VAMP-2 Products

Description

Vesicle-associated membrane protein (VAMP), also known as synaptobrevin, is an 18 kDa integral membrane protein localized to the cytoplasmic surface of synaptic vesicle (2). VAMP consists of a proline-rich amino-terminal region, a highly conserved hydrophilic domain, followed by a transmembrane anchor and a carboxylterminal tail (3). Two VAMP homologs, VAMP1 and VAMP2, are differentially expressed in the nervous system (3). VAMP1 expression is localized to neurons involved in modulating overlapping patterns, whereas VAMP2 is found in neurons ssociated with autonomic, sensory and integrative functions. In non-neuronal tissues, VAMP1 is restricted to pancreas and kidney tubular cells, whereas VAMP2 is predominantly expressed in Langerhans islets and glomerular cells (4). Evidences for VAMP

Bioinformatics

Entrez	22318 Mouse 24803 Rat 6844 Human
Uniprot	NP_055047 Human P63027 Human P63045 Rat
Product By Gene ID	6844
Alternate Names	FLJ11460 SYB2vesicle-associated membrane protein 2 synaptobrevin 2 Synaptobrevin-2 synaptobrevin-2 VAMP-2vesicle associated membrane protein 2 vesicle-associated membrane protein 2 (synaptobrevin 2)

Research Areas for VAMP-2

Find related products by research area and learn more about each of the different research areas below.

Membrane Vesicle Markers
Neuronal Cell Markers
Neuroscience
Neurotransmission