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C1QB Antibody (C1QB/2966)

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Immunohistochemistry-Paraffin: C1QB Antibody (C1QB/2966) [NBP2-79788] - Formalin-fixed, paraffin-embedded human Hepatocellular Carcinoma stained with C1QB Antibody (C1QB/2966).
Immunohistochemistry-Paraffin: C1QB Antibody (C1QB/2966) [NBP2-79788] - Formalin-fixed, paraffin-embedded human Hepatocellular Carcinoma stained with C1QB Antibody (C1QB/2966).
Protein Array: C1QB Antibody (C1QB/2966) [NBP2-79788] - Analysis of Protein Array containing more than 19,000 full-length human proteins using C1QB Antibody (C1QB/2966).Z- and S- Score: The Z-score represents the ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC, MA
Clone
C1QB/2966
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
0.2 mg/ml

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C1QB Antibody (C1QB/2966) Summary

Description
200ug/ml of antibody purified from Bioreactor Concentrate by Protein A or G. Prepared in 10 mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0 mg/ml. (NBP2-79922)

Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80C.
Immunogen
Recombinant fragment (around aa 41-188) of human C1QB protein (exact sequence is proprietary) (Uniprot: P02746)
Localization
Cell Surface, Cytoplasm
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
C1QB
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1-2 ug/ml
  • Immunohistochemistry-Paraffin 1-2 ug/ml
  • Protein Array
Application Notes
Immunohistochemistry (Formalin-fixed): 1-2ug/ml for 30 minutes at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 minutes.
Optimal dilution for a specific application should be determined.

Packaging, Storage & Formulations

Storage
Store at 4C.
Buffer
10 mM PBS with 0.05% BSA
Preservative
0.05% Sodium Azide
Concentration
0.2 mg/ml
Purity
Protein A or G purified

Alternate Names for C1QB Antibody (C1QB/2966)

  • B chain
  • complement C1q subcomponent subunit B
  • complement component 1, q subcomponent, B chain
  • complement subcomponent C1q chain B
  • q subcomponent, beta polypeptide

Background

C1QB encodes a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. This gene encodes the B-chain polypeptide of human complement subcomponent C1q [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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By Jamshed Arslan, Pharm. D., PhD. Cancers in the brain often come from tumors elsewhere in the body. Several adaptive mechanisms influence brain metastasis, such as blood brain barrier leakage that can be induced by ...  Read full blog post.

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Bioinformatics

Gene Symbol C1QB
Uniprot