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Connexin 43/GJA1 Antibody

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Immunohistochemistry-Paraffin: Connexin 43/GJA1 Antibody [NB110-55546] - Analysis of anti-GJA1 / Connexin 43 antibody with human testis, seminiferous tubules and Leydig cells at concentration 20 ug/ml.
Immunohistochemistry-Paraffin: Connexin 43/GJA1 Antibody [NB110-55546] - Analysis of anti-GJA1 / Connexin 43 antibody with human testis, seminiferous tubules and Leydig cells at concentration 20 ug/ml.

Product Details

Summary
Reactivity Hu, Mu, Rt, Po, Bv, Ca, Gp, Ha, Pm, Pm, Rb, Bt, Ch, Eq, Ma-OpSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.2 mg/ml

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Connexin 43/GJA1 Antibody Summary

Description
Product can be stored undiluted at 4C for up to 1 month.
Immunogen
Synthetic 16 amino acid peptide from C-terminus of human Connexin 43/GJA1.
Epitope
C-terminal domain of human
Marker
Gap Junctions Marker
Specificity
Human Connexin 43/GJA1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Predicted Species
Opossum (100%), Chicken (94%), Bat (94%), Equine (94%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
GJA1
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 10-20 ug/ml
  • Immunohistochemistry-Paraffin 10-20 ug/ml
Application Notes
.
Control
Connexin 43/GJA1 Overexpression Lysate
Publications
Read Publication using NB110-55546.

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Marmoset (100%), Zebrafish (81%).

Packaging, Storage & Formulations

Storage
Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
0.2 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Connexin 43/GJA1 Antibody

  • Connexin 43
  • connexin-43
  • CX43
  • CX43gap junction protein, alpha-like
  • DFNB38
  • Gap junction 43 kDa heart protein
  • gap junction alpha-1 protein
  • gap junction protein, alpha 1, 43kDa (connexin 43)
  • gap junction protein, alpha 1, 43kDa
  • GJA1
  • GJAL
  • HSS
  • ODD
  • ODDD
  • ODOD
  • SDTY3

Background

GJA1 is a member of the connexin gene family and a component of gap junctions. Gap junctions are composed of arrays of intercellular channels and provide a route for the diffusion of materials of low molecular weight from cell to cell. GJA1 is the major protein of gap junctions in the heart, and gap junctions are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. GJA1 is targeted by several protein kinases that regulate myocardial cell cell coupling. A related intronless GJA1 pseudogene, GJA1P, has been mapped to chromosome 5.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Connexin 43/GJA1 Antibody (NB110-55546)(1)


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FAQs for Connexin 43/GJA1 Antibody (NB110-55546) (0)

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Control Lysate(s)

Connexin 43/GJA1 Overexpression Lysate

Secondary Antibodies

 

Isotype Controls

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Blogs on Connexin 43/GJA1.

Check out the latest blog posts on Connexin 43/GJA1.
Connexin: Bridging the Gap of Intercellular Communication
Connexin 43/GJA1 is a member of the connexin gene family and the most abundant protein component found within gap junctions. Gap junctions are the cell-to-cell contacts that provide direct intercellular communication between cells by regulating back a...  Read full blog post.
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Bioinformatics

Gene Symbol GJA1
Entrez