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Ficolin-3 Antibody

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Western Blot: Ficolin-3 Antibody [H00008547-D01P] - Analysis of FCN3 expression in transfected 293T cell line by FCN3 polyclonal antibody.Lane 1: FCN3 transfected lysate(31.70 KDa).Lane 2: Non-transfected lysate.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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Ficolin-3 Antibody Summary

Description
Quality control test: Antibody reactive against mammalian transfected lysate.
Immunogen
FCN3 (AAH20731.1, 1 a.a. - 288 a.a.) full-length human protein. MDLLWILPSLWLLLLGGPACLKTQEHPSCPGPRELEASKVVLLPSCPGAPGSPGEKGAPGPQGPPGPPGKMGPKGEPGPRNCRELLSQGATLSGWYHLCLPEGRALPVFCDMDTEGGGWLVFQRRQDGSVDFFRSWSSYRAGFGNQESEFWLGNENLHQLTLQGNWELRVELEDFNGNRTFAHYATFRLLGEVDHYQLALGKFSEGTAGDSLSLHSGRPFTTYDADHDSSNSNCAVIVHGAWWYASCYRSNLNGRYAVSEAAAHKYGIDWASGRGVGHPYRRVRMMLR
Specificity
Reacts with ficolin (collagen/fibrinogen domain containing) 3 (Hakata antigen).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
FCN3
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • Western Blot
Application Notes
This antibody is reactive against transfected lysate in WB and as a detection antibody in ELISA.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Ficolin-3 Antibody

  • Collagen/fibrinogen domain-containing lectin 3 p35
  • Collagen/fibrinogen domain-containing protein 3
  • FCNHficolin 3
  • ficolin (collagen/fibrinogen domain containing) 3 (Hakata antigen)
  • ficolin (collagen/fibrinogen domain-containing) 3 (Hakata antigen)
  • ficolin-3
  • HAKA1MGC22543
  • Hakata antigen
  • H-ficolin

Background

Ficolins are a group of proteins which consist of a collagen-like domain and a fibrinogen-like domain. In human serum, there are two types of ficolins, both of which have lectin activity. The protein encoded by this gene is a thermolabile beta-2-macroglycoprotein found in all human serum and is a member of the ficolin/opsonin p35 lectin family. The protein, which was initially identified based on its reactivity with sera from patients with systemic lupus erythematosus, has been shown to have a calcium-independent lectin activity. The protein can activate the complement pathway in association with MASPs and sMAP, thereby aiding in host defense through the activation of the lectin pathway. Alternative splicing occurs at this locus and two variants, each encoding a distinct isoform, have been identified. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol FCN3
Entrez
Uniprot