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A link between Autophagy and Apoptosis: Chat with First Author Brent E. Fitzwalter

Apoptosis poster Novus Biologicals

By Christina Towers, PhD.

Tags: 
Autophagy
autophagosome
Lysosome
Apoptosis
FOXO3A
PUMA

The inflammasome: an inflammation-initiating machine, Novus Biologicals

ASC/TMS1 expression in Hela cells ICC

By Stephanie Melchor

Tags: 
IL-18
IL-1 beta
ASC/TMS1
Microglia
NLRP1
NLRP3
Caspase-1
ALS
epilepsy
Inflammation
inflammasome
Alzheimer’s
Parkinson’s
Innate Immunity
neurodegeneration
Neuroscience
immunology
Pyroptosis

Epigenetic Control of Autophagy

G9a expression in human MCF7 cell line ICC, immunocytochemistry, immunofluorescence, IF

By Christina Towers, PhD.

Tags: 
Autophagy
Epigenetics
autophagosome
mTOR
EZH2
TSC2
carm1
tfeb
AMPK
skp2
LC3B
WIPI1
tp53imp2
BRD4
transcription factor E3
mitf
g9a-ehmt2
Autophagic flux
Methylation
Acetylation
DNA methyltransferase
mTORC
Christina Towers

Bad news for stomach cancer: BAMBI protein inhibits gastric carcinoma via TGF-beta/epithelial-mesenchymal transition signaling

Collagen-I expression in rat colon tissue IHC

By Jamshed Arslan Pharm.D.

Tags: 
Epigenetics
Cancer
Tumor
Hypoxia
TGF-beta
HIF-1 alpha
Bambi
SOX4
VIM
MMP9
Ki67
IPO-38
N-cadherin
Collagen-1
Snai1
Acta2
Twist1
Fibronectin
EMT

Chemotherapy-induced metastasis: An unexpected foe?

Mena plasma membrane, cytosol and focal adhesion expression in human cell line U-2 OS ICC

By Yoskaly Lazo-Fernandez, PhD

Tags: 
TMEM
Breast Cancer
Tie-2
VEGF
ATF3
MENA
macrophages
Metastasis
T Cells
NK cells
immunology
Cancer
Cancer Research

Advancing CAR T Therapies with CRISPR/Cas9

Expression of CD4 and CD8 in peripheral blood mononuclear cells ICC

By Victoria Osinski

Tags: 
CRISPR-Cas9
Lymphocytes
T Cells
Tumor
Cancer
Cancer Research
CAR-T
Immunotherapy
Immuno-oncology
immunology
CRISPR/Cas9

How a cell "reaches" out for help

Expression of alpha-synuclein in rat neuron-glial cultures ICCchloroquine-treated, ICC

By Christina Towers, PhD.

Tags: 
Autophagy
autophagosome
Lysosome
LC3
p62/SQSTM1
neurodegeneration
al2/SQSTM1
Parkinson's
F-actin
Lamp-1pha-synuclein
p6

Combined NOTCH/MAPK inhibition: A promising new anticancer approach

MAPK signaling pathway Novus Biologicals

By Yoskaly Lazo-Fernandez, PhD

Tags: 
NOTCH
MAPK
Colon Cancer
MEK
EMT
NICD
FRA1
Cancer
Metastasis
Tumor

Rescuing motor neuronal loss in amyotrophic lateral sclerosis by inhibiting phosphatidylinositol-4 kinase

Novus C. elegans antibodies

By Jamshed Arslan Pharm.D.

Tags: 
VAPB
PIK
PI4KIIIbeta
ALS
Neuroscience
motor neuron

Measuring Autophagic Flux with LC3 protein levels: The do's and don'ts

Expression of p62/SQSTM1 in HeLa cells mock- or chloroquine-treated, ICC

By Christina Towers, PhD.

Tags: 
Autophagy
autophagosome
Lysosome
LC3
p62/SQSTM1
Chloroquine
Autophagic flux

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