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Adenylosuccinate Lyase Antibody (OTI2D10) [CoraFluor™ 1]

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Product Details

Summary
Reactivity Hu, Mu, Rt, Ca, Pm, PmSpecies Glossary
Applications WB, Flow, IHC, CyTOF-ready
Clone
OTI2D10
Clonality
Monoclonal
Host
Mouse
Conjugate
CoraFluor 1

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-70101AF350
Alexa Fluor 405
NBP2-70101AF405
Alexa Fluor 488
NBP2-70101AF488
Alexa Fluor 532
NBP2-70101AF532
Alexa Fluor 594
NBP2-70101AF594
Alexa Fluor 647
NBP2-70101AF647
Alexa Fluor 700
NBP2-70101AF700
Alexa Fluor 750
NBP2-70101AF750
Allophycocyanin
NBP2-70101APC
Allophycocyanin/Cy7
NBP2-70101APCCY7
Biotin
NBP2-70101B
DyLight 350
NBP2-70101UV
DyLight 405
NBP2-70101V
DyLight 488
NBP2-70101G
DyLight 550
NBP2-70101R
DyLight 594
NBP2-70101DL594
DyLight 650
NBP2-70101C
DyLight 680
NBP2-70101FR
DyLight 755
NBP2-70101IR
FITC
NBP2-70101F
HRP
NBP2-70101H
Janelia Fluor 525
NBP2-70101JF525
Janelia Fluor 549
NBP2-70101JF549
Janelia Fluor 585
NBP2-70101JF585
Janelia Fluor 635
NBP2-70101JF635
Janelia Fluor 646
NBP2-70101JF646
Janelia Fluor 669
NBP2-70101JF669
PE
NBP2-70101PE
PE/Atto594
NBP2-70101PEATT594
PE/Cy5.5
NBP2-70101PECY55
PE/Cy7
NBP2-70101PECY7
PerCP
NBP2-70101PCP
Unconjugated
NBP2-03107
mFluor Violet 450 SE
NBP2-70101MFV450
mFluor Violet 500 SE
NBP2-70101MFV500
mFluor Violet 610 SE
NBP2-70101MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-03107
Azide and BSA Free
NBP2-70101
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Adenylosuccinate Lyase Antibody (OTI2D10) [CoraFluor™ 1] Summary

Immunogen
Full length human recombinant protein of human ADSL (NP_000017) produced in HEK293T cell.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
ADSL
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
  • Immunohistochemistry
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark. Do not freeze.
Buffer
PBS
Preservative
No Preservative
Purity
Immunogen affinity purified

Notes

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

Alternate Names for Adenylosuccinate Lyase Antibody (OTI2D10) [CoraFluor™ 1]

  • adenylosuccinase
  • adenylosuccinate lyase
  • AMPS
  • ASase
  • ASL
  • EC 4.3.2
  • EC 4.3.2.2

Background

Adenylsuccinate lyase is involved in both de novo synthesis of purines and formation of adenosine monophosphate from inosine monophosphate. It catalyzes two reactions in AMP biosynthesis: the removal of a fumarate from succinylaminoimidazole carboxamide (SAICA) ribotide to give aminoimidazole carboxamide ribotide (AICA) and removal of fumarate from adenylosuccinate to give AMP. Adenylosuccinase deficiency results in succinylpurinemic autism, psychomotor retardation, and , in some cases, growth retardation associated with muscle wasting and epilepsy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol ADSL