ATG10 Products

Description

Atg10 is a major contributor to cellular homeostasis is the ability of the cell to strike a balance between the formation and degradation/removal of its cellular components. This process of internal cellular turn-over is called autophagy (self-eating), and is facilitated by a pathway of around 16 interacting proteins in the human. APG10 interacts with LC3A to facilitate the conjugation of ATG12 to ATG5. APG10 is also able to directly interact either with ATG5 or ATG7A. A disruption to the autophagic process is now associated with the progression of several cancers, neurodegenerative disorders and cardiac pathologies.

Bioinformatics

Entrez	83734 Human
Uniprot	EAW95884 Human NM_031482 Human NP_001124500 Human NP_113670.1 Human Q9H0Y0 Human
Product By Gene ID	83734
Alternate Names	APG10 autophagy 10-like (S. cerevisiae) APG10 APG10L APG10-like ATG10 autophagy related 10 homolog (S. cerevisiae) Autophagy-related protein 10 DKFZp586I0418 DKFZP586I0418 EC 6.3.2.- FLJ13954 pp12616 ubiquitin-like-conjugating enzyme ATG10

Research Areas for ATG10

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Autophagy

Related ATG10 Blog Posts

Check out the latest blog posts on ATG10.

From Then ‘till Now: The History of Autophagy and Cancer Research By Christina Towers, PhD. The fundamental process that cells use to degrade damaged cytoplasmic material and recycle nutrients is called autophagy.  This term was first coined by the Belgium biochemist Christian de...    Read more.

Animal Models to Study Autophagy By Christina Towers, PhD What is autophagy?Autophagy is the catabolic process that degrades cytoplasmic material via the lysosome. The process of macroautophagy was originally characterized in yeast, where the...    Read more.

ATG12 - a ubiquitin-like protein essential for autophagosome assembly Atg12 is a ubiquitin-like protein that plays an essential role in cellular homeostasis by regulating the degradation and recycling of cytoplasmic organelles and macromolecules. Atg12 is one of two ubiquitin-like protein systems that is required du...    Read more.

Read more ATG10 related blogs.