLight 650
FAB5029W
DyLight 680
FAB5029Y
DyLight 755
FAB5029Z
FITC
FAB5029F
HRP
FAB5029H
Janelia Fluor 525
FAB5029JF525
Janelia Fluor 549
FAB5029I
Janelia Fluor 585
FAB5029JF585
Janelia Fluor 635
FAB5029JF635
Janelia Fluor 646
FAB5029J
Janelia Fluor 669
FAB5029JF669
PE
FAB5029P
PE/Atto594
FAB5029PEATT594
PE/Cy5.5
FAB5029PECY55
PE/Cy7
FAB5029PECY7
PerCP
FAB5029C
Unconjugated
MAB5029
mFluor Violet 450 SE
FAB5029MFV450
mFluor Violet 500 SE
FAB5029MFV500
mFluor Violet 610 SE
FAB5029MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB5029
Carrier Free
MAB5029
Carrier Free
MAB5029-SP
Carrier Free
FAB5029V-100UG
Carrier Free
FAB5029U-100UG
Carrier Free
FAB5029T-100UG
Carrier Free
FAB5029S-100UG
Carrier Free
FAB5029R-100UG
Carrier Free
FAB5029N-100UG
Carrier Free
FAB5029G-100UG
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gp130/CD130 Antibody (745314) [CoraFluor™ 1] Summary

Description
CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(IM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.
Immunogen
Mouse myeloma cell line NS0-derived recombinant rat gp130
Gln23-Glu618 (predicted)
Accession # P40190
Specificity
Detects rat gp130 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human or recombinant mouse gp130 is observed.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
IL6ST
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark. Do not freeze.
Buffer
PBS
Preservative
No Preservative
Purity
Protein A or G purified

Notes

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

Alternate Names for gp130/CD130 Antibody (745314) [CoraFluor™ 1]

  • CD130 antigen
  • CD130
  • CDw130
  • DKFZp564F053
  • gp130 of the rheumatoid arthritis antigenic peptide-bearing soluble form
  • gp130
  • IL-6 receptor subunit beta
  • IL-6R subunit beta
  • IL-6RB
  • IL-6R-beta
  • IL6ST
  • interleukin 6 signal transducer (gp130, oncostatin M receptor)
  • interleukin receptor beta chain
  • interleukin-6 receptor subunit beta
  • Interleukin-6 signal transducer
  • Membrane glycoprotein 130
  • membrane glycoprotein gp130
  • Oncostatin-M receptor subunit alpha

Background

CD130 is encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggested a critical role of the gene encoding this protein in regulating myocyte apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol IL6ST