Monocyte Chemoattractant Protein (MCP1) is a potent monocyte attractant, is a member of the CC chemokine subfamily. MCP1 exerts its effects through binding to G-protein-coupled receptors on the surface of leukocytes targeted for activation and migration. The role of MCP1 and its receptor, chemokine receptor-2 (CCR2), in monocyte recruitment during infection or under other inflammatory conditions is well known. Recent studies indicate that MCP-1 may play an important role in pulmonary inflammation.
