Macrophage mannose receptor 1 (MRC1), also known as CD206, is a Pattern Recognition Receptor (PRR). PRRs are expressed by antigen processing and presentation cells, and are activated upon detection of Pathogen-Associated Molecular Patterns (PAMPs). PAMPs are molecular sequences shared by large groups of pathogens, which are essential for microbial survival and/or pathogenicity and include cell wall components such as glycoproteins.
