Arylsulfatase B/ARSB Products

Description

Arylsulfatase B encoded by this gene belongs to the sulfatase family. The arylsulfatase B homodimer hydrolyzes sulfate groups of N-Acetyl-D-galactosamine, chondriotin sulfate, and dermatan sulfate. The protein is targetted to the lysozyme. Mucopolysaccharidosis type VI is an autosomal recessive lysosomal storage disorder resulting from a deficiency of arylsulfatase B. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq]

Bioinformatics

Entrez	411 Human
Uniprot	NM_000046 Human NP_000037.2 Human NP_942002 Human P15848 Human
Product By Gene ID	411
Alternate Names	arylsulfatase B ASB EC 3.1.6.12 G4S MPS6 N-acetylgalactosamine-4-sulfatase