WNK4 Antibody [DyLight 680] Summary
Immunogen |
A synthetic peptide made to a region of the human WNK4 protein between residues 200-300. [UniProt# Q96J92] |
Isotype |
IgG |
Clonality |
Polyclonal |
Host |
Rabbit |
Gene |
WNK4 |
Purity |
Immunogen affinity purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Electron Microscopy
- Immunohistochemistry
- Immunohistochemistry-Frozen
- Immunohistochemistry-Paraffin
- Immunoprecipitation
- Western Blot
|
Application Notes |
Optimal dilution of this antibody should be experimentally determined. |
Reactivity Notes
Use in Rat reported in scientific literature (PMID:34448462).
Packaging, Storage & Formulations
Storage |
Store at 4C in the dark. |
Buffer |
50mM Sodium Borate |
Preservative |
0.05% Sodium Azide |
Purity |
Immunogen affinity purified |
Notes
DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.
Alternate Names for WNK4 Antibody [DyLight 680]
Background
WNK lysine deficient protein kinase 4 (WNK4) is a cytoplasmic serine-threonine kinase expressed in the distal nephron which likely plays an important role in hypertension. The role of WNK4 in kidney physiology is to act as a molecular switch between NaCl reabsorption (volume retention) and K+ secretion (waste release).
WNK4 mutations have been associated with an autosomal dominant disease called pseudohypoaldosteronism type II.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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