Species: Hu, Mu
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, ELISA, Flow, ICC/IF, IHC
Host: Rabbit Monoclonal
Species: Hu, Mu, Rt
Applications: WB, ICC/IF
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Description
In eukaryotes, DNA is wrapped around histone octamers to form the basic unit of chromatin structure. The octamer is composed of Histones H2A, H2B, H3 and H4, and it associates with approximately 200 base pairs of DNA to form the nucleosome. The association of DNA with histones results in dense packing of chromatin, which restricts proteins involved in gene transcription from binding to DNA. Histone H3, the core protein of the nucleosome, becomes phosphorylated at the end of prophase. The two major sites of phosphorylation are the mitosis-specific site Ser 10 and Ser 28, both of which are extensively phosphorylated in DNA-bound forms of Histone H3 and in nucleosomal Histone H3. The nucleosome structure of Histone H3 promotes N-terminal phosphorylation in vitro. Phosphorylation of Histone H3 at Ser 10 is an essenti
Bioinformatics
Entrez |
Rat Mouse Human |
Uniprot |
Human Human |
Product By Gene ID |
8353 |
Alternate Names |
- H3 histone family, member D
- H3.1HIST1H3D
- H3/d
- H3FA
- H3FB
- H3FC
- H3FDHIST1H3F
- H3FF
- H3FH
- H3FI
- H3FJ
- H3FK
- H3FL
- HIST1H3A
- HIST1H3B
- HIST1H3C
- HIST1H3G
- HIST1H3H
- HIST1H3I
- HIST1H3J
- histone 1, H3e
- histone cluster 1, H3e
- histone H3.1
- Histone H3/a
- Histone H3/b
- Histone H3/c
- Histone H3/d
- Histone H3/f
- Histone H3/h
- Histone H3/i
- Histone H3/j
- Histone H3/k
- Histone H3/l
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