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gp130/CD130 Antibody (28126) [PE/Cy7]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
28126
Clonality
Monoclonal
Host
Mouse
Conjugate
PE/Cy7

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB228U-100UG
Alexa Fluor 405
FAB228V-100UG
Alexa Fluor 488
FAB228G-100UG
Alexa Fluor 532
FAB228X
Alexa Fluor 594
FAB228T-100UG
Alexa Fluor 647
FAB228R-100UG
Alexa Fluor 700
FAB228N-100UG
Alexa Fluor 750
FAB228S-100UG
Allophycocyanin
FAB228A-025
Allophycocyanin
FAB228A-100
Allophycocyanin/Cy7
FAB228APCCY7
Biotin
FAB228B
CoraFluor 1
FAB228CL1
DyLight 350
FAB228D
DyLight 405
FAB228E
DyLight 488
FAB228K
DyLight 550
FAB228L
DyLight 594
FAB228M
DyLight 650
FAB228W
DyLight 680
FAB228Y
DyLight 755
FAB228Z
Fluorescein
FAB228F-100
Fluorescein
FAB228F-025
HRP
FAB228H
Janelia Fluor 525
FAB228JF525
Janelia Fluor 549
FAB228I
Janelia Fluor 585
FAB228JF585
Janelia Fluor 635
FAB228JF635
Janelia Fluor 646
FAB228J
Janelia Fluor 669
FAB228JF669
PE/Atto594
FAB228PEATT594
PE/Cy5.5
FAB228PECY55
Phycoerythrin
FAB228P-025
Phycoerythrin
FAB228P-100
Unconjugated
MAB228-100
mFluor Violet 450 SE
FAB228MFV450
mFluor Violet 500 SE
FAB228MFV500
mFluor Violet 610 SE
FAB228MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB228-100
Carrier Free
MAB228-100
Carrier Free
FAB228G-100UG
Carrier Free
FAB228R-100UG
Carrier Free
FAB228S-100UG
Carrier Free
FAB228T-100UG
Carrier Free
FAB228U-100UG
Carrier Free
FAB228V-100UG
Carrier Free
MAB228-500
Carrier Free
FAB228F-100
Carrier Free
MAB228-SP
Carrier Free
FAB228P-025
Carrier Free
FAB228F-025
Carrier Free
FAB228A-025
Carrier Free
FAB228A-100
Carrier Free
FAB228P-100
Carrier Free
FAB228N-100UG
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gp130/CD130 Antibody (28126) [PE/Cy7] Summary

Immunogen
S. frugiperda insect ovarian cell line Sf 21-derived recombinant human gp130 extracellular domain
Specificity
Detects human gp130 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human (rh) IL-2 R, rhIL-4 R, or rhIL-6 R is observed.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
IL6ST
Purity
Protein A or G purified from ascites
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
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Applications/Dilutions

Dilutions
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined. For optimal results using our Tandem dyes, please avoid prolonged exposure to light or extreme temperature fluctuations. These can lead to irreversible degradation or decoupling. When staining intracellular targets, specific attention to the fixation and permeabilization steps in your flow protocol may be required. Please contact our technical support team at technical@novusbio.com if you have any questions.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark. Do not freeze.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from ascites

Alternate Names for gp130/CD130 Antibody (28126) [PE/Cy7]

  • CD130 antigen
  • CD130
  • CDw130
  • DKFZp564F053
  • gp130 of the rheumatoid arthritis antigenic peptide-bearing soluble form
  • gp130
  • IL-6 receptor subunit beta
  • IL-6R subunit beta
  • IL-6RB
  • IL-6R-beta
  • IL6ST
  • interleukin 6 signal transducer (gp130, oncostatin M receptor)
  • interleukin receptor beta chain
  • interleukin-6 receptor subunit beta
  • Interleukin-6 signal transducer
  • Membrane glycoprotein 130
  • membrane glycoprotein gp130
  • Oncostatin-M receptor subunit alpha

Background

CD130 is encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggested a critical role of the gene encoding this protein in regulating myocyte apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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gp130/CD130
Antibody (28126) [PE/
FAB228PECY7
gp130/CD130 Antibody (28126) [PE/Cy7]
Species: Hu
Applications: Flow

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Bioinformatics

Gene Symbol IL6ST