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Vitamin A Deficiency: Disease Bioinformatics

Low levels of vitamin A is known as Vitamin A Deficiency and causes preventable blindness and severe visual impairment in infants. It also causes night blindness in pregnant women and raises the risk of mortality in maternal years. A lack of Vitamin A depletes the immune system in infants and it is more likely that they will die from measles, or respiratory infections. Symptoms of Vitamin A deficiency consist of dry eyes, dry skin, inflammation of the eyes, and reduced vision at night. To prevent Vitamin A deficiency, staying healthy and nutrition are key, taking supplements can also help.

Top Research Reagents

We have 3147 products for the study of Vitamin A Deficiency that can be applied to Chromatin Immunoprecipitation (ChIP), Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot from our catalog of antibodies and ELISA kits.

CYP26A1 Antibody (1E1D2)
NBP3-16627
Western Blot: CYP26A1 Antibody (1E1D2) [NBP3-16627] - Western blot analysis of extracts of Rat liver, using CYP26A1 Rabbit mAb (NBP3-16627) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 180s.Immunocytochemistry/Immunofluorescence: CYP26A1 Antibody (1E1D2) [NBP3-16627] - Immunofluorescence analysis of mouse placenta cells using CYP26A1 Rabbit mAb (NBP3-16627) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.

Rabbit Monoclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

C-Reactive Protein/CRP [HRP]
DCRP00B
N/A C-Reactive Protein/CRP [HRP]N/A C-Reactive Protein/CRP [HRP]


Species Human
Applications ELISA

148 Publications
COX5A Antibody
NBP1-32550
Western Blot: COX5A Antibody [NBP1-32550] - Various whole cell extracts (30 ug) were separated by 15% SDS-PAGE, and the membrane was blotted with COX5A antibody [N1C3] diluted at 1:5000. The HRP-conjugated anti-rabbit IgG antibody (NBP2-19301) was used to detect the primary antibody, and the signal was developed with Trident ECL plus-Enhanced.Immunocytochemistry/Immunofluorescence: COX5A Antibody [NBP1-32550] - A431.

Rabbit Polyclonal
Species Human, Mouse, Zebrafish
Applications WB, ICC/IF, IHC

3 Publications
RAR alpha/NR1B1 Antibody (763)
NB200-322
Western Blot: Retinoic Acid Receptor alpha Antibody (763) [NB200-322] - Analysis of hippocampal lysate showing specific immunolabeling of the ~48k RAR-a protein.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

     1 Review

1 Publication
Recombinant Human RAB40B GST (N-Term) Protein
H00010966-P01
12.5% SDS-PAGE Stained with Coomassie Blue.


Species Human
Applications WB, ELISA, PA

RENBP Antibody
NBP1-80851
Western Blot: RENBP Antibody [NBP1-80851] - Analysis in mouse liver tissue and rat liver tissue.Immunohistochemistry-Paraffin: RENBP Antibody [NBP1-80851] - Staining of human cerebral cortex, colon, kidney and lymph node using Anti-RENBP antibody NBP1-80851 (A) shows similar protein distribution across tissues to independent antibody NBP1-80852 (B).

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, IHC, IHC-P

2 Publications
SF4 Antibody
NBP1-88000
Western Blot: SF4 Antibody [NBP1-88000] - Analysis in U2OS cells transfected with control siRNA, target specific siRNA probe #1 and #2. Remaining relative intensity is presented.Immunocytochemistry/Immunofluorescence: SF4 Antibody [NBP1-88000] - Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

Retinol Binding Protein RBP Antibody (OTI2H3)
NBP2-00637
Western Blot: Retinol Binding Protein RBP Antibody (2H3) [NBP2-00637] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY Retinol Binding Protein RBP (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-Retinol Binding Protein RBP.Immunocytochemistry/Immunofluorescence: Retinol Binding Protein RBP Antibody (2H3) [NBP2-00637] Staining of COS7 cells transiently transfected by pCMV6-ENTRY Retinol Binding Protein RBP.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, Flow, ICC/IF

CSRP1 Antibody
AF5739
Western blot shows lysates of ME-180 human cervical epithelial carcinoma cell line, HT-2 mouse T cell line, and Rat-2 rat embryonic fibroblast cell line. PVDF membrane was probed with 0.5 µg/mL Goat Anti-Human/Mouse/Rat CSRP1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF5739) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # <a class=

Goat Polyclonal
Species Human, Mouse, Rat
Applications WB

Albumin Antibody (188835) [Unconjugated] - Serum
MAB1455
Western blot shows lysate of human liver tissue. PVDF membrane was probed with 1 µg/mL of Mouse Anti-Human Serum Albumin Monoclonal Antibody (Catalog # MAB1455) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # <a class=Albumin was detected in immersion fixed BG01V human embryonic stem cells differentiated to hepatocytes using Mouse Anti-Human Serum Albumin Monoclonal Antibody (Catalog # MAB1455) at 10 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Mouse IgG Secondary Antibody (red; Catalog # <a class=

Mouse Monoclonal
Species Human
Applications WB, Simple Western, IHC

     3 Reviews

54 Publications
RBP4/Retinol-Binding Protein 4 [HRP]
DRB400
N/A RBP4/Retinol-Binding Protein 4 [HRP]N/A RBP4/Retinol-Binding Protein 4 [HRP]


Species Human
Applications ELISA

29 Publications
Holo-Transferrin [Unconjugated]
2914-HT


Species Human
Applications BA

47 Publications
LIGHT/TNFSF14 [Unconjugated]
664-LI
<P align=left>Recombinant Human LIGHT/TNFSF14 (Catalog # 664-LI) stimulates cell proliferation in HUVEC human umbilical vein endothelial cells. The ED<SUB>50</SUB> is 1-4 ng/mL.</P><p align=


Species Human
Applications BA

21 Publications
IL-10 [Biotin]
DY417
N/A IL-10 [Biotin]


Species Mouse
Applications ELISA

291 Publications
CD4 Antibody - BSA Free
NBP1-19371
Immunohistochemistry: CD4 Antibody [NBP1-19371] - Increased CD3+ and CD4+ T-cell occurrence in the brainstem of SHR-72 transgenic rat model for tauopathies. (A-D) Immunofluorescence staining showed CD4+ T-cells in SHR-72 transgenic animals. (E- H) Immunofluorescence staining showed more perivascular than brain parenchyma infiltrating CD4+ T-cells in SHR-72 transgenic animals. PLoS One. 2019 May 23;14(5):e0217216. doi: 10.1371/journal.pone.0217216.Immunohistochemistry: CD4 Antibody [NBP1-19371] - DBZ inhibits the accumulation of CD4+ T cells and Th2 differentiation in the AAAs. (B) The representation of immunohistochemical staining for CD4+ in abdominal aorta from four groups (left). Bar graphs show the percentage of CD4+ positive cell areas (right; n=3 per group). Bar: 50 um.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, Simple Western, Flow

     9 Reviews

50 Publications
Transthyretin/Prealbumin Antibody (2E10C5) - BSA Free
NBP2-52575
Western Blot: Transthyretin/Prealbumin Antibody (2E10C5) [NBP2-52575] - Analysis using TTR mAb against human TTR (AA: 1-147) recombinant protein. (Expected MW is 45.8 kDa)Immunocytochemistry/Immunofluorescence: Transthyretin/Prealbumin Antibody (2E10C5) [NBP2-52575] - Analysis of MCF-7 cells using TTR mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.

Mouse Monoclonal
Species Human
Applications WB, ELISA, Flow

     1 Review

1 Publication
Rhodopsin Antibody (4D2)
NBP2-59690
Western Blot: Rhodopsin Antibody (4D2) [NBP2-59690] - Western Blot analysis of Human A549 cells showing detection of ~38.9kDa Rhodopsin protein using Mouse Anti-Rhodopsin Monoclonal Antibody, Clone 4D2 (NBP2-59690). Lane 1: MW ladder. Lane 2: Human A549 Cells 15 ug). Load: 15 ug. Block: 5% Skim Milk Powder in TBST. Primary Antibody: Mouse Anti-Rhodopsin Monoclonal Antibody (NBP2-59690) at 1:1000 for 2.5 hours at RT with shaking . Secondary Antibody: Goat anti-mouse IgG:HRP at 1:1000 for 1 hour at RT with shaking . Color Development: Chemiluminescent for HRP (Moss) for 5 min in RT. Predicted/Observed Size: ~38.9kDa. Other Band(s): Band appears at ~75 kDa indicating detection of the Rhodopsin dimer.Immunohistochemistry: Rhodopsin Antibody (4D2) [NBP2-59690] - Immunohistochemistry analysis using Mouse Anti-Rhodopsin Monoclonal Antibody, Clone 4D2 (NBP2-59690). Tissue: retina. Species: Mouse. Primary Antibody: Mouse Anti-Rhodopsin Monoclonal Antibody (NBP2-59690) at 1:1000. Secondary Antibody: FITC Goat Anti-Mouse (green). Counterstain: DAPI (blue) nuclear stain. Localization: Staining of photoreceptor outer segment (OS). Other layers of the retina: IS inner segment; ONL outer nuclear layer; OPL outer plexiform layer; INL inner nuclear layer; IPL inner plexiform layer; GCL ganglion cell layer..

Mouse Monoclonal
Species Amphibian, Avian, Fish
Applications WB, ELISA, ICC/IF

     1 Review

6 Publications

Related Genes

Vitamin A Deficiency has been researched against:

Related Pathways

Vitamin A Deficiency has been linked to:

Related Diseases

Vitamin A Deficiency has been studied in relation to diseases such as:

Related PTMs

Vitamin A Deficiency has been studied in relation to posttranslational modifications (PTMs) including:

Alternate Names

Vitamin A Deficiency is also known as Deficiencies, Vitamin A, Deficiency Of Vitamin A, Deficiency, Vitamin A, Hypovitaminosis A, Vitamin A Deficiencies.