Antibody catalog

Recombinant proteins are those derived from recombinant DNA. Recombinant DNA is an artificial form of DNA, made by combining protein sequences which would not occur in their natural state.

Antibody conjugation involves tagging on a protein, compound or dye, in order to track its interaction with specific antigens. It is a routine procedure in immunoassays. We at Novus Biologicals have a vast number of products in our conjugated antibody catalog, to which we are constantly adding.

A conjugated antibody (also known as a tagged, loaded or labeled antibody) is one that has been attached to a substrate such as an enzyme, toxin or inorganic compound. Modern immunoassay techniques frequently use proteins conjugated with a fluorescent dye. Contemporary antibody sources sometimes supply a wide range of both polyclonal and monoclonal conjugated antibodies.

Bcl-2 antibodies are used as markers for the Bcl-2 gene. Bcl-2 suppresses apoptosis (controlled cell death) by inhibiting caspase activity and controlling cell membrane permeability. It does this by forming mitochondrial pores on the outer membrane of the mitochondria. However, its exact mechanism of action is still not completely understood.

Researchers routinely use GTP binding antibodies for the research of human disease. Thus it is worthwhile to provide a recap of the GTP binding process.

Fanconi anaemia (FA) is an autosomal-recessive disorder, characterized by skeletal abnormalities, progressive bone marrow failure and cellular hypersensitivity to DNA damaging agents such as Mitomycin C. FA also increases the likelihood of cancerous tumors and childhood leukemia.

Various studies have been performed tracking the involvement of p38 mitogen-activated protein kinase (MAPK) and caspase-3 antibodies in cobalt chloride (CoCl2) induced apoptosis in PC12 cells.

Studies have proven the usefulness of CoCl2 treatment to induce apoptosis in PC12 rat tumor cells. Treating these cells with CoCl2 leads to programmed cell death (apoptosis). Such cells provide a simple and useful model for the study of hypoxia-related neuronal disorders, as hypoxia involves a lack of oxygen.