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Sulfatase Modifying Factor 2/SUMF2 Antibody

Images

 
Immunohistochemistry-Paraffin: Sulfatase Modifying Factor 2/SUMF2 Antibody [NBP1-84145] - Staining of human skeletal muscle shows low expression as expected.
Immunohistochemistry-Paraffin: Sulfatase Modifying Factor 2/SUMF2 Antibody [NBP1-84145] - Staining of human gallbladder shows strong cytoplasmic positivity in glandular cells.
Immunohistochemistry-Paraffin: Sulfatase Modifying Factor 2/SUMF2 Antibody [NBP1-84145] - Staining of human fallopian tube shows high expression.
Orthogonal Strategies: Immunohistochemistry-Paraffin: Sulfatase Modifying Factor 2/SUMF2 Antibody [NBP1-84145] - Staining in human fallopian tube and skeletal muscle tissues using anti-SUMF2 antibody. ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Validated by:
       

Orthogonal Strategies

 

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Sulfatase Modifying Factor 2/SUMF2 Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: ATSMVQLQGGRFLMGTNSPDSRDGEGPVREATVKPFAIDIFPVTNKDFRDFVREKKYRTEAEMFGWSFVFEDFVSDELRNKATQPMKSVLWWLP
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SUMF2
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:20 - 1:50
  • Immunohistochemistry-Paraffin 1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
Sulfatase Modifying Factor 2/SUMF2 Protein (NBP1-84145PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for Sulfatase Modifying Factor 2/SUMF2 Antibody

  • C-alpha-formyglycine-generating enzyme 2
  • C-alpha-formylglycine-generating enzyme 2
  • DKFZp566I1024
  • DKFZp686I1024
  • DKFZp686L17160
  • DKFZp781L1035
  • FGE2
  • MGC99485
  • paralog of the formylglycine-generating enzyme
  • pFGE
  • sulfatase modifying factor 2
  • sulfatase-modifying factor 2
  • SUMF2

Background

The catalytic sites of sulfatases are only active if they contain a unique amino acid, C-alpha-formylglycine (FGly). The FGly residue is posttranslationally generated from a cysteine by enzymes with FGly-generating activity. The gene described in this record is a member of the sulfatase-modifying factor family and encodes a protein with a DUF323 domain that localizes to the lumen of the endoplasmic reticulum. This protein has low levels of FGly-generating activity but can heterodimerize with another family member - a protein with high levels of FGly-generating activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol SUMF2