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gp130/CD130 Antibody (125623) [DyLight 550]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications Flow, CyTOF-ready, ICC/IF
Clone
125623
Clonality
Monoclonal
Host
Rat
Conjugate
DyLight 550

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB4681U-100UG
Alexa Fluor 405
FAB4681V-100UG
Alexa Fluor 488
FAB4681G-100UG
Alexa Fluor 532
FAB4681X
Alexa Fluor 594
FAB4681T-100UG
Alexa Fluor 647
FAB4681R-100UG
Alexa Fluor 700
FAB4681N-100UG
Alexa Fluor 750
FAB4681S-100UG
Allophycocyanin
FAB4681A-025UG
Allophycocyanin
FAB4681A-100UG
Allophycocyanin/Cy7
FAB4681APCCY7
Biotin
BAM4681
CoraFluor 1
FAB4681CL1
DyLight 350
FAB4681D
DyLight 405
FAB4681E
DyLight 488
FAB4681K
DyLight 594
FAB4681M
DyLight 650
FAB4681W
DyLight 680
FAB4681Y
DyLight 755
FAB4681Z
FITC
FAB4681F
HRP
FAB4681H
Janelia Fluor 525
FAB4681JF525
Janelia Fluor 549
FAB4681I
Janelia Fluor 585
FAB4681JF585
Janelia Fluor 635
FAB4681JF635
Janelia Fluor 646
FAB4681J
Janelia Fluor 669
FAB4681JF669
PE/Atto594
FAB4681PEATT594
PE/Cy5.5
FAB4681PECY55
PE/Cy7
FAB4681PECY7
PerCP
FAB4681C
Unconjugated
MAB4681
mFluor Violet 450 SE
FAB4681MFV450
mFluor Violet 500 SE
FAB4681MFV500
mFluor Violet 610 SE
FAB4681MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB4681
Carrier Free
MAB4681
Carrier Free
MAB4681-SP
Carrier Free
FAB4681V-100UG
Carrier Free
FAB4681U-100UG
Carrier Free
FAB4681T-100UG
Carrier Free
FAB4681S-100UG
Carrier Free
FAB4681R-100UG
Carrier Free
FAB4681N-100UG
Carrier Free
FAB4681G-100UG
Carrier Free
FAB4681A-100UG
Carrier Free
FAB4681A-025UG
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gp130/CD130 Antibody (125623) [DyLight 550] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse gp130
Gln23-Glu617 (predicted)
Accession # Q6PDI9
Specificity
Detects mouse gp130 in direct ELISAs and Western blots. In Western blots, no cross-reactivity with recombinant human gp130 is observed.
Isotype
IgG2a
Clonality
Monoclonal
Host
Rat
Gene
IL6ST
Purity
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
  • Immunocytochemistry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for gp130/CD130 Antibody (125623) [DyLight 550]

  • CD130 antigen
  • CD130
  • CDw130
  • DKFZp564F053
  • gp130 of the rheumatoid arthritis antigenic peptide-bearing soluble form
  • gp130
  • IL-6 receptor subunit beta
  • IL-6R subunit beta
  • IL-6RB
  • IL-6R-beta
  • IL6ST
  • interleukin 6 signal transducer (gp130, oncostatin M receptor)
  • interleukin receptor beta chain
  • interleukin-6 receptor subunit beta
  • Interleukin-6 signal transducer
  • Membrane glycoprotein 130
  • membrane glycoprotein gp130
  • Oncostatin-M receptor subunit alpha

Background

CD130 is encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggested a critical role of the gene encoding this protein in regulating myocyte apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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gp130/CD130
Antibody (125623) [Dy ...
FAB4681L
gp130/CD130 Antibody (125623) [DyLight 550]
Species: Mu
Applications: Flow, CyTOF-ready, ICC/IF

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Bioinformatics

Gene Symbol IL6ST