Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Hu, Mu
Applications: WB, IHC
Host: Rabbit Monoclonal
Species: Hu
Applications: WB
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
The caspase recruitment domain (CARD) is a protein module that consists of 6 or 7 antiparallel alpha helices. It participates in apoptosis signaling through highly specific protein-protein homophilic interactions. CARDs induce nuclear factor kappa-B (NFKB; MIM 164011) activity through the IKK (e.g., IKBKB; MIM 603258) complex. CARD9 (MIM 607212), CARD10, CARD11 (MIM 607210), and CARD14 (MIM 607211) interact with BCL10 (MIM 603517) and are involved in NFKB signaling complexes. Except for CARD9, these CARD proteins are members of the membrane-associated guanylate kinase (MAGUK) family.
Bioinformatics
Entrez |
Human |
Uniprot |
Human Human Human Human |
Product By Gene ID |
29775 |
Alternate Names |
- CARD-containing MAGUK 3 protein
- CARD-containing MAGUK protein 3
- Carma 3
- CARMA3BIMP1Bcl10 binding protein and activator of NFKB
- caspase recruitment domain family, member 10
- caspase recruitment domain-containing protein 10
- MGC142219
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Research Areas for CARD10
Find related products by research area and learn more about each of the different research areas below.
Apoptosis