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FPRL1/FPR2 Antibody [Biotin]

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Product Details

Summary
Reactivity Hu, Mu, Rt, BaSpecies Glossary
Applications WB, Flow, ICC/IF, IHC, MS
Clonality
Polyclonal
Host
Rabbit
Conjugate
Biotin

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 405
NLS1878AF405
Alexa Fluor 488
NLS1878AF488
Alexa Fluor 647
NLS1878AF647
Alexa Fluor 700
NLS1878AF700
DyLight 405
NLS1878V
DyLight 488
NLS1878G
DyLight 550
NLS1878R
DyLight 650
NLS1878C
FITC
NLS1878F
HRP
NLS1878H
Unconjugated
NLS1878
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NLS1878
BSA Free
NLS1878
BSA Free
NLS1878SS
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FPRL1/FPR2 Antibody [Biotin] Summary

Immunogen
This FPRL1/FPR2 antibody is made to a synthetic peptide from the human FPRL1 protein (between residues 300-350) [UniProt P25090]
Localization
Cell membrane; Multi-pass membrane protein.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
FPR2
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Electron Microscopy
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Readout System

Reactivity Notes

Rat reactivity reported in scientific literature (PMID: 24086560). Bacteria reactivity reported in scientific literature (PMID: 31234710).

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for FPRL1/FPR2 Antibody [Biotin]

  • ALXR
  • FMLP-R-I
  • FMLP-R-II
  • FMLPX
  • formyl peptide receptor 2
  • Formyl peptide receptor-like 1RFP
  • FPR2
  • FPR2A
  • FPRH1FMLP-related receptor I
  • FPRL1
  • FPRL1LXA4 receptor
  • HM63
  • HM63FPRH2
  • lipoxin A4 receptor (formyl peptide receptor related)
  • Lipoxin A4 receptor
  • LXA4 Receptor
  • LXA4RFMLP-R-I
  • N-formyl peptide receptor 2
  • RFP

Background

Formyl peptide receptor-like receptor 1 (FPRL1), a chemo-attractant receptor also called Lipoxin A4 Receptor (LXA4R), functions as a component of the inflammatory response. The stimulation of FPRL1 results in neutrophil activation and desensitization of chemokine receptors in monocytes (PubMed ID: 11015447). The FPRL1 receptor is up-regulated by interleukin-1 in normal human synovial fibroblasts. The immunodeficiency virus type 1 (HIV-1) envelope protein gp41 can activate the innate host immune cells through FPRL1 and induces directional migration and calcium mobilization in human monocytes and neutrophils. FPRL1 has been reported in phagocytes, monocytes, neutrophils, differentiated myeloid cells from bone marrow, granulocyte HL-60 cells, and synovial fibroblasts. Expressed sequence tags (ESTs) for FPRL1 have been isolated from blood, leukocyte, lung, and placenta libraries. Recently, FPRL1 has been implicated in Alzheimers Disease. Note that Formyl peptide receptor-like receptor 1 (FPRL1) and Formyl peptide receptor 2 (FPR2) are the same, but FPR2 is distinct from FPRL2.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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FPRL1/FPR2
Antibody [Biotin]
NLS1878B
FPRL1/FPR2 Antibody [Biotin]
Species: Hu, Mu, Rt, Ba
Applications: WB, Flow, ICC/IF, IHC, MS

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for FPRL1/FPR2 Antibody (NLS1878B). (Showing 1 - 1 of 1 FAQ).

  1. I am looking for an FPRL1 antibody that is reactive to mouse only. Does Novus have the antibody in question?
    • To answer your question, unfortunately all our FPRL1 antibodies are polyclonal and would detect both mouse and human formyl peptide receptor-like-1 and we do not have any mouse monoclonal antibody for it.

Secondary Antibodies

 

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Bioinformatics

Gene Symbol FPR2