TRPM8, or transient receptor potential melastatin 8, is a nonselective cation channel that is activated by cold environments and menthol-like cooling compounds. While TRPM8 is best known for its location in peripheral nerve endings, it has functionality both inside and out of the nervous system. Within the nervous system, TRPM8 is responsible for our response to cold and or menthol like stimuli. Our reaction to cold sensation is involved in a variety of processes and can be a part of reactions such as asthma. Outside of the nervous system, TRPM8 has shown high expression in pro
