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gamma-Synuclein Antibody (1H10D2) - BSA Free

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Western Blot: gamma-Synuclein Antibody (1H10D2) [NB110-60497] - Analysis using mouse mAb against truncated SNCG recombinant protein.
Immunohistochemistry-Paraffin: gamma-Synuclein Antibody (1H10D2) [NB110-60497] - Analysis of human ovary carcinoma (left) and breast carcinoma (right), showing cytoplasmic(ovary carcinoma) localization, cytoplasmic and ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, IHC
Clone
1H10D2
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Format
BSA Free

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gamma-Synuclein Antibody (1H10D2) - BSA Free Summary

Immunogen
Purified recombinant fragment of gamma-Synuclein expressed in E. Coli.
Specificity
SNCG (1H10D2)
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
SNCG
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA 1:10000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:200-1:1000
  • Western Blot 1: 500-1: 2000

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.03% Sodium Azide
Purity
Protein G purified

Alternate Names for gamma-Synuclein Antibody (1H10D2) - BSA Free

  • BCSG1
  • BCSG1PERSYN
  • Breast cancer-specific gene 1 protein
  • gamma-Synuclein
  • persyn
  • PRSN
  • SNCG
  • SRPRSN
  • Synoretin
  • synuclein, gamma (breast cancer-specific protein 1)
  • Synuclein-gamma

Background

gamma-Synuclein Antibody (1H10D2)(also designated gamma-synuclein or breast cancer-specific protein 1),with 127-amino acid protein(about 14kDa), belongs to the synuclein family, which also includes alpha- and beta- synuclein.Three synucleins are located in the neuronal cytosol and enriched in presynaptic terminals,while gamma-Synuclein Antibody (1H10D2) is also expressed in many other non-neuronal tissues. SNCG is abnormally expressed in a high percentage of tumor tissues of diversified cancer types, including liver, esophagus, colon, gastric, lung, prostate, cervical, and breast cancer, but rarely expressed in tumor-matched nonneoplastic adjacent tissues. High levels of gamma-Synuclein Antibody (1H10D2) have been identified in advanced breast carcinomas suggesting a correlation between overexpression of SNCG and breast tumor development.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol SNCG