CD44 Products

Description

CD44 represents a family of type I transmembrane glycoproteins expressed on many cell types such as B cells, monocytes, macrophages, and variable subsets of thymocytes and peripheral T cells. CD44 primarily functions as an adhesion molecule. It has been implicated in various processes, such as hematopoiesis, lymphocyte homing, leukocyte activation, tumor metastasis and development. The KM201 monoclonal antibody reacts with an epitope very close to the hyaluronate binding domain on the CD44 molecule. KM201 can inhibit hyaluronate-dependent cell aggregation, prevent lympho-hemopoiesis in both Dexter and Whitlock-Witte Cultures, prevent the earliest intrathymic precursors from homing to the thymus, and costimulate the activation of freshly purified splenic CD4+ T cells.1-6

Bioinformatics

Entrez	12505 Mouse 25406 Rat 960 Human
Uniprot	AAH04372 Human ENSP00000263398 Human NM_001001391 Human NP_000601 Human NP_001001389 Human P15379 Mouse P16070 Human P26051 Rat
Product By Gene ID	960
Alternate Names	CD44 antigen CD44 molecule (Indian blood group) CD44R CDw44 cell surface glycoprotein CD44 chondroitin sulfate proteoglycan 8 CSPG8 ECMR-III epican Epican Extracellular matrix receptor III GP90 lymphocyte homing/adhesion receptor HCELL hematopoietic cell E- and L-selectin ligand Heparan sulfate proteoglycan Hermes antigen homing function and Indian blood group system HUTCH-I Hyaluronate receptor IN LHR MC56 MDU2CD44 antigen (homing function and Indian blood group system) MDU3CDW44 MIC4MGC10468 Pgp1 PGP-1 PGP-I Phagocytic glycoprotein 1 Phagocytic glycoprotein I

Research Areas for CD44

Find related products by research area and learn more about each of the different research areas below.

Cancer
CD Markers
Cell Biology
Extracellular Matrix
Hematopoietic Stem Cell Markers
Immunology
Mesenchymal Stem Cell Markers
Signal Transduction
Stem Cell Markers

Related CD44 Blog Posts

Check out the latest blog posts on CD44.

CD Antibodies Uncover Markers for Rare Breast Cancer We at Novus Biologicals have added several new products to our CD antibody database. The CD, or Cluster of Differential proteins are a family of type I transmembrane glycoproteins widely expressed in immune cell populations. These include B cells, thy...    Read more.

The Osteopontin Antibody and Hepatic Research Antibody suppliers, such as us at Novus Biologicals, supply a wide range of cell marker products, among them the Osteopontin antibody. Recently, the osteopontin antibody has proven useful in hepatic cancer research.Osteopontin (OPN) is mainly expres...    Read more.

Stemness is responsible for onset and metastasis of colorectal cancer By Jamshed Arslan, Pharm. D., PhD. Colorectal cancer stem cells are a rare subpopulation of colorectal cancer cells that can self-renew and initiate and sustain tumor growth when transplanted into an animal host.1,2 C...    Read more.

Taking Biomarker Discovery From 2D to 3D: Increased Biological Activity of EVs Isolated From 3D Prostate Cancer Cultures Jamshed Arslan, Pharm D, PhD Tissues within the human body are made of a three-dimensional (3D) arrangement of cells working together to perform vital functions. The commonly used 2D monolayer cultures have limited ...    Read more.

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