Fc gamma RI/CD64 Antibody (1) [DyLight 650] Summary
Additional Information |
Recombinant Monoclonal Antibody |
Immunogen |
This antibody was obtained from a rabbit immunized with purified, recombinant Mouse Fc gamma RI/CD64 extracellular domain (Accession#: NP_034316.1; Met 1-Pro 297). |
Specificity |
Has cross-reactivity in ELISA with:
Human CD64 / FCGR1A No cross-reactivity in ELISA with:
Mouse CD16-2 /FCGR4 Mouse FCGR2B / CD32 Mouse FCGR3 / CD16 Human CD16a / FCGR3A Human CD16b / FCGR3B Human CD32a / FCGR2A Human CD32b / FCGR2B |
Isotype |
IgG |
Clonality |
Monoclonal |
Host |
Rabbit |
Gene |
FCGR1A |
Purity |
Protein A purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- ELISA
- Immunohistochemistry-Paraffin
|
Application Notes |
Optimal dilution of this antibody should be experimentally determined. |
Packaging, Storage & Formulations
Storage |
Store at 4C in the dark. |
Buffer |
50mM Sodium Borate |
Preservative |
0.05% Sodium Azide |
Purity |
Protein A purified |
Notes
DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.
Alternate Names for Fc gamma RI/CD64 Antibody (1) [DyLight 650]
Background
CD64 is a 72 kD single chain type I glycoprotein also known as Fc gammaRI and FcR I. CD64 is a member of the immunoglobulin superfamily and is expressed on monocytes/macrophages, dendritic cells, and activated granulocytes. The expression can be upregulated by IFN- gamma stimulation. CD64 binds IgG immune complex. It plays a role in antigen capture, phagocytosis of IgG/antigen complexes, and antibody-dependent cellular cytotoxicity (ADCC).
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Secondary Antibodies
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