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MCT1 antibody

Monocarboxylate Transporter 1 (MCT1) - a novel oncogene

MCT1 is a proton-linked transport carrier that catalyzes the movement of short chain monocarboxylates (branched-chain oxo acids derived from leucine, valine, and isoleucine) across both plasma and inner mitochondrial membranes. In particular, substances such as lactate, pyruvate, butyrate, and ketone bodies are shuttled; these play big roles in cell metabolism particularly in tissues and organs like the kidney, intestine, liver, and brain.