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gamma Sarcoglycan Antibody (SR3511)

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Western Blot: gamma Sarcoglycan Antibody (SR3511) [NBP3-27778] - Western blot analysis of gamma Sarcoglycan expression in Human skeletal muscle lysate.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC, IP
Clone
SR3511
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

gamma Sarcoglycan Antibody (SR3511) Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
A synthesized peptide derived from human gamma Sarcoglycan (Uniprot #: Q13326)
Specificity
Detects endogenous levels of total gamma Sarcoglycan
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
SGCG
Purity
Affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:50-1:200
  • Immunoprecipitation 1:50
  • Western Blot 1:500-1:2000
Theoretical MW
32 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4), 150mM NaCl, 50% glycerol
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for gamma Sarcoglycan Antibody (SR3511)

  • 35 kDa dystrophin-associated glycoprotein
  • 35DAG
  • A4
  • DAGA4
  • DAGA4,35kD dystrophin-associated glycoprotein
  • DMDA
  • DMDA1
  • gamma sarcoglycan
  • gamma-Sarcoglycan
  • gamma-SG
  • LGMD2C
  • LGMDR5
  • MAM
  • MGC130048
  • sarcoglycan, gamma (35kD dystrophin-associated glycoprotein)
  • sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
  • SCARMD2
  • SCG3
  • SCG3LGMD2C
  • TYPE

Background

gamma Sarcoglycan encodes gamma-sarcoglycan, one of several sarcolemmal transmembrane glycoproteins that interact with dystrophin. The dystrophin-glycoprotein complex (DGC) spans the sarcolemma and is comprised of dystrophin, syntrophin, alpha- and beta-dystroglycans and sarcoglycans. The DGC provides a structural link between the subsarcolemmal cytoskeleton and the extracellular matrix of muscle cells. Defects in the encoded protein can lead to early onset autosomal recessive muscular dystrophy, in particular limb-girdle muscular dystrophy, type 2C (LGMD2C). [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Bioinformatics

Gene Symbol SGCG