gamma-Synuclein Antibody (1H10D2) - BSA Free Summary
Immunogen |
Purified recombinant fragment of gamma-Synuclein expressed in E. Coli. |
Specificity |
SNCG (1H10D2) |
Isotype |
IgG1 |
Clonality |
Monoclonal |
Host |
Mouse |
Gene |
SNCG |
Purity |
Protein G purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- ELISA 1:10000
- Immunohistochemistry 1:10-1:500
- Immunohistochemistry-Paraffin 1:200-1:1000
- Western Blot 1: 500-1: 2000
|
Packaging, Storage & Formulations
Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Buffer |
PBS |
Preservative |
0.03% Sodium Azide |
Purity |
Protein G purified |
Alternate Names for gamma-Synuclein Antibody (1H10D2) - BSA Free
Background
gamma-Synuclein Antibody (1H10D2)(also designated gamma-synuclein or breast cancer-specific protein 1),with 127-amino acid protein(about 14kDa), belongs to the synuclein family, which also includes alpha- and beta- synuclein.Three synucleins are located in the neuronal cytosol and enriched in presynaptic terminals,while gamma-Synuclein Antibody (1H10D2) is also expressed in many other non-neuronal tissues. SNCG is abnormally expressed in a high percentage of tumor tissues of diversified cancer types, including liver, esophagus, colon, gastric, lung, prostate, cervical, and breast cancer, but rarely expressed in tumor-matched nonneoplastic adjacent tissues. High levels of gamma-Synuclein Antibody (1H10D2) have been identified in advanced breast carcinomas suggesting a correlation between overexpression of SNCG and breast tumor development.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Secondary Antibodies
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