Home » EMMPRIN/CD147 » EMMPRIN/CD147 Antibodies » EMMPRIN/CD147 Antibody (OX-47) [DyLight 550]
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EMMPRIN/CD147 Antibody (OX-47) [DyLight 550]

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Product Details

Summary
Reactivity RtSpecies Glossary
Applications WB, Flow, ICC/IF, IHC, CyTOF-ready
Clone
OX-47
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 550

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NB100-64848AF350
Alexa Fluor 405
NB100-64848AF405
Alexa Fluor 488
NB100-64848AF488
Alexa Fluor 532
NB100-64848AF532
Alexa Fluor 594
NB100-64848AF594
Alexa Fluor 647
NB100-64848AF647
Alexa Fluor 700
NB100-64848AF700
Alexa Fluor 750
NB100-64848AF750
Allophycocyanin
NB100-64848APC
Biotin
NB100-64848B
DyLight 350
NB100-64848UV
DyLight 405
NB100-64848V
DyLight 488
NB100-64848G
DyLight 594
NB100-64848DL594
DyLight 650
NB100-64848C
DyLight 680
NB100-64848FR
DyLight 755
NB100-64848IR
FITC
NB100-64848F
HRP
NB100-64848H
Janelia Fluor 549
NB100-64848JF549
Janelia Fluor 646
NB100-64848JF646
PE
NB100-64848PE
PerCP
NB100-64848PCP
Unconjugated
NB100-64848
mFluor Violet 450 SE
NB100-64848MFV450
mFluor Violet 500 SE
NB100-64848MFV500
mFluor Violet 610 SE
NB100-64848MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NB100-64848
BSA Free
NB100-64848SS
BSA Free
NB100-64848
Azide and BSA Free
NBP2-80717
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EMMPRIN/CD147 Antibody (OX-47) [DyLight 550] Summary

Immunogen
T blasts from a mixed lymphocyte reaction.
Specificity
NB100-64848 recognizes a membrane glycoprotein of MW 42-48 kD expressed at high levels on activated lymphocytes but lower levels on resting cells. The antigen is also present on some endothelia. The antigen contains two Ig-like domains and an unusual transmembrane domain with a charged residue. It is abundant on activated lymphocytes: it is the homologue of the chicken blood brain barrier antigen HT7.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
BSG
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for EMMPRIN/CD147 Antibody (OX-47) [DyLight 550]

  • 5F7
  • basigin (Ok blood group)
  • Basigin
  • BSG
  • CD147 antigen
  • CD147
  • Collagenase stimulatory factor
  • EMMPRIN
  • EMMPRINTCSF
  • Extracellular matrix metalloproteinase inducer
  • Leukocyte activation antigen M6
  • M6
  • OK blood group antigen
  • OK
  • Tumor cell-derived collagenase stimulatory factor

Background

CD147 plays a pivotal role in spermatogenesis, embryo implantation, neural network formation and tumor progression. It stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). CD147 may target monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to plasma membranes of retinal pigment epithelium and neural retina. CD147 also seems to be a receptor for oligomannosidic glycans. In vitro, it promotes outgrowth of astrocytic processes. CD147 forms homooligomers in a cis-dependent manner on the plasma membrane. It forms a complex with MMP1 at the tumor cell surface. CD147 interacts with SLC16A1 and SLC1A3; probably a BSG dimer is associated with a monocarboxylate transporter dimer. CD147 also interacts with ATP1B2, MAG and L1CAM.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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EMMPRIN/CD147
Antibody (OX-47) [DyL ...
NB100-64848R
EMMPRIN/CD147 Antibody (OX-47) [DyLight 550]
Species: Rt
Applications: WB, Flow, ICC/IF, IHC, CyTOF-ready

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol BSG