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TWEAK R/TNFRSF12 Antibody

 (1 Publication)
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Western Blot: TWEAK R/TNFRSF12 Antibody [NB100-56636] - Analysis of TweakR in A) human liver lysate , B) mouse liver tissue lysate , and C) rat liver lysate using this antibody at 1:500.
Western Blot: TWEAK R/TNFRSF12 Antibody [NB100-56636] - Analysis of TweakR in A) human liver lysate , B) mouse liver tissue lysate , and C) rat liver lysate using this antibody at 1:500.
Western Blot: TWEAK R/TNFRSF12 Antibody [NB100-56636] - Analysis of TweakR in 293 cells. Untransfected (lane 1) or transfectd with human TweakR (lane 2). Photograph courtesy of Dr. Taly Spivakk, The MD Anderson Cancer ...read more

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.5 mg/ml

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TWEAK R/TNFRSF12 Antibody Summary

Immunogen
This antibody was developed against a synthetic peptide containing amino acids 106-118 (CRREKFTTPIEETG) of human TweakR.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TNFRSF12A
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • Western Blot 2-4 ug/ml
Control
Human Liver Whole Tissue Lysate (Adult Whole Normal)
Mouse Liver Whole Tissue Lysate (Adult Whole Normal)
Publications
Read Publication using
NB100-56636 in the following applications:

  • WB
    1 publication

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS containing 0.05% BSA
Preservative
0.05% Sodium Azide
Concentration
0.5 mg/ml
Purity
Protein G purified

Alternate Names for TWEAK R/TNFRSF12 Antibody

  • CD266 antigen
  • CD266
  • FGF-inducible 14
  • Fibroblast growth factor-inducible immediate-early response protein 14
  • Fn14
  • FN14tumor necrosis factor receptor superfamily member 12A
  • TNFRSF12
  • TNFRSF12A
  • tumor necrosis factor receptor superfamily, member 12A
  • TWEAK R
  • TWEAKR
  • tweak-receptor
  • type I transmembrane protein Fn14

Background

TWEAK is a member of the TNF family and was first described as a weak inducer of apoptosis in demonstrate that this relatively small molecule is a fully transformed cell lines (1, 2). Recently, a receptor for TWEAK was isolated by expression cloning from a HUVEC cell cDNA library (3). TweakR is a small protein belonging to TNF receptor super family. TweakR is capable of intiating a proliferative signal by biding to TRAF1, 2, and 3. TweakR mRNA is upregulated during tissue regeneration in aorta and liver. It may also play a role in vascular cell migration and angiogenesis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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TWEAK R/TNFRSF12
Antibody
NB100-56636
TWEAK R/TNFRSF12 Antibody
Species: Hu, Mu, Rt
Applications: WB
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Publications for TWEAK R/TNFRSF12 Antibody (NB100-56636)(1)

We have publications tested in 1 confirmed species: Rat.

We have publications tested in 1 application: WB.


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Product General Protocols

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Video Protocols

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Control Lysate(s)

Human Liver Whole Tissue Lysate (Adult Whole Normal)
Mouse Liver Whole Tissue Lysate (Adult Whole Normal)

Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol TNFRSF12A
Entrez